公开(公告)号：CA3112016A1

公开(公告)日：2020-03-19

申请号：CA3112016

申请日：2019-09-09

Applicant: FLUIDIGM CANADA INC ,  GOVERNING COUNCIL UNIV TORONTO

Inventor： CLOSSON TAUNIA ,  BARANOV VLADIMIR ,  WINNIK MITCHELL A

IPC: G01N15/10 ,  G01N33/50

Abstract: This disclosure relates to reagents and their use for elemental imaging mass spectrometry of biological samples.

公开(公告)号：CA3098578A1

公开(公告)日：2019-10-31

申请号：CA3098578

申请日：2019-04-26

Applicant: FLUIDIGM CANADA INC

Inventor： ZABINYAKOV NIKITA ,  LOBODA ALEXANDER V ,  ORNATSKY OLGA ,  BARANOV VLADIMIR ,  MAVROPOULOS ANASTASIA ,  MAJONIS DANIEL ,  ALLO BEDILU ,  CLOSSON TAUNIA

IPC: C12M1/00 ,  C12M1/34 ,  G01N35/00 ,  G01N35/10 ,  H01J49/00 ,  H01J49/02

Abstract: Embodiments of the present invention relate to reagents and their use for elemental imaging mass spectrometry of biological samples. The embodiments comprising methods for quantifying one or more analytes within a sample, comprising the steps of: (a) providing the sample, wherein the one or more analytes are immobilized to a sample carrier, wherein the sample has been labelled with one or more mass tags comprising one or more labelling atoms, (b) performing mass cytometry on the sample to determine the level of the one or more labelling atoms, wherein the level of the one or more labelling atoms corresponds to the copy number of the one or more analytes.