公开(公告)号：BR8804512A

公开(公告)日：1989-04-04

申请号：BR8804512

申请日：1988-09-02

Applicant: CIBA GEIGY AG

Inventor： FLURY PETER ,  ADLER ALEX

IPC: C07C279/28 ,  C08G59/40 ,  C08L63/00 ,  C08K5/31

Abstract: Curable epoxy resin compositions containing cyanoguanidines of formula I (I) wherein, for example, R1 and R2 are phenyl, as latent hardeners, have good properties and are especially suitable for use as laminating resins.

公开(公告)号：HU194180B

公开(公告)日：1988-01-28

申请号：HU419386

申请日：1985-06-19

Applicant: CIBA GEIGY AG

Inventor： ADLER ALEX ,  STANEK JAROSLAV ,  BELLUS DANIEL

IPC: A61K31/435 ,  A61P35/00 ,  A61P43/00 ,  C07D211/88 ,  C07D221/22 ,  C07D311/00 ,  C12N9/99

Abstract: 1-Phenyl-3-azabicyclo[3.1.1]-heptane-2,4-diones of the formula (I) in which R1 represents hydrogen or a saturated or unsaturated, aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, aromatic or aromatic-aliphatic hydrocarbon radical having up to and including 18, preferably up to and including 12, carbon atoms, R2 represents hydrogen, lower alkyl, sulpho or acyl, R3 represents hydrogen or lower alkyl and R4 represents hydrogen, lower alkyl, phenyl or phenyl substituted by -N(R2)(R3), and salts of these compounds, have valuable pharmacological properties, are effective as aromatase inhibitors and can therefore be used for the treatment of hormone-dependent diseases, especially mammary carcinoma.