公开(公告)号：CA2596077A1

公开(公告)日：2006-08-10

申请号：CA2596077

申请日：2006-01-30

Applicant: CHEMIMAGE CORP

Inventor： WANG XINGHUA ,  VOIGHT THOMAS ,  TREADO PATRICK J ,  WANG CHENHUI ,  TUSCHEL DAVID

IPC: G01J3/00 ,  G01J3/28 ,  G01J3/40 ,  G01J3/42 ,  G01J3/44 ,  G01N21/25

公开(公告)号：WO2006083715A3

公开(公告)日：2007-05-10

申请号：PCT/US2006002975

申请日：2006-01-30

Applicant: CHEMIMAGE CORP ,  VOIGHT THOMAS ,  ZHANG JINGYUN ,  TREADO PATRICK J ,  TUSCHEL DAVID

Inventor： VOIGHT THOMAS ,  ZHANG JINGYUN ,  TREADO PATRICK J ,  TUSCHEL DAVID

IPC: G01J3/44

CPC classification number: G01J3/44 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0224 ,  G01N21/65

Abstract: The disclosure relates to identifying one or more regions (100) of interest within a broader field of view (104) of a dynamic sample using one or more optical components (110 & 120) and illuminating photons. Once the region of interest (100) is identified within a section of the broader field of view (104), chemical information in the form of Raman spectrum is obtained from the region of interes (100) by focusing the illuminating photons of the optical components (110 & 120) on the region of interest (100).

Abstract translation: 本公开涉及使用一个或多个光学部件（110和120）和照射光子来识别动态样品的更宽视场（104）内的感兴趣的一个或多个区域（100）。 一旦在较宽视场（104）的一部分内识别出感兴趣区域（100），则通过聚焦光学部件的照明光子，从内部区域（100）获得呈拉曼光谱形式的化学信息 （100）上的（110和120）。

公开(公告)号：WO2006083716A3

公开(公告)日：2007-04-19

申请号：PCT/US2006002976

申请日：2006-01-30

Applicant: CHEMIMAGE CORP ,  WANG XINGHUA ,  VOIGHT THOMAS ,  TUSCHEL DAVID ,  WANG CHENHUI ,  TREADO PATRICK J

Inventor： WANG XINGHUA ,  VOIGHT THOMAS ,  TUSCHEL DAVID ,  WANG CHENHUI ,  TREADO PATRICK J

IPC: G01J3/00 ,  G01J3/28 ,  G01J3/40 ,  G01J3/42 ,  G01J3/44 ,  G01N21/25

CPC classification number: G01N21/65 ,  G01J3/02 ,  G01J3/0291 ,  G01J3/36 ,  G01J3/44 ,  G01N21/359 ,  G01N21/59 ,  G01N21/6458 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/656

Abstract: The disclosure generally relates to a multimode imaging apparatus for simultaneously obtaining multiple wavelength-discriminative spectral images of a sample (100). In one embodiment, the apparatus includes an image selector (108) having a rotator assembly, the rotator assembly housing a first plurality of optical components, the image selector adapted to receive a illuminating photons having a first wavelength and direct the illuminating photons to the sample, the image selector (108) adapted to receive illuminating photons interacted with the sample and selectively direct said interacted photons to one of a plurality of detection sources; a microscope turret (102) housing a second plurality of components, the microscope turret (102) adapted to receive illuminating photons having a second wavelength and direct the photons to the sample; the microscopic turret (102) adapted to receive illuminating photons interacted with the sample and selectively direct said interacted photons to one of a plurality of detection sources; wherein substantially all of the interacted photons are selectively directed one of a plurality of detection sources to form multiple wavelength discriminative spectral images of the sample simultaneously.

Abstract translation: 本公开内容通常涉及用于同时获得样本（100）的多个波长鉴别光谱图像的多模式成像装置。 在一个实施例中，该装置包括具有旋转器组件的图像选择器（108），旋转体组件容纳第一多个光学部件，图像选择器适于接收具有第一波长的照明光子并将照射光子引导至样品 ，所述图像选择器（108）适于接收与所述样本相互作用的照明光子并选择性地将所述相互作用的光子引导到多个检测源中的一个; 显微镜转台（102），其容纳第二多个部件，所述显微镜转台（102）适于接收具有第二波长的照射光子并将所述光子引导到所述样品; 适于接收与样品相互作用的照明光子并且将所述相互作用的光子选择性地引导到多个检测源中的一个的微观炮塔（102）; 其中基本上所有相互作用的光子被选择性地指向多个检测源中的一个，以同时形成样品的多个波长鉴别光谱图像。