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公开(公告)号：WO2022086652A1
公开(公告)日：2022-04-28
申请号：PCT/US2021/051083
申请日：2021-09-20
Applicant: EMD MILLIPORE CORPORATION
Inventor： LI, Ying , DUPONT, Alison , WOOD, Amy , FOURNIER, Allyson , GUPTA, Akshat , GAMI, Hiral
IPC: C12M1/00
Abstract: A multi-stage TFF apparatus, comprising a bioreactor capable of holding cell culture media; a first stage TFF device in fluid communication with the bioreactor; a storage tank in fluid communication with the first stage TFF device; a first recirculating loop in fluid communication with the first stage TFF device and the bioreactor; a second stage TFF device, in fluid communication with and downstream from the storage tank; and a second recirculating loop in fluid communication with the second stage TFF device and the storage tank.
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公开(公告)号：WO2020198527A1
公开(公告)日：2020-10-01
申请号：PCT/US2020/025059
申请日：2020-03-26
Applicant: EMD MILLIPORE CORPORATION
Inventor： GUPTA, Akshat , AMARA, John , PIZZELLI, Kara M. , RYAN, Shannon
Abstract: Depth filters with optimized head space are provided, as well as methods of optimizing the head space in depth filters, and methods of filtration with depth filters having optimized head space, including clarification of flocculated feed streams where pretreatment may include any of lowering cell culture pH, addition of polymers (uncharged or charged), or addition of salts to precipitate out solubilized impurities resulting in high insoluble biomass.
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3.发明申请REDUCTION OF LEACHABLE BETA-GLUCAN LEVELS FROM CELLULOSE-CONTAINING FILTER MATERIALS 审中-公开从含纤维素的过滤材料中减少可浸出的β-葡聚糖水平
公开(公告)号：WO2018080999A1
公开(公告)日：2018-05-03
申请号：PCT/US2017/057878
申请日：2017-10-23
Applicant: EMD MILLIPORE CORPORATION
Inventor： GUPTA, Akshat , KINZLMATER, Dana , PIZZELLI, Kara , GOODRICH, Elizabeth
IPC: B01D39/18
Abstract: Treatment methods for reduction of (1→3)-β-D-glucan leachables from cellulose- containing filter materials are described.
Abstract translation: 描述了从含纤维素过滤材料中还原（1→3）-β-D-葡聚糖可沥滤物的处理方法。
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Patent Agency Ranking
公开(公告)号：WO2019094249A1
公开(公告)日：2019-05-16
申请号：PCT/US2018/058660
申请日：2018-11-01
Applicant: EMD MILLIPORE CORPORATION
Inventor： GOODRICH, Elizabeth M. , GUPTA, Akshat , LUTZ, Herbert
Abstract: Processes and systems for filtering a liquid sample are provided. Batches of a liquid sample can be routed to two or more cycling tanks (e.g., first and second cycling tanks). Upon filling a first cycling tank, a first batch of the liquid sample can be routed to a filtration assembly by a continuous diafiltration process that includes routing produced retentate back to the first cycling tank or to a collection vessel. Upon filling a second cycling tank, a second batch of the liquid sample is routed to the filtration assembly by a continuous diafiltration process that includes routing produced retentate back to the second cycling tank or to the collection vessel. The filling and continuous diafiltration of batches of the liquid sample continues to alternate between the two or more cycling tanks until a total product volume is processed.
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公开(公告)号：WO2018080999A8
公开(公告)日：2018-05-03
申请号：PCT/US2017/057878
申请日：2017-10-23
Applicant: EMD MILLIPORE CORPORATION
Inventor： GUPTA, Akshat , KINZLMAIER, Dana , PIZZELLI, Kara , GOODRICH, Elizabeth
IPC: B01D39/18
Abstract: Treatment methods for reduction of (1→3)-β-D-glucan leachables from cellulose- containing filter materials are described.
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公开(公告)号：EP3710141A1
公开(公告)日：2020-09-23
申请号：EP18804820.1
申请日：2018-11-01
Applicant: EMD Millipore Corporation
Inventor： GOODRICH, Elizabeth M. , GUPTA, Akshat , LUTZ, Herbert
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公开(公告)号：EP3532186A1
公开(公告)日：2019-09-04
申请号：EP17801799.2
申请日：2017-10-23
Applicant: EMD Millipore Corporation
Inventor： GUPTA, Akshat , KINZLMAIER, Dana , PIZZELLI, Kara , GOODRICH, Elizabeth
IPC: B01D39/18
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公开(公告)号：EP3946677A1
公开(公告)日：2022-02-09
申请号：EP20720982.6
申请日：2020-03-26
Applicant: EMD Millipore Corporation
Inventor： GUPTA, Akshat , AMARA, John Paul , PIZZELLI, Kara M. , RYAN, Shannon
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