公开(公告)号：KR820000741B1

公开(公告)日：1982-05-03

申请号：KR810004879

申请日：1981-12-12

Applicant: FUJISAWA PHARMACEUTICAL CO

Inventor： NAKAI Y ,  KAMIYA D ,  SAKANE K ,  TANAKA K

IPC: C07D501/36

公开(公告)号：DK431480A

公开(公告)日：1981-04-13

申请号：DK431480

申请日：1980-10-10

Applicant: FUJISAWA PHARMACEUTICAL CO

Inventor： TERAJI T ,  SAKANE K ,  GOTO J

IPC: C07D20060101 ,  C07D

公开(公告)号：DK502078A

公开(公告)日：1979-05-15

申请号：DK502078

申请日：1978-11-10

Applicant: FUJISAWA PHARMACEUTICAL CO

Inventor： KAMIYA T ,  TERAJI T ,  NAKAI Y ,  SAKANE K ,  GOTO J

IPC: C07D213/55 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D213/73 ,  C07D213/75 ,  C07D213/79 ,  C07D213/80 ,  C07D239/42 ,  C07D239/46 ,  C07D501/20 ,  C07D501/22 ,  C07D501/34 ,  C07D501/36 ,  C07D501/57 ,  C07D501/59 ,  C07D519/06 ,  C07F7/10 ,  C07D

Abstract: A novel compound, useful as an intermediate in the production of compounds of high antimicrobial activity, of the formula: wherein Ra1 is hydrogen, amino or a protected amino group, Rb1 and Rc1 are each hydrogen, halogen, lower alkoxy or arylthio, R14 is carboxy or a protected carboxy group, X is lower alkylene or a group of the formula: in which R6 is hydrogen or an organic residue which may have suitable substituent(s), and Z is N or CH, or a salt thereof.

公开(公告)号：ZA7701060B

公开(公告)日：1978-01-25

申请号：ZA7701060

申请日：1977-02-22

Applicant: FUJISAWA PHARMACEUTICAL CO

Inventor： SAKANE K ,  KAMIYA T ,  TANAKA K ,  NAKAI Y

IPC: C07D277/20 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07C20060101 ,  C07D277/34 ,  C07D277/40 ,  C07D501/20 ,  C07D501/22 ,  C07D501/34 ,  C07D501/36 ,  C07D501/46 ,  C07C

CPC classification number: Y02P20/55

公开(公告)号：SE437832B

公开(公告)日：1985-03-18

申请号：SE7702547

申请日：1977-03-07

Applicant: FUJISAWA PHARMACEUTICAL CO

Inventor： KAMIYA T ,  TANAKA K ,  NAKAI Y ,  SAKANE K

IPC: A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D277/20 ,  C07D277/32 ,  C07D277/34 ,  C07D277/38 ,  C07D277/40 ,  C07D277/44 ,  C07D277/46 ,  C07D277/48 ,  C07D277/52 ,  C07D501/20 ,  C07D501/22 ,  C07D501/34 ,  C07D501/36

Abstract: Antibiotic cephalosporin compounds, method of making and pharmaceutical composition thereof represented by the general formula wherein R1 is amino, lower alkylamino, a protected amino, a protected lower alkylamino, hydroxy or lower alkoxy, R2 is hydrogen, acyloxy, pyridium or a heterocyclicthio group which may have suitable substituent(s), R3 is carboxy or its derivative, A is carbonyl, hydroxy(lower)alkylene or a protected hydroxy(lower)alkylene and R4 is hydrogen or halogen, or R2 and R3 are linked together to represent a group of the formula -COO-, this divisional application being directed to intermediate compounds of the formula:

公开(公告)号：SE8302027L

公开(公告)日：1983-04-12

申请号：SE8302027

申请日：1983-04-12

Applicant: FUJISAWA PHARMACEUTICAL CO

Inventor： KAMIYA T ,  TANAKA K ,  NAKAI Y ,  SAKANE K

IPC: A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D277/20 ,  C07D277/32 ,  C07D277/34 ,  C07D277/38 ,  C07D277/40 ,  C07D277/44 ,  C07D277/46 ,  C07D277/48 ,  C07D277/52 ,  C07D501/20 ,  C07D501/22 ,  C07D501/34 ,  C07D501/36 ,  C07D277/42

Abstract: Antibiotic cephalosporin compounds, method of making and pharmaceutical composition thereof represented by the general formula wherein R1 is amino, lower alkylamino, a protected amino, a protected lower alkylamino, hydroxy or lower alkoxy, R2 is hydrogen, acyloxy, pyridium or a heterocyclicthio group which may have suitable substituent(s), R3 is carboxy or its derivative, A is carbonyl, hydroxy(lower)alkylene or a protected hydroxy(lower)alkylene and R4 is hydrogen or halogen, or R2 and R3 are linked together to represent a group of the formula -COO-, this divisional application being directed to intermediate compounds of the formula:

公开(公告)号：DK249681A

公开(公告)日：1981-12-19

申请号：DK249681

申请日：1981-06-04

Applicant: FUJISAWA PHARMACEUTICAL CO

Inventor： TERAJI T ,  SAKANE K ,  GOTO J

IPC: C07C17/26 ,  C07D257/04 ,  C07D285/08 ,  C07D295/21 ,  C07D501/24 ,  C07D501/46 ,  C07D

公开(公告)号：DK101477A

公开(公告)日：1977-09-10

申请号：DK101477

申请日：1977-03-08

Applicant: FUJISAWA PHARMACEUTICAL CO

Inventor： KAMIYA T ,  TANAKA K ,  NAKAI Y ,  SAKANE K

IPC: A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D277/20 ,  C07D277/32 ,  C07D277/34 ,  C07D277/38 ,  C07D277/40 ,  C07D277/44 ,  C07D277/46 ,  C07D277/48 ,  C07D277/52 ,  C07D501/20 ,  C07D501/22 ,  C07D501/34 ,  C07D501/36 ,  C07D

Abstract: Antibiotic cephalosporin compounds, method of making and pharmaceutical composition thereof represented by the general formula wherein R1 is amino, lower alkylamino, a protected amino, a protected lower alkylamino, hydroxy or lower alkoxy, R2 is hydrogen, acyloxy, pyridium or a heterocyclicthio group which may have suitable substituent(s), R3 is carboxy or its derivative, A is carbonyl, hydroxy(lower)alkylene or a protected hydroxy(lower)alkylene and R4 is hydrogen or halogen, or R2 and R3 are linked together to represent a group of the formula -COO-, this divisional application being directed to intermediate compounds of the formula:

公开(公告)号：DK276582A

公开(公告)日：1982-12-23

申请号：DK276582

申请日：1982-06-18

Applicant: FUJISAWA PHARMACEUTICAL CO

Inventor： TERAJI T ,  SAKANE K ,  GOTO J

IPC: C07D213/61 ,  C07D213/70 ,  C07D213/73 ,  C07D285/08 ,  C07D501/36 ,  C07D

Abstract: New cephem compounds of the formula: … … wherein… R is amino or a protected amino group;… R is hydrogen, lower aliphatic hydrocarbon group which may be substituted with suitable substituent(s), cyclo(lower)alkyl, or cyclo(lower)alkenyl;… R is lower alkyl which mad be substituted with suitable substituents(s);… R is hydrogen, lower alkyl or amino; and R is hydrogen or lower alkyl; and… pharmaceutically acceptable salts thereof, and processes for their preparation and a pharmaceutical antibacterial composition comprising them in association with a pharmaceutical antibacterial composition comprising a compound of claim 1 in association with a pharmaceutically acceptable, substantially non-toxic carrier or excipient.

公开(公告)号：AU7144281A

公开(公告)日：1981-12-24

申请号：AU7144281

申请日：1981-06-09

Applicant: FUJISAWA PHARMACEUTICAL CO

Inventor： TERAJI T ,  SAKANE K ,  GOTO J

IPC: C07D501/46 ,  A61K20060101 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D20060101 ,  C07D501/24