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    IMAGE PROCESSING METHOD AND SYSTEM FOR MICROFLUIDIC DEVICES
    1.
    发明申请
    IMAGE PROCESSING METHOD AND SYSTEM FOR MICROFLUIDIC DEVICES 审中-公开
    图像处理方法和微流体装置系统

    公开(公告)号：WO2005011947A2

    公开(公告)日：2005-02-10

    申请号：PCT/US2004/024591

    申请日：2004-07-28

    Applicant: FLUIDIGM CORPORATION ,  TAYLOR, Colin Jon ,  SUN, Gang ,  DUBE, Simant

    Inventor： TAYLOR, Colin Jon ,  SUN, Gang ,  DUBE, Simant

    IPC: B29C

    CPC classification number: G06K9/36 ,  B01L3/5027 ,  G06K9/00 ,  G06K9/00127 ,  G06K9/00134 ,  G06K9/6232 ,  G06T7/0008 ,  G06T7/0012 ,  G06T7/254 ,  G06T7/33 ,  G06T2207/30004

    Abstract: A method for processing an image of a microfluidic device. The method includes receiving a first image of a microfluidic device. The first image corresponds to a first state. Additionally, the method includes receiving a second image of the microfluidic device. The second image corresponds to a second state. Moreover, the method includes transforming the first image and the second image into a third coordinate space. Also, the method includes obtaining a third image based on at least information associated with the transformed first image and the transformed second image, and processing the third image to obtain information associated with the first state and the second state.

    Abstract translation: 一种用于处理微流体装置的图像的方法。 该方法包括接收微流体装置的第一图像。 第一图像对应于第一状态。 另外，该方法包括接收微流体装置的第二图像。 第二图像对应于第二状态。 此外，该方法包括将第一图像和第二图像变换为第三坐标空间。 此外，该方法包括至少基于与变换的第一图像和变换的第二图像相关联的信息获得第三图像，并且处理第三图像以获得与第一状态和第二状态相关联的信息。

    METHOD AND APPARATUS FOR BIOLOGICAL SAMPLE ANALYSIS
    3.
    发明申请
    METHOD AND APPARATUS FOR BIOLOGICAL SAMPLE ANALYSIS 审中-公开
    生物样品分析方法与装置

    公开(公告)号：WO2008067552A2

    公开(公告)日：2008-06-05

    申请号：PCT/US2007/086146

    申请日：2007-11-30

    Applicant: FLUIDIGM CORPORATION ,  SUN, Gang ,  RAMAKRISHNAN, Ramesh ,  JONES, Robert C.

    Inventor： SUN, Gang ,  RAMAKRISHNAN, Ramesh ,  JONES, Robert C.

    IPC: G06T11/20

    CPC classification number: C12Q1/686 ,  C12Q2565/629 ,  C12Q2565/501 ,  C12Q2545/114

    Abstract: A method of adjusting amplification curves in a PCR experiment includes receiving a plurality of amplification curves for a sample and computing a first parameter for each of the plurality of amplification curves. The method also includes computing a second parameter for each of the plurality of amplification curves and computing a third parameter using at least a portion of the first or second parameters. The method further includes computing an offset for each of the plurality of amplification curves. The offset is a function of the first parameter and the third parameter. Moreover, the method includes adjusting at least one of the plurality of amplification curves by subtracting the offset.

    Abstract translation: 在PCR实验中调整扩增曲线的方法包括接收样品的多个放大曲线并计算多个放大曲线中的每一个的第一参数。 该方法还包括为多个放大曲线中的每一个计算第二参数，并使用第一或第二参数的至少一部分来计算第三参数。 该方法还包括计算多个放大曲线中的每一个的偏移量。 偏移量是第一个参数和第三个参数的函数。 此外，该方法包括通过减去偏移来调整多个放大曲线中的至少一个。

    METHOD AND SYSTEM FOR MICROFLUIDIC DEVICE AND IMAGING THEREOF
    6.
    发明公开
    METHOD AND SYSTEM FOR MICROFLUIDIC DEVICE AND IMAGING THEREOF 审中-公开
    维也纳联合国系统联合国难民事务高级专员办事处

    公开(公告)号：EP1636017A2

    公开(公告)日：2006-03-22

    申请号：EP04753014.2

    申请日：2004-05-20

    Applicant: Fluidigm Corporation

    Inventor： QUAN, Emerson ,  TAYLOR, Colin, Jon ,  LEE, Michael ,  CEASAR, Christopher ,  HARRIS, Greg ,  SUN, Gang

    IPC: B29D11/00

    CPC classification number: G01N33/00 ,  B01L3/5025 ,  B01L3/502707 ,  B01L2200/025 ,  B01L2200/12 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0887 ,  B01L2400/0481 ,  B01L2400/0655 ,  Y10T436/11

    Abstract: A biological substrate, e.g., microfluidic chip. The substrate includes a rigid substrate material, which has a surface region capable of acting as a handle substrate. The substrate also has a deformable fluid layer coupled to the surface region. One or more well regions are formed in a first portion of the deformable fluid layer and are capable of holding a fluid therein. The one or more channel regions are formed in a second portion of the deformable fluid layer and are coupled to one or more of the well regions. An active region is formed in the deformable fluid layer. At least three fiducial markings are formed within the non-active region and disposed in a spatial manner associated with at least one of the well regions. A control layer is coupled to the fluid layer.

    Abstract translation: 生物底物，例如微流体芯片。 衬底包括刚性衬底材料，其具有能够用作处理衬底的表面区域。 衬底还具有耦合到表面区域的可变形流体层。 一个或多个阱区形成在可变形流体层的第一部分中并且能够在其中保持流体。 一个或多个通道区域形成在可变形流体层的第二部分中并且耦合到一个或多个阱区域。 在可变形流体层中形成有源区。 在非有源区域内形成至少三个基准标记，并以与至少一个阱区域相关联的空间方式设置。 控制层耦合到流体层。

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