公开(公告)号：CA2667702A1

公开(公告)日：2008-04-24

申请号：CA2667702

申请日：2007-10-18

Applicant: HARVARD COLLEGE

Inventor： MIRICA KATHERINE A ,  LIU YANYAN ,  CARRILHO EMANUEL ,  MARTINEZ ANDRES W ,  BUTTE MANISH J ,  VELLA SARAH JANE ,  WHITESIDES GEORGE M ,  SINDI HAYAT ,  WONG AMY ,  PHILLIPS SCOTT T ,  THOMAS SAMUEL

IPC: G01N33/558

Abstract: Embodiments of the invention provide lateral flow and flow-through bioass ay devices based on patterned porous media, methods of making same, and meth ods of using same. Under one aspect, an assay device includes a porous, hydr ophilic medium; a fluid impervious barrier comprising polymerized photoresis t, the barrier substantially permeating the thickness of the porous, hydroph ilic medium and defining a boundary of an assay region within the porous, hy drophilic medium; and an assay reagent in the assay region.

公开(公告)号：AU2007310987A1

公开(公告)日：2008-04-24

申请号：AU2007310987

申请日：2007-10-18

Applicant: HARVARD COLLEGE

Inventor： THOMAS SAMUEL ,  WHITESIDES GEORGE M ,  WONG AMY ,  CARRILHO EMANUEL ,  MARTINEZ ANDRES W ,  SINDI HAYAT ,  LIU YANYAN ,  PHILLIPS SCOTT T ,  MIRICA KATHERINE A ,  BUTTE MANISH J ,  VELLA SARAH JANE

IPC: G01N33/558

公开(公告)号：CA2667702C

公开(公告)日：2016-06-14

申请号：CA2667702

申请日：2007-10-18

Applicant: HARVARD COLLEGE

Inventor： WHITESIDES GEORGE M ,  PHILLIPS SCOTT T ,  MARTINEZ ANDRES W ,  BUTTE MANISH J ,  WONG AMY ,  THOMAS SAMUEL ,  SINDI HAYAT ,  VELLA SARAH JANE ,  CARRILHO EMANUEL ,  MIRICA KATHERINE A ,  LIU YANYAN

IPC: G01N33/558

Abstract: Embodiments of the invention provide lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same. Under one aspect, an assay device includes a porous, hydrophilic medium; a fluid impervious barrier comprising polymerized photoresist, the barrier substantially permeating the thickness of the porous, hydrophilic medium and defining a boundary of an assay region within the porous, hydrophilic medium; and an assay reagent in the assay region.

公开(公告)号：AU2007310987B2

公开(公告)日：2014-01-09

申请号：AU2007310987

申请日：2007-10-18

Applicant: HARVARD COLLEGE

Inventor： VELLA SARAH JANE ,  MARTINEZ ANDRES W ,  WONG AMY ,  MIRICA KATHERINE A ,  WHITESIDES GEORGE M ,  BUTTE MANISH J ,  SINDI HAYAT ,  PHILLIPS SCOTT T ,  CARRILHO EMANUEL ,  THOMAS SAMUEL ,  LIU YANYAN

IPC: G01N33/558

Abstract: Embodiments of the invention provide lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same. Under one aspect, an assay device includes a porous, hydrophilic medium; a fluid impervious barrier comprising polymerized photoresist, the barrier substantially permeating the thickness of the porous, hydrophilic medium and defining a boundary of an assay region within the porous, hydrophilic medium; and an assay reagent in the assay region.

公开(公告)号：BRPI0718473A2

公开(公告)日：2013-12-03

申请号：BRPI0718473

申请日：2007-10-18

Applicant: HARVARD COLLEGE

Inventor： WHITESIDES GEORGE M ,  PHILLIPS SCOTT T ,  MARTINEZ ANDRES W ,  BUTTE MANISH J ,  WONG AMY ,  THOMAS SAMUEL ,  SINDI HAYAT ,  VELLA SARAH JANE ,  MIRICA KATHERINE A ,  LIU YANYAN ,  CARRILHO EMANUEL

IPC: G01N33/558

公开(公告)号：WO2008049083A3

公开(公告)日：2009-03-12

申请号：PCT/US2007081848

申请日：2007-10-18

Applicant: HARVARD COLLEGE ,  WHITESIDES GEORGE M ,  PHILLIPS SCOTT T ,  MARTINEZ ANDRES W ,  BUTTE MANISH J ,  WONG AMY ,  THOMAS SAMUEL ,  SINDI HAYAT ,  VELLA SARAH JANE ,  CARRILHO EMANUEL ,  MIRICA KATHERINE A ,  LIU YANYAN

Inventor： WHITESIDES GEORGE M ,  PHILLIPS SCOTT T ,  MARTINEZ ANDRES W ,  BUTTE MANISH J ,  WONG AMY ,  THOMAS SAMUEL ,  SINDI HAYAT ,  VELLA SARAH JANE ,  CARRILHO EMANUEL ,  MIRICA KATHERINE A ,  LIU YANYAN

IPC: G01N33/558

CPC classification number: G01N33/558

Abstract: Embodiments of the invention provide lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same. Under one aspect, an assay device includes a porous, hydrophilic medium; a fluid impervious barrier comprising polymerized photoresist, the barrier substantially permeating the thickness of the porous, hydrophilic medium and defining a boundary of an assay region within the porous, hydrophilic medium; and an assay reagent in the assay region.

Abstract translation: 本发明的实施方案提供了基于图案化多孔介质的横向流动和流通生物测定装置，其制备方法及其使用方法。 在一个方面，测定装置包括多孔亲水介质; 包含聚合的光致抗蚀剂的流体不透过屏障，所述屏障基本上渗透所述多孔亲水介质的厚度，并且限定所述多孔亲水介质内的测定区域的边界; 和测定区域中的测定试剂。