公开(公告)号：WO2020092688A1

公开(公告)日：2020-05-07

申请号：PCT/US2019/059027

申请日：2019-10-31

Applicant: EMD MILLIPORE CORPORATION

Inventor： KAS, Onur, Y. ,  NGUYEN, Thang ,  SATAV, Nitin ,  CUDDY, Martin

IPC: D01D5/00 ,  D04H1/728

Abstract: Provided herein are electrospinning apparatuses and methods for efficient production of nanofiber structures.

公开(公告)号：WO2013013241A3

公开(公告)日：2013-01-24

申请号：PCT/US2012/047865

申请日：2012-07-23

Applicant: EMD MILLIPORE CORPORATION ,  KAS, Onur, Y. ,  KOZLOV, Mikhail ,  TKACIK, Gabriel ,  NHIEM, David ,  GODDARD, Philip ,  LEON, Sherry, Ashby

Inventor： KAS, Onur, Y. ,  KOZLOV, Mikhail ,  TKACIK, Gabriel ,  NHIEM, David ,  GODDARD, Philip ,  LEON, Sherry, Ashby

IPC: B01D69/12 ,  B01D35/00 ,  B01D39/16 ,  B01D39/08 ,  B01D69/02

Abstract: A nanofiber liquid filtration medium featuring an electrospun polymeric nanofiber layer produced on a smooth non-woven substrate.

公开(公告)号：WO2014093345A1

公开(公告)日：2014-06-19

申请号：PCT/US2013/074132

申请日：2013-12-10

Applicant: EMD MILLIPORE CORPORATION

Inventor： KOZLOV, Mikhail ,  TKACIK, Gabriel ,  KAS, Onur, Y. ,  POTTY, Ajish ,  PATEL, Jigneshkumar

IPC: B01D39/14 ,  B01D39/08 ,  B01D69/06

CPC classification number: B01D71/56 ,  A61L2/022 ,  B01D39/1623 ,  B01D61/145 ,  B01D67/0004 ,  B01D69/06 ,  B01D2239/025 ,  B01D2239/0631 ,  B01D2239/0654 ,  B01D2239/1233 ,  B01D2323/39

Abstract: A porous electrospun polymeric nanofiber liquid filtration medium, such as an electrospun mats, used for the removal of viral particles (e.g., parvovirus) and other particles in the 18 nm to 30 nm size range from fluid streams, having a mean flow bubble point measured with perfluorohexane above 100 psi. The electrospun medium includes nanofibers having an average fiber diameter of about 6 nm to about 13 nm, and the nanofiber liquid filtration medium has a mean pore size ranging from about 0,01 um to about 0,03 um, a porosity ranging from about 80% to about 95%, a thickness ranging from about 1 um to about 100 um, and a liquid permeability greater than about 10 LMH/psi. The high porosity of the electrospun mats enable much higher water fluxes, thus reducing the time required to complete virus filtration steps on a fluid stream.

Abstract translation: 用于从流体流中除去病毒颗粒（例如细小病毒）和其他颗粒的多孔电纺聚合物纳米纤维液体过滤介质，例如电纺丝垫，其具有测量的平均流动泡点 全氟己烷高于100psi。 电纺介质包括具有约6nm至约13nm的平均纤维直径的纳米纤维，并且纳米纤维液体过滤介质的平均孔径为约0.01-1.03μm，孔隙率为约80 ％至约95％，厚度范围为约1μm至约100μm，液体渗透性大于约10LHH / psi。 电纺毡的高孔隙度使得能够获得更高的水通量，从而减少在流体流上完成病毒过滤步骤所需的时间。

公开(公告)号：EP2734290A2

公开(公告)日：2014-05-28

申请号：EP12814718.8

申请日：2012-07-23

Applicant: EMD Millipore Corporation

Inventor： KAS, Onur, Y. ,  KOZLOV, Mikhail ,  TKACIK, Gabriel ,  NHIEM, David ,  GODDARD, Philip ,  LEON, Sherry, Ashby

IPC: B01D69/12 ,  B01D35/00 ,  B01D39/16 ,  B01D39/08 ,  B01D69/02

CPC classification number: B01D69/02 ,  B01D67/0004 ,  B01D2239/025 ,  B01D2239/0618 ,  B01D2239/0631 ,  B01D2239/0654 ,  B01D2323/39 ,  C02F1/444 ,  C02F2303/04

Abstract: A nanofiber liquid filtration medium featuring an electrospun polymeric nanofiber layer produced on a smooth non-woven substrate.

Abstract translation: 一种纳米纤维液体过滤介质，其特征在于在光滑的无纺基材上生产的电纺聚合物纳米纤维层。

公开(公告)号：EP2928577A1

公开(公告)日：2015-10-14

申请号：EP13863417.5

申请日：2013-12-10

Applicant: EMD Millipore Corporation

Inventor： KOZLOV, Mikhail ,  TKACIK, Gabriel ,  KAS, Onur, Y. ,  POTTY, Ajish ,  PATEL, Jigneshkumar

IPC: B01D39/14 ,  B01D39/08 ,  B01D69/06

CPC classification number: B01D71/56 ,  A61L2/022 ,  B01D39/1623 ,  B01D61/145 ,  B01D67/0004 ,  B01D69/06 ,  B01D2239/025 ,  B01D2239/0631 ,  B01D2239/0654 ,  B01D2239/1233 ,  B01D2323/39

Abstract: A porous electrospun polymeric nanofiber liquid filtration medium, such as an electrospun mats, used for the removal of viral particles (e.g., parvovirus) and other particles in the 18 nm to 30 nm size range from fluid streams, having a mean flow bubble point measured with perfluorohexane above 100 psi. The electrospun medium includes nanofibers having an average fiber diameter of about 6 nm to about 13 nm, and the nanofiber liquid filtration medium has a mean pore size ranging from about 0,01 um to about 0,03 um, a porosity ranging from about 80% to about 95%, a thickness ranging from about 1 um to about 100 um, and a liquid permeability greater than about 10 LMH/psi. The high porosity of the electrospun mats enable much higher water fluxes, thus reducing the time required to complete virus filtration steps on a fluid stream.

公开(公告)号：EP3877574A1

公开(公告)日：2021-09-15

申请号：EP19806360.4

申请日：2019-10-31

Applicant: EMD Millipore Corporation

Inventor： KAS, Onur, Y. ,  NGUYEN, Thang ,  SATAV, Nitin ,  CUDDY, Martin

IPC: D01D5/00 ,  D04H1/728

公开(公告)号：EP2603611B1

公开(公告)日：2019-12-18

申请号：EP11816795.6

申请日：2011-07-29

Applicant: EMD Millipore Corporation

Inventor： KAS, Onur, Y. ,  KOZLOV, Mikhail ,  TKACIK, Gabriel ,  MOYA, Wilson ,  GODDARD, Philip ,  LEON, Sherry Ashby ,  HAO, Jibin

IPC: C12Q1/70 ,  C12Q1/24 ,  C12M1/12 ,  C12R1/92 ,  B01D67/00

公开(公告)号：EP2603611A2

公开(公告)日：2013-06-19

申请号：EP11816795.6

申请日：2011-07-29

Applicant: EMD Millipore Corporation

Inventor： KAS, Onur, Y. ,  KOZLOV, Mikhail ,  TKACIK, Gabriel ,  MOYA, Wilson ,  GODDARD, Philip ,  LEON, Sherry ,  HAO, Jibin

IPC: C12Q1/70 ,  C12Q1/24 ,  C12M1/12 ,  C12R1/92

Abstract: A method for removing retroviruses from liquid samples and a nanofiber containing liquid filtration medium that simultaneously exhibits high liquid permeability and high microorganism retention is disclosed. Retroviruses are removed from a liquid by passing the liquid through a porous nanofiber containing filtration medium having a retrovirus LRV greater than about 6, and the nanofiber(s) has a diameter from about 10 nm to about 100 nm. The filtration medium can be in the form of a fibrous electrospun polymeric nanofiber liquid filtration medium mat.

Abstract translation: 公开了一种从液体样品中除去逆转录病毒的方法和含有液体过滤介质的纳米纤维，其同时具有高液体渗透性和高微生物保留性。 通过使液体通过含有大于约6的逆转录病毒LRV的过滤介质的多孔纳米纤维从液体中除去逆转录病毒，并且纳米纤维的直径为约10nm至约100nm。 过滤介质可以是纤维电纺聚合物纳米纤维液体过滤介质垫的形式。