公开(公告)号：WO2020051215A1

公开(公告)日：2020-03-12

申请号：PCT/US2019/049540

申请日：2019-09-04

Applicant: EMD MILLIPORE CORPORATION

Inventor： CATALDO, William ,  AQUINO, Dennis ,  LANDRY, Nathan ,  NGAN, Clifton ,  BARTLETT, Andrew ,  GOMEZ, Maribel ,  STRAEFFER, Gregory ,  LAWSON, Thomas

IPC: B01D61/14 ,  B01D61/24 ,  B01D63/08 ,  B01D63/10 ,  B01D63/14

Abstract: Devices for removing extractables downstream from a filter, including a tangential flow filter, the filter housed within a housing; and an adsorber housed within the frame and downstream of the filter, the adsorber containing media for removing extractables, wherein extractables are removed from a permeate side of the filter without contacting a product of interest, are disclosed.

公开(公告)号：WO2013086498A1

公开(公告)日：2013-06-13

申请号：PCT/US2012/068755

申请日：2012-12-10

Applicant: EMD MILLIPORE CORPORATION

Inventor： NGAN, Clifton ,  MAIDEN, Yu Zou ,  BARTLETT, Andrew

IPC: B01D63/08 ,  B01D69/00 ,  B01D39/08 ,  C07K1/34 ,  C12M1/12

CPC classification number: B01D35/28 ,  B01D39/083 ,  B01D63/08 ,  B01D2313/10 ,  B01D2313/143 ,  C07K1/34

Abstract: A device for the tangential filtration of liquids at high viscosities is taught. For a given channel length and width (relatively fixed by the cassette design), one can decrease the channel pressure drop by increasing the channel height or reducing the channel hydraulic resistance. One can increase the channel height by using a larger diameter fiber in the screen, by increasing the thickness of the molded border or nm on the overmolded screen or by using a thicker nonwoven as a spacer in a non-overmolded screen. Since the screen is embossed into the surface of the membrane: the effective channel height Is also affected by the hardness of the membrane -as well as the fibers In the screen.

Abstract translation: 教导了用于在高粘度下切向过滤液体的装置。 对于给定的通道长度和宽度（通过盒式设计相对固定），可以通过增加通道高度或降低通道液压阻力来减小通道压降。 可以通过在屏幕中使用更大直径的纤维来增加通道高度，通过增加成型边框的厚度或包覆成型的筛网上的nm，或者通过在非包覆模制的筛网中使用较厚的非织造物作为间隔物来增加通道高度。 由于屏幕被压印到膜的表面：有效通道高度也受到膜的硬度以及屏幕中的纤维的影响。

公开(公告)号：EP2788106A1

公开(公告)日：2014-10-15

申请号：EP12856081.0

申请日：2012-12-10

Applicant: EMD Millipore Corporation

Inventor： NGAN, Clifton ,  ZOU, Yu ,  BARTLETT, Andrew ,  HILLIER, Brian

IPC: B01D63/08 ,  B01D69/00 ,  B01D39/08 ,  C07K1/34 ,  C12M1/12

CPC classification number: B01D35/28 ,  B01D39/083 ,  B01D63/08 ,  B01D2313/10 ,  B01D2313/143 ,  C07K1/34

Abstract: A device for the tangential filtration of liquids at high viscosities is taught. For a given channel length and width (relatively fixed by the cassette design), one can decrease the channel pressure drop by increasing the channel height or reducing the channel hydraulic resistance. One can increase the channel height by using a larger diameter fiber in the screen, by increasing the thickness of the molded border or nm on the overmolded screen or by using a thicker nonwoven as a spacer in a non-overmolded screen. Since the screen is embossed into the surface of the membrane: the effective channel height Is also affected by the hardness of the membrane -as well as the fibers In the screen.