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1.发明专利
公开(公告)号：SI2855687T1
公开(公告)日：2020-09-30
申请号：SI201331751
申请日：2013-06-03
Applicant: GENOMATICA INC
Inventor： BURK MARK J , PHARKYA PRITI , BURGARD ANTHONY P , VAN DIEN STEPHEN J , OSTERHOUT ROBIN E , TRAWICK JOHN D , KUCHINSKAS MICHAEL P , STEER BRIAN
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Patent Agency Ranking2.发明专利
公开(公告)号：MY187966A
公开(公告)日：2021-11-02
申请号：MYPI2015703784
申请日：2014-04-25
Applicant: GENOMATICA INC
Inventor： PHARKYA PRITI , BURGARD ANTHONY P , VAN DIEN STEPHEN J , OSTERHOUT ROBIN E , BURK MARK J , TRAWICK JOHN D , KUCHINSKAS MICHAEL P , STEER BRIAN , ANDRAE STEFAN , SHAH AMIT
Abstract: The invention provides non-naturally occurring microbial organisms having a 4- hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, 4-hydroxybutanal, 4- hydroxybutyryl-CoA and/or putrescine pathway and being capable of producing 4- hydroxybutyrate, wherein the microbial organism comprises one or more genetic modifications. The invention additionally provides methods of producing 4- hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, 4-hydroxybutanal, 4- hydroxybutyryl-CoA and/or putrescine or related products using the microbial organisms. (FIG. 1)
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3.发明申请MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS 审中-公开用于生产4-羟基丁酸酯，1,4-丁二醇和相关化合物的微生物和方法
公开(公告)号：WO2013184602A3
公开(公告)日：2014-01-30
申请号：PCT/US2013043954
申请日：2013-06-03
Applicant: GENOMATICA INC , BURK MARK J
Inventor： BURK MARK J , PHARKYA PRITI , BURGARD ANTHONY P , VAN DIEN STEPHEN J , OSTERHOUT ROBIN E , TRAWICK JOHN D , KUCHINSKAS MICHAEL P , STEER BRIAN
CPC classification number: C12N1/20 , C07C31/207 , C07C59/01 , C08G18/284 , C08G18/3206 , C08G63/06 , C08G63/16 , C08G63/181 , C08G69/02 , C12N9/18 , C12N15/52 , C12N15/63 , C12P7/18 , C12P7/42 , C12Y301/01 , Y02P20/52
Abstract: The invention provides non-naturally occurring microbial organisms having a 4- hydroxybutyrate, 1,4-butanediol, or other product pathway and being capable of producing 4- hydroxybutyrate, 1,4-butanediol, or other product, wherein the microbial organism comprises one or more genetic modifications. The invention additionally provides methods of producing 4- hydroxybutyrate, 1,4-butanediol, or other product or related products using the microbial organisms.
Abstract translation: 本发明提供具有4-羟基丁酸酯，1,4-丁二醇或其它产物途径的非天然存在的微生物生物，并能够生产4-羟基丁酸酯，1,4-丁二醇或其它产品，其中微生物包含一种 或更多遗传修饰。 本发明另外提供了使用微生物生物制备4-羟基丁酸酯，1,4-丁二醇或其它产品或相关产品的方法。
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4.发明申请MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS 审中-公开用于生产4-羟基丁酸酯，1,4-丁二醇和相关化合物的微生物和方法
公开(公告)号：WO2014176514A3
公开(公告)日：2015-01-15
申请号：PCT/US2014035475
申请日：2014-04-25
Applicant: GENOMATICA INC
Inventor： PHARKYA PRITI , BURGARD ANTHONY P , VAN DIEN STEPHEN J , OSTERHOUT ROBIN E , BURK MARK J , TRAWICK JOHN D , KUCHINSKAS MICHAEL P , STEER BRIAN
CPC classification number: C12P7/18 , C07C31/207 , C07C47/19 , C07C211/09 , C07D307/33 , C12N1/20 , C12N9/0006 , C12N9/13 , C12N15/52 , C12P7/24 , C12P7/42 , C12P7/62 , C12P13/001 , C12P13/005 , C12P17/04 , C12P19/32 , C12Y208/03
Abstract: The invention provides non-naturally occurring microbial organisms having a 4-hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA and/or putrescine pathway and being capable of producing 4-hydroxybutyrate, wherein the microbial organism comprises one or more genetic modifications. The invention additionally provides methods of producing 4-hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA and/or putrescine or related products using the microbial organisms.
Abstract translation: 本发明提供具有4-羟基丁酸酯，γ-丁内酯，1,4-丁二醇，4-羟基丁醛，4-羟基丁酰辅酶A和/或腐胺途径并且能够产生4-羟基丁酸酯的非天然存在的微生物，其中 微生物生物体包含一种或多种遗传修饰。 本发明另外提供使用微生物生产4-羟基丁酸酯，γ-丁内酯，1,4-丁二醇，4-羟基丁醛，4-羟基丁酰-CoA和/或腐胺或相关产品的方法。
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5.发明公开MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS 审中-公开微生物及其制备方法4-羟基丁酸酯，1,4-丁二醇和相关链接
公开(公告)号：EP2855687A4
公开(公告)日：2016-09-14
申请号：EP13800646
申请日：2013-06-03
Applicant: GENOMATICA INC
Inventor： BURK MARK J , PHARKYA PRITI , BURGARD ANTHONY P , VAN DIEN STEPHEN J , OSTERHOUT ROBIN E , TRAWICK JOHN D , KUCHINSKAS MICHAEL P , STEER BRIAN
CPC classification number: C12N1/20 , C07C31/207 , C07C59/01 , C08G18/284 , C08G18/3206 , C08G63/06 , C08G63/16 , C08G63/181 , C08G69/02 , C12N9/18 , C12N15/52 , C12N15/63 , C12P7/18 , C12P7/42 , C12Y301/01 , Y02P20/52
Abstract: The invention provides non-naturally occurring microbial organisms having a 4-hydroxybutyrate pathway and being capable of producing 4-hydroxybutyrate, wherein the microbial organism comprises one or more genetic modifications. The invention additionally provides methods of producing 4-hydroxybutyrate or related products using the microbial organisms.
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6.发明公开MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS 审中-公开用于生产4-羟基丁酸酯，1,4- and二醇及相关化合物的微生物和方法
公开(公告)号：EP2989113A4
公开(公告)日：2016-11-30
申请号：EP14788673
申请日：2014-04-25
Applicant: GENOMATICA INC
Inventor： PHARKYA PRITI , BURGARD ANTHONY P , VAN DIEN STEPHEN J , OSTERHOUT ROBIN E , BURK MARK J , TRAWICK JOHN D , KUCHINSKAS MICHAEL P , STEER BRIAN , ANDRAE STEFAN , SHAH AMIT
CPC classification number: C12P7/18 , C07C31/207 , C07C47/19 , C07C211/09 , C07D307/33 , C12N1/20 , C12N9/0006 , C12N9/13 , C12N15/52 , C12P7/24 , C12P7/42 , C12P7/62 , C12P13/001 , C12P13/005 , C12P17/04 , C12P19/32 , C12Y208/03
Abstract: The invention provides non-naturally occurring microbial organisms having a 4-hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA and/or putrescine pathway and being capable of producing 4-hydroxybutyrate, wherein the microbial organism comprises one or more genetic modifications. The invention additionally provides methods of producing 4-hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA and/or putrescine or related products using the microbial organisms.
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