公开(公告)号：US20220011558A1

公开(公告)日：2022-01-13

申请号：US17482678

申请日：2021-09-23

Applicant: Femtonics Kft.

Inventor： Balazs ROZSA ,  Gergely KATONA ,  Pal MAAK ,  Mate VERESS ,  Andras FEHER ,  Gergely SZALAY ,  Peter MATYAS

IPC: G02B21/00 ,  G01N21/64 ,  G06T5/50

Abstract: The invention relates to a method for correcting motion artifacts of in vivo fluorescence measurements using a 3D laser scanning microscope containing two pairs of orthogonally arranged acousto-optic deflectors, the method comprising: selecting a region of interest, selecting a plurality of guiding points along the region of interest, extending the guiding points to objects selected from scanning lines and/or surface elements and/or volume elements which, together, substantially cover the region of interest, repeatedly scanning the objects by generating continuous drifts to cover the objects, projecting the obtained scanning data to frames and obtaining a time series of the frames, correcting motion artifacts by shifting the data of the successive frames with respect to each other so as to maximize fluorescence cross correlation between the data of the frames.

公开(公告)号：US20210318590A1

公开(公告)日：2021-10-14

申请号：US17268199

申请日：2019-08-14

Applicant: Femtonics Kft.

Inventor： Gergely KATONA ,  András FEHÉR ,  Máté VERESS ,  Pál MAÁK ,  Gergely SZALAY ,  Balázs CHIOVINI ,  Zoltán SZADAI ,  Linda SULCZ-JUDÁK ,  Balázs József RÓZSA

IPC: G02F1/33 ,  G01N21/64

Abstract: The object of the invention relates to a method for scanning with an optical beam (50) using a first acousto-optic deflector (15, 15′) having an optical axis along a Z-axis and at least one acousto-optic crystal layer (14), involving directing the optical beam (50) in the first acousto-optic deflector (15, 15′), and deflecting the optical beam (50) along an X-axis perpendicular to the Z-axis by means of the first acousto-optic deflector (15, 15), during which generating a plurality of acoustic chirp signals (30) in the at least one acousto-optic crystal layer (14) of the acousto-optic deflector (15, 15′) by—generating a first acoustic chirp signal (30a) having a duration of τ in the acousto-optic crystal layer (14), then—generating a second acoustic chirp signal (30b) in the acousto-optic crystal layer (14) within a τ period of time counted from the start of the generation of the first acoustic chirp signal (30a).

公开(公告)号：US20220295743A1

公开(公告)日：2022-09-22

申请号：US17626700

申请日：2020-07-09

Applicant: FEMTONICS KFT.

Inventor： Gergely DOBOS ,  Domonkos Péter PINKE ,  Tamás TOMPA ,  Pál MAÁK ,  Máté MAROSI ,  Gergely KATONA ,  Gergely SZALAY ,  Balázs RÓZSA

IPC: A01K15/02 ,  G02B27/00 ,  G06F3/01 ,  G06F1/16

Abstract: The present invention relates to a virtual reality simulator (10) for small laboratory animals (100), in particular rodents, which comprises a head clamping mechanism (20) for securing the laboratory animal (100) and virtual reality glasses (40) with two wings (30), each of the wings (30) having a display (34) and a lens system (36) spaced therefrom and connected together by a light barrier cover (32), and the virtual reality glasses (40) are configured to allow the two wings (30) to align with each of the eyes (101) of the laboratory animal (100), respectively. The invention further relates to a method applying such a simulator (10).

公开(公告)号：US20190285865A1

公开(公告)日：2019-09-19

申请号：US16290238

申请日：2019-03-01

Applicant: Femtonics Kft.

Inventor： Balazs ROZSA ,  Gergely KATONA ,  Pal MAAK ,  Mate VERESS ,  Andras FEHER ,  Gergely SZALAY ,  Peter MATYAS

IPC: G02B21/00 ,  G06K9/32

Abstract: The invention relates to a method for scanning along a substantially straight line (3D line) lying at an arbitrary direction in a 3D space with a given speed using a 3D laser scanning microscope having a first pair of acousto-optic deflectors deflecting a laser beam in the x-z plane (x axis deflectors) and a second pair of acousto-optic deflectors deflecting the laser beam in the y-z plane (y axis deflectors) for focusing the laser beam in 3D.The invention further relates to a method for scanning a region of interest with a 3D laser scanning microscope having acousto-optic deflectors for focusing a laser beam within a 3D space defined by an optical axis (Z) of the microscope and X, Y axes that are perpendicular to the optical axis and to each other