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    APPARATUS FOR PRIMING MICROFLUIDICS DEVICES WITH FEEDBACK CONTROL
    6.
    发明公开
    APPARATUS FOR PRIMING MICROFLUIDICS DEVICES WITH FEEDBACK CONTROL 有权
    GERÄTZUR GRUNDIERUNG VON MIKROFLUIDISCHEN VORRICHTUNGEN MIT REGELUNG

    公开(公告)号：EP1819808A4

    公开(公告)日：2007-12-12

    申请号：EP05852690

    申请日：2005-12-01

    Applicant: BIO RAD LABORATORIES ,  CALIPER LIFE SCIENCES INC

    Inventor： BORONKAY ALLEN ,  KENNEDY COLIN ,  LATHAM MATTHEW

    IPC: C12M3/00

    CPC classification number: B01L3/0293 ,  B01L3/5027 ,  B01L9/527 ,  B01L2200/146 ,  B01L2400/0487 ,  G01N27/44743 ,  G01N27/44756 ,  Y10T436/11 ,  Y10T436/25 ,  Y10T436/2575

    Abstract: A priming unit (31) for a microfluidics device (11) containing a pressurization unit (35) and pressure (46) and temperature detectors as part of a feedback loyg (55) that controls the pressure applied by the pressurization unit (35) an the time during which the pressure is applied. This control feature is particularly useful in controlling the exposure time of the microchannels (15) to dyes in the priming liquids since certain dyes tend to adhere to the walls of the channels and produce non-uniform results.

    Abstract translation: 一种用于微流体装置（11）的灌注单元（31），其包含加压单元（35）和压力（46）以及作为控制由加压单元（35）施加的压力的反馈单元（55）的一部分的温度检测器， 施加压力的时间。 这种控制特征对于控制微通道（15）暴露于起动液体中的染料的暴露时间是特别有用的，因为某些染料倾向于粘附在通道的壁上并产生不均匀的结果。

    ELECTROPHORESIS CASSETTE WITH SEALING AND CLOSURE FEATURES
    7.
    发明专利
    ELECTROPHORESIS CASSETTE WITH SEALING AND CLOSURE FEATURES 未知

    公开(公告)号：CA2619866A1

    公开(公告)日：2007-03-22

    申请号：CA2619866

    申请日：2006-08-31

    Applicant: BIO RAD LABORATORIES

    Inventor： LATHAM MATTHEW

    IPC: C25B9/00

    Abstract: Slab gel electrophoresis cassettes constructed from two flat rectangular plates, with features that allow the plates to be joined parallel to and facing each other with a gap between them that is sealed at the sides and open at the top and bottom for access to upper and lower electrodes, respectively, are improved by two independent features. The first is the integration of an elastomeric gasket to the surface of one of the two plates to ensure a liquid-tight seal, while the second is the inclusion of edge engaging members that are mounted to one plate and engage an opposing edge of the other plate. The engaging members are manually engaged and released at will. In preferred constructions, the gasket is a strip that extends along the two sides and bottom of one of the plates, and each engaging member is pivotally and resiliently mounted to achieve a snap-type engagement.

    ELECTROBLOTTING CASSETTE WITH MANUALLY RELEASABLE ELECTRODES OF ADJUSTABLE SPACING
    8.
    发明专利
    ELECTROBLOTTING CASSETTE WITH MANUALLY RELEASABLE ELECTRODES OF ADJUSTABLE SPACING 未知

    公开(公告)号：SG173721A1

    公开(公告)日：2011-09-29

    申请号：SG2011059045

    申请日：2010-02-22

    Applicant: BIO RAD LABORATORIES

    Inventor： LATHAM MATTHEW

    IPC: C25B9/19

    Abstract: An electroblotting cassette is formed in three separable parts—an upper plate, a lower plate, and a base that receives both plates, with electrodes mounted on both the upper and lower plates. The cassette accommodates transfer stacks of different thicknesses by its inclusion of a set of raised areas, known as “lands,” on the floor of the base and a set of inverse lands on the underside of the lower electrode plate, the two sets being spatially arranged to either abut each other or be offset from each other, depending on the orientation of the lower plate, thereby allowing the user a choice between two heights of the lower plate within the base and hence two thicknesses of transfer stacks. Other arrangements include those with more than one set of lands on one or both parts to allow for three or more thickness selections, or depressions in place of lands. Finger-operated latches secure the upper plate to the base.

    ELECTROPHORESIS CASSETTE WITH SEALING AND CLOSURE FEATURES
    9.
    发明申请
    ELECTROPHORESIS CASSETTE WITH SEALING AND CLOSURE FEATURES 审中-公开
    具有密封和闭合功能的电泳盒

    公开(公告)号：WO2007032951A3

    公开(公告)日：2007-11-08

    申请号：PCT/US2006034473

    申请日：2006-08-31

    Applicant: BIO RAD LABORATORIES ,  LATHAM MATTHEW

    Inventor： LATHAM MATTHEW

    IPC: C25B9/00

    CPC classification number: G01N27/44704

    Abstract: Slab gel electrophoresis cassettes constructed from two flat rectangular plates, with features that allow the plates to be joined parallel to and facing each other with a gap between them that is sealed at the sides and open at the top and bottom for access to upper and lower electrodes, respectively, are improved by two independent features. The first is the integration of an elastomeric gasket to the surface of one of the two plates to ensure a liquid-tight seal, while the second is the inclusion of edge engaging members that are mounted to one plate and engage an opposing edge of the other plate. The engaging members are manually engaged and released at will. In preferred constructions, the gasket is a strip that extends along the two sides and bottom of one of the plates, and each engaging member is pivotally and resiliently mounted to achieve a snap-type engagement.

    Abstract translation: 由两块扁平矩形板构成的平板凝胶电泳盒，具有允许板彼此平行且面向彼此连接的特征，其间具有间隙，所述间隙在侧面密封并且在顶部和底部开口用于进入上部和下部 电极分别通过两个独立的特征得到改进。 第一种是将弹性垫圈集成到两块板之一的表面上以确保液密密封，而第二种是包括安装到一块板上并接合另一块板的相对边缘的边缘接合构件 盘子。 接合件可以随意手动接合和释放。 在优选的构造中，垫圈是沿一个板的两侧和底部延伸的条，并且每个接合构件枢转且弹性地安装以实现卡扣式接合。

    DIMENSIONAL STABILIZATION OF SLAB GEL CASSETTES TO PREVENT DISTORTION CAUSED BY SWELLING GELS
    10.
    发明专利
    DIMENSIONAL STABILIZATION OF SLAB GEL CASSETTES TO PREVENT DISTORTION CAUSED BY SWELLING GELS 未知

    公开(公告)号：SG192792A1

    公开(公告)日：2013-09-30

    申请号：SG2013062146

    申请日：2012-02-24

    Applicant: BIO RAD LABORATORIES

    Inventor： PANATTONI CORY ,  LATHAM MATTHEW ,  KIMMEL KARA ,  WALKER JOHN

    Abstract: Slab gel cassettes for use in electrophoretic analyses of biologically-derived mixtures are equipped with features that prevent the plastic walls of the cassettes from bowing outward when gels retained within the cassettes swell, as gels typically do during casting, storage, or both. In certain embodiments, these features are incorporated into, or mate with, the comb-shaped inserts that form the sample wells as the gels are being cast. In other embodiments, these features are complementary features incorporated into both the comb and the cassette.

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