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公开(公告)号:ES2536206T3
公开(公告)日:2015-05-21
申请号:ES09715573
申请日:2009-02-09
Applicant: HISAMITSU PHARMACEUTICAL CO
Inventor: YAMAMOTO NAOKI , MORIMOTO KUMI , TAKEUCHI AKIO , ISHIGAKI KENJI
IPC: A61K9/70 , A61K31/4985
Abstract: Parche medicinal que comprende como agente farmaceutico vareniclina en su forma de base libre, un material de base adhesivo, un agente de pegajosidad, un solubilizante y una sal de metal, en el que vareniclina en su forma de base libre y la sal de metal pueden obtenerse mediante reaccion de neutralizacion entre la sal de adicion de acido del agente farmaceutico e hidroxido de metal, que se anade en una cantidad para convertir la totalidad o una parte del agente farmaceutico en la base libre, el material de base adhesivo es un material de base adhesivo de caucho y el agente de pegajosidad es un agente de pegajosidad no basado en colofonia seleccionado del grupo que consiste en resinas de hidrocarburo alifatico y resinas de hidrocarburo aliciclico, y el solubilizante se selecciona del grupo que consiste en propilenglicol y dipropilenglicol.
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公开(公告)号:ES2753423T3
公开(公告)日:2020-04-08
申请号:ES14814482
申请日:2014-06-17
Applicant: HISAMITSU PHARMACEUTICAL CO
Inventor: YAMAMOTO NAOKI , OGURA MAKOTO
IPC: A61M37/00
Abstract: Aplicador (10,30) para aplicar microagujas (2) a la piel, que comprende: una porción resistiva (14,34) configurada para aplicar resistencia contra el movimiento de una lámina de microagujas (20) que tiene una pluralidad de microagujas (22) formadas a lo largo de una superficie principal de la lámina (20); y una porción de flexión (15, 35) configurada para flexionar la lámina de microagujas (20) que atraviesa la porción resistiva (14, 34) para elevar las microagujas (22) desde la superficie principal, caracterizado por que el diámetro de la porción de flexión (15,35) es de 0,1 a 4 mm y la altura de cada microaguja (22) es de 10 a 1000 μm.
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公开(公告)号:EP3011992A4
公开(公告)日:2017-03-15
申请号:EP14813654
申请日:2014-06-17
Applicant: HISAMITSU PHARMACEUTICAL CO INC
Inventor: YAMAMOTO NAOKI , OGURA MAKOTO
CPC classification number: A61M37/0015 , A61M25/002 , A61M35/00 , A61M37/00 , A61M2025/0266 , A61M2037/0023
Abstract: An applicator of one aspect for applying a sheet member to skin includes a body having a bottom surface facing the skin and a first guide configured to guide the sheet member to a space between the skin and the bottom surface, in which the sheet member is applied to the skin after being folded in the space.
Abstract translation: 一种用于将片状部件应用于皮肤的施用器,包括:具有面向皮肤的底面的主体;以及被构造成将片状部件引导至皮肤与底面之间的空间的第一引导件,其中片状部件被施加 在被折叠在空间后到达皮肤。
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公开(公告)号:EP2258369A4
公开(公告)日:2011-05-04
申请号:EP09715573
申请日:2009-02-09
Applicant: HISAMITSU PHARMACEUTICAL CO
Inventor: YAMAMOTO NAOKI , MORIMOTO KUMI , TAKEUCHI AKIO , ISHIGAKI KENJI
CPC classification number: A61K31/4985 , A61K9/7061
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公开(公告)号:EP3111987A4
公开(公告)日:2017-10-11
申请号:EP15755798
申请日:2015-02-19
Applicant: HISAMITSU PHARMACEUTICAL CO INC
Inventor: YAMAMOTO NAOKI , OGURA MAKOTO
CPC classification number: A61K9/0021 , A61M37/0015 , A61M2037/0023 , A61M2037/0053 , A61M2037/0061
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公开(公告)号:EP3042690A4
公开(公告)日:2017-04-26
申请号:EP14843133
申请日:2014-09-03
Applicant: HISAMITSU PHARMACEUTICAL CO INC
Inventor: YAMAMOTO NAOKI , OGURA MAKOTO
IPC: A61M37/00
CPC classification number: A61M37/0015 , A61M2037/0023 , A61M2037/0038 , A61M2037/0053
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公开(公告)号:EP2859910A4
公开(公告)日:2016-06-08
申请号:EP13803698
申请日:2013-06-11
Applicant: HISAMITSU PHARMACEUTICAL CO
Inventor: KOMINAMI KAZUYA , NISHIMURA SHINPEI , TOKUMOTO SEIJI , OGURA MAKOTO , MATSUDO TOSHIYUKI , YAMAMOTO NAOKI
CPC classification number: A61M37/0015 , A61M37/0092 , A61M2037/0007 , A61M2037/0023 , A61M2037/0061 , A61N1/325 , A61N2/002 , A61N2/004
Abstract: A microneedle sheet according to an embodiment comprises a plurality of microneedles formed on a sheet substantially along a principal surface of the sheet. The sheet is bent to raise the microneedles from the principal surface, and the raised microneedles pierce a skin.
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公开(公告)号:EP3216484A4
公开(公告)日:2018-07-25
申请号:EP15866287
申请日:2015-12-04
Applicant: HISAMITSU PHARMACEUTICAL CO INC
Inventor: OGURA MAKOTO , YAMAMOTO NAOKI , KUMON TAKASHI
IPC: A61M37/00
CPC classification number: A61M37/0015 , A61M37/00 , A61M2037/0023
Abstract: A microneedle device system includes a microneedle device having a sheet-like microneedle having a sheet in which one surface is a skin contact surface and the other surface is a rear surface, and in which a plurality of microneedles are formed substantially along a surface of the sheet, and in which the microneedles in the skin piercing region are raised from the skin contact surface so as to be capable of piercing skin if the sheet is bent in a thickness direction, an adhesive layer that is disposed on the sheet-like microneedle, and a liner that is attached to the adhesive layer so as to be releasable therefrom, and an auxiliary tool having a bending portion which bends the microneedle device in the thickness direction, and on which the microneedle device is mounted so as to be movable along the bending portion.
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公开(公告)号:EP3011993A4
公开(公告)日:2017-03-08
申请号:EP14814482
申请日:2014-06-17
Applicant: HISAMITSU PHARMACEUTICAL CO INC
Inventor: YAMAMOTO NAOKI , OGURA MAKOTO
IPC: A61M37/00
CPC classification number: A61M37/0015 , A61M2037/0023
Abstract: An applicator of one aspect for applying microneedles to skin includes a resistive portion configured to apply resistance against movement of a microneedle sheet having the plurality of microneedles formed along a main surface of the sheet, and a bending portion configured to bend the microneedle sheet passed through the resistive portion to raise the microneedle from the main surface.
Abstract translation: 用于将微针施加至皮肤的一个方面的施加器包括电阻部分,该电阻部分被配置为对具有沿着片材的主表面形成的多个微针的微针片材的移动施加阻力,以及弯曲部分,该弯曲部分被配置为弯曲穿过的微针片材 电阻部分使微针从主表面升起。
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