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公开(公告)号：AU2018308077A1
公开(公告)日：2020-02-13
申请号：AU2018308077
申请日：2018-07-24
Applicant: CHEMIMAGE CORP
Inventor： NELSON MATTHEW , VOIGT THOMAS , CHATSKO MAXXWELL , TREADO PATRICK , SCHULER REBECCA , STEWART SHONA , MCGLONE JAMES , KLUEVA OKSANA , GOMER NATHANIEL
IPC: G01J3/02 , G01J3/32 , G01N21/25 , G02F1/1347
Abstract: Conformal vision with enhanced image processing of the outputted image is incorporated into novel applications. The conformal vision provides enhanced contrast by the combined inclusion of tunable filters and processing of the images that are generated by the detector. Furthermore, novel uses and applications of the conformal vision enable users to make determinations related to their health and wellness utilizing information provided by the conformal vision.
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公开(公告)号：CA2890437C
公开(公告)日：2021-02-02
申请号：CA2890437
申请日：2013-11-06
Applicant: CHEMIMAGE CORP , TREADO PATRICK , STEWART SHONA , KIRSCHNER HEATHER , PRIORE RYAN , WILSON ALAN
Inventor： TREADO PATRICK , STEWART SHONA , KIRSCHNER HEATHER , PRIORE RYAN , WILSON ALAN
Abstract: A system and method for analyzing biological samples, such as dried human blood serum, to determine a disease state such as colorectal cancer (CRC). Using dried samples may hold potential for enhancing localized concentration and/or segmentation of sample components. The method may comprise illuminating at least one location of a biological sample to generate a plurality of interacted photons, collecting the interacted photons and generating at least one Raman data set representative of the biological sample. A system may comprise an illumination source to illuminate at least one location of a biological sample and generate at least one plurality of interacted photons, at least one mirror for directing the interacted photons to a detector. The detector may be configured to generate at least one Raman data set representative of the biological sample. The system and method may utilize a FAST device for multipoint analysis or may be configured to analyze a sample using a line scanning configuration.
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公开(公告)号：AU2013341327A1
公开(公告)日：2015-07-02
申请号：AU2013341327
申请日：2013-11-06
Applicant: CHEMIMAGE CORP , KIRSCHNER HEATHER , PRIORE RYAN , STEWART SHONA , TREADO PATRICK , WILSON ALAN
Inventor： TREADO PATRICK , STEWART SHONA , KIRSCHNER HEATHER , PRIORE RYAN , WILSON ALAN
IPC: G01N33/574 , G01N33/48 , G01N33/53
Abstract: A system and method for analyzing biological samples, such as dried human blood serum, to determine a disease state such as colorectal cancer (CRC). Using dried samples may hold potential for enhancing localized concentration and/or segmentation of sample components. The method may comprise illuminating at least one location of a biological sample to generate a plurality of interacted photons, collecting the interacted photons and generating at least one Raman data set representative of the biological sample. A system may comprise an illumination source to illuminate at least one location of a biological sample and generate at least one plurality of interacted photons, at least one mirror for directing the interacted photons to a detector. The detector may be configured to generate at least one Raman data set representative of the biological sample. The system and method may utilize a FAST device for multipoint analysis or may be configured to analyze a sample using a line scanning configuration.
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公开(公告)号：AU2019232890A1
公开(公告)日：2019-10-10
申请号：AU2019232890
申请日：2019-09-19
Applicant: CHEMIMAGE CORP
Inventor： TREADO PATRICK , STEWART SHONA , KIRSCHNER HEATHER , PRIORE RYAN , WILSON ALAN
IPC: G01N33/574 , G01N33/48 , G01N33/53
Abstract: A system and method for analyzing biological samples, such as dried human blood serum, to determine a disease state such as colorectal cancer (CRC). Using dried samples may hold potential for enhancing localized concentration and/or segmentation of sample components. The method may comprise illuminating at least one location of a biological sample to generate a plurality of interacted photons, collecting the interacted photons and generating at least one Raman data set representative of the biological sample. A system may comprise an illumination source to illuminate at least one location of a biological sample and generate at least one plurality of interacted photons, at least one mirror for directing the interacted photons to a detector. The detector may be configured to generate at least one Raman data set representative of the biological sample. The system and method may utilize a FAST device for multipoint analysis or may be configured to analyze a sample using a line scanning configuration.
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公开(公告)号：CA2890437A1
公开(公告)日：2014-05-15
申请号：CA2890437
申请日：2013-11-06
Applicant: CHEMIMAGE CORP , TREADO PATRICK , STEWART SHONA , KIRSCHNER HEATHER , PRIORE RYAN , WILSON ALAN
Inventor： TREADO PATRICK , STEWART SHONA , KIRSCHNER HEATHER , PRIORE RYAN , WILSON ALAN
IPC: G01N33/574 , G01N33/48 , G01N33/53
Abstract: A system and method for analyzing biological samples, such as dried human blood serum, to determine a disease state such as colorectal cancer (CRC). Using dried samples may hold potential for enhancing localized concentration and/or segmentation of sample components. The method may comprise illuminating at least one location of a biological sample to generate a plurality of interacted photons, collecting the interacted photons and generating at least one Raman data set representative of the biological sample. A system may comprise an illumination source to illuminate at least one location of a biological sample and generate at least one plurality of interacted photons, at least one mirror for directing the interacted photons to a detector. The detector may be configured to generate at least one Raman data set representative of the biological sample. The system and method may utilize a FAST device for multipoint analysis or may be configured to analyze a sample using a line scanning configuration.
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Patent Agency Ranking6.发明申请SYSTEM AND METHOD FOR CYTOLOGICAL ANALYSIS BY RAMAN SPECTROSCOPIC IMAGING 审中-公开通过拉曼光谱成像进行细胞分析的系统和方法
公开(公告)号：WO2007056560A2
公开(公告)日：2007-05-18
申请号：PCT/US2006043755
申请日：2006-11-09
Applicant: CHEMIMAGE CORP , MAIER JOHN S , COHEN JEFFREY , MCCLELLAND LINDY , STEWART SHONA
Inventor： MAIER JOHN S , COHEN JEFFREY , MCCLELLAND LINDY , STEWART SHONA
CPC classification number: G01N33/5005 , G01N15/1459 , G01N21/65 , G01N33/574 , G01N33/57407 , G01N2021/656
Abstract: A method and system of differentially manipulating cells where the cells, suspended in a fluid, are irradiated with substantially monochromatic light. A Raman data set is obtained from the irradiated cells and where the data set is characteristic of a disease status. The data set is assessed to identify diseased cells. A Raman chemical image of the irradiated cells is also obtained. Based on the assessment and the Raman chemical image, the fluid in which the cells are suspended is differentially manipulated. The diseased cells are directed to a first location and other non-diseased cells are directed to a second location as part of the differential manipulation. The diseased cells may be treated with a physical stress, a chemical stress, and a iological stress and then returned to a patient from whom the diseased cells were obtained prior to the irradiation.
Abstract translation: 一种差异操纵细胞的方法和系统，其中悬浮在流体中的细胞用基本上单色的光照射。 从照射的细胞获得拉曼数据集，其中数据集是疾病状态的特征。 评估数据集以鉴定患病细胞。 还获得了照射的细胞的拉曼化学图像。 基于评估和拉曼化学图像，细胞悬浮的流体被差异地操纵。 病变细胞被引导到第一位置，并且其他非病变细胞被引导到第二位置作为差异操纵的一部分。 患病细胞可以用物理应力，化学应力和生理压力进行治疗，然后返回到在照射之前从其获得患病细胞的患者。
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公开(公告)号：WO2006007063A2
公开(公告)日：2006-01-19
申请号：PCT/US2005016140
申请日：2005-05-06
Applicant: CHEMIMAGE CORP , MAIER JOHN S , NEISS JASON H , STEWART SHONA
Inventor： MAIER JOHN S , NEISS JASON H , STEWART SHONA
IPC: G01J3/51
CPC classification number: G01J3/28 , G01J3/0227 , G01J3/027 , G01J3/0286 , G01J3/44
Abstract: In one embodiment the disclosure relates to a method and a system for determining the corrected wavelength of a photon scattered by a sample. The method includes the steps of determining a wavelength of a photon scattered from a sample exposed to illuminating photons and passed through a tunable filter and correcting the determined wavelength of the photon as a function of the temperature of the tunable filter and as a function of the bandpass set point of the tunable filter. The step of correcting the determined wavelength can further include determining an offset and adding the offset to the determined wavelength of the photon.
Abstract translation: 在一个实施例中，本公开涉及用于确定由样本散射的光子的校正波长的方法和系统。 该方法包括以下步骤：确定从暴露于照射光子并通过可调谐滤光器的样品散射的光子的波长，并根据可调谐滤光器的温度校正所确定的光子的波长，并且作为 可调谐滤波器的带通设置点。 校正所确定的波长的步骤可以进一步包括确定偏移并将该偏移添加到所确定的光子的波长。
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公开(公告)号：AU2019232890B2
公开(公告)日：2021-12-23
申请号：AU2019232890
申请日：2019-09-19
Applicant: CHEMIMAGE CORP
Inventor： TREADO PATRICK , STEWART SHONA , KIRSCHNER HEATHER , PRIORE RYAN , WILSON ALAN
IPC: G01N33/574 , G01N33/48 , G01N33/53
Abstract: A system and method for analyzing biological samples, such as dried human blood serum, to determine a disease state such as colorectal cancer (CRC). Using dried samples may hold potential for enhancing localized concentration and/or segmentation of sample components. The method may comprise illuminating at least one location of a biological sample to generate a plurality of interacted photons, collecting the interacted photons and generating at least one Raman data set representative of the biological sample. A system may comprise an illumination source to illuminate at least one location of a biological sample and generate at least one plurality of interacted photons, at least one mirror for directing the interacted photons to a detector. The detector may be configured to generate at least one Raman data set representative of the biological sample. The system and method may utilize a FAST device for multipoint analysis or may be configured to analyze a sample using a line scanning configuration.
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公开(公告)号：CA3070117A1
公开(公告)日：2019-01-31
申请号：CA3070117
申请日：2018-07-24
Applicant: CHEMIMAGE CORP
Inventor： NELSON MATTHEW , VOIGT THOMAS , CHATSKO MAXXWELL , TREADO PATRICK , SCHULER REBECCA , STEWART SHONA , MCGLONE JAMES , KLUEVA OKSANA , GOMER NATHANIEL
IPC: G01J3/02 , G01J3/32 , G01N21/25 , G02F1/1347
Abstract: Conformal vision with enhanced image processing of the outputted image is incorporated into novel applications. The conformal vision provides enhanced contrast by the combined inclusion of tunable filters and processing of the images that are generated by the detector. Furthermore, novel uses and applications of the conformal vision enable users to make determinations related to their health and wellness utilizing information provided by the conformal vision.
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公开(公告)号：CA2572164A1
公开(公告)日：2006-01-19
申请号：CA2572164
申请日：2005-05-06
Applicant: CHEMIMAGE CORP
Inventor： STEWART SHONA , NEISS JASON H , MAIER JOHN S
Abstract: In one embodiment the disclosure relates to a method and a system for determining the corrected wavelength of a photon scattered by a sample. The method includes the steps of determining a wavelength of a photon scattered from a sample exposed to illuminating photons and passed through a tunable filter and correcting the determined wavelength of the photon as a function of the temperature of the tunable filter and as a function of the bandpass set point of the tunable filter. The step of correcting the determined wavelength can further include determining an offset and adding the offset to the determined wavelength of the photon.
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