公开(公告)号：US20230346983A1

公开(公告)日：2023-11-02

申请号：US17796536

申请日：2021-02-01

Applicant: CytoVeris Inc.

Inventor： Alan Kersey ,  Rishikesh Pandey ,  Patrick Curry

IPC: A61K49/00 ,  A61B5/00 ,  A61K41/00

CPC classification number: A61K49/001 ,  A61B5/0075 ,  A61B5/0091 ,  A61K41/0052

Abstract: A method and system for determining the presence of a mass of cancerous cells in vivo within a tissue body is provided. The method includes: a) performing an examination of the tissue body using a diagnostic method operable to determine the presence of a suspect tissue mass, and determining a location of the same; b) administering a solution containing “RR-CTEs”, the RR-CTEs configured to target and bind with cancerous cells; c) interrogating the tissue body with a beam of light, wherein the RR-CTEs are configured to produce Raman scattered light upon impingement; d) collecting the Raman scattered light; e) processing the collected Raman scattered light to determine a presence or an absence of the a Raman signature; and f) comparing the determined location of the suspect tissue mass with the determined location of the mass of cancerous cells to determine the presence of the mass of cancerous cells.

公开(公告)号：US20240011969A1

公开(公告)日：2024-01-11

申请号：US18271023

申请日：2022-01-05

Applicant: CytoVeris Inc.

Inventor： Rishikesh Pandey ,  David Fournier ,  Patrick Curry ,  Alan Kersey

IPC: G01N33/483 ,  G01N21/64

CPC classification number: G01N33/4833 ,  G01N21/6486 ,  A61B10/00

Abstract: A system and method for analyzing bladder tissue sample is provided that includes an excitation light source, a photodetector, an optical filter, and a system controller. The excitation light source produces excitation lights centered on a distinct wavelengths. At least one of the wavelengths produces autofluorescence emissions from one or more biomolecules, and at least one of the wavelengths produces diffuse reflectance signals. The photodetector detects at least one of the autofluorescence emissions or diffuse reflectance signals and produces signals representative thereof. The optical filter filters at least one of autofluorescence emissions or the diffuse reflectance signals. The system controller communicates with the system components and a memory storing instructions. The instructions cause the system controller to control the excitation light unit, receive and process the photodetector signals, produce a signal image, and analyze the tissue sample to determine the presence of detrusor muscle tissue.