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    MOLECULAR CHEMICAL IMAGING ENDOSCOPIC IMAGING SYSTEMS
    1.
    发明申请
    MOLECULAR CHEMICAL IMAGING ENDOSCOPIC IMAGING SYSTEMS 有权

    公开(公告)号：US20210068639A1

    公开(公告)日：2021-03-11

    申请号：US17027340

    申请日：2020-09-21

    Applicant: ChemImage Corporation

    Inventor： Patrick TREADO ,  Matthew NELSON ,  Shona STEWART

    IPC: A61B1/04 ,  A61B1/06 ,  A61B1/307 ,  A61B1/07 ,  A61B1/00

    Abstract: The instant disclosure provides for medical imaging systems that may be used in conjunction with an intraoperative medical device, such as an endoscope. Generally, the disclosed medical imaging systems include an illumination source configured to generate illuminating photons for illuminating a biological sample. An optical signal modulator is configured to separate one or more of the illuminating photons and photons that have interacted with the biological sample into a first optical signal having first multi-passband wavelengths and a second optical signal having second multi-passband wavelengths. At least one detector is configured to detect one or more of the first optical signal and the second optical signal and generate at least one image data set. A processor is configured to analyze the at least one image data set. In some embodiments, the processor is configured to differentiate between structures of the biological sample, such as between an ureter and surrounding tissue.

    RAMAN-BASED IMMUNOASSAY SYSTEMS AND METHODS
    5.
    发明申请
    RAMAN-BASED IMMUNOASSAY SYSTEMS AND METHODS 审中-公开

    公开(公告)号：US20180348136A1

    公开(公告)日：2018-12-06

    申请号：US15776649

    申请日：2016-11-16

    Applicant: ChemImage Corporation

    Inventor： Patrick TREADO ,  Shona STEWART ,  Aaron SMITH ,  Heather GOMER

    IPC: G01N21/65 ,  G01N21/17 ,  G01J3/44 ,  G01N33/53 ,  G16H50/20

    CPC classification number: G01N21/65 ,  G01J3/44 ,  G01N2201/0833

    Abstract: This disclosure is directed to systems and methods for fusing Raman data with biomarker data to identify a disease and/or the progression of the disease. The system disclosed herein may include an illumination source for generating interacted photons from a biological sample and a detector for detecting the interacted photons to generate a Raman data set. A processor is included to fuse the Raman data set with a biomarker data set to identify a disease and/or a disease progression. The instant disclosure further includes a method comprising illuminating a biological sample to generate interacted photons, and detecting the interacted photons to generate a Raman data set. A biomarker data set is obtained from the biological sample, and the Raman data set is fused with the biomarker data set to generate an index score. The index score correlates with one or more of a disease and a disease progression.

    MOLECULAR CHEMICAL IMAGING ENDOSCOPIC IMAGING SYSTEMS
    6.
    发明申请
    MOLECULAR CHEMICAL IMAGING ENDOSCOPIC IMAGING SYSTEMS 审中-公开

    公开(公告)号：US20180263475A1

    公开(公告)日：2018-09-20

    申请号：US15932435

    申请日：2015-12-09

    Applicant: ChemImage Corporation

    Inventor： Patrick TREADO ,  Matthew NELSON

    IPC: A61B1/04 ,  A61B1/06 ,  A61B1/00 ,  A61B1/307 ,  A61B1/07

    CPC classification number: A61B1/043 ,  A61B1/00009 ,  A61B1/00096 ,  A61B1/00186 ,  A61B1/042 ,  A61B1/0607 ,  A61B1/063 ,  A61B1/0646 ,  A61B1/0653 ,  A61B1/0684 ,  A61B1/07 ,  A61B1/307

    Abstract: The instant disclosure provides for medical imaging systems that may be used in conjunction with an intraoperative medical device, such as an endoscope. Generally, the disclosed medical imaging systems include an illumination source configured to generate illuminating photons for illuminating a biological sample. An optical signal modulator is configured to separate one or more of the illuminating photons and photons that have interacted with the biological sample into a first optical signal having first multi-passband wavelengths and a second optical signal having second multi-passband wavelengths. At least one detector is configured to detect one or more of the first optical signal and the second optical signal and generate at least one image data set. A processor is configured to analyze the at least one image data set. In some embodiments, the processor is configured to differentiate between structures of the biological sample, such as between an ureter and surrounding tissue.

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