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公开(公告)号：ZA89121B
公开(公告)日：1989-09-27
申请号：ZA89121
申请日：1989-01-06
Applicant: HOECHST AG
Inventor： BAADER EKKEHARD , EKKEHARD BAADER , JENDRALLA HEINER , HEINER JENDRALLA , BELA KEREKJARTO , BECK GERHARD , GERHARD BECK , KEREKJARTO BELA
IPC: A61K20060101 , A61K31/50 , A61P3/06 , A61P9/10 , C07C43/23 , C07C45/30 , C07C45/63 , C07C49/04 , C07C49/16 , C07C49/223 , C07C49/567 , C07C49/76 , C07C49/782 , C07C49/80 , C07C49/813 , C07C49/84 , C07D20060101 , C07D237/08 , C07D237/24 , C07D405/06 , C07D , A61K
Abstract: 3,5-Dihydroxycarboxylic acids and their derivatives of the formula I and the corresponding lactones of the formula II in which R , R , R , R and X-Y have the meanings given, process for the preparation of these compounds, their use as medicines and pharmaceutical compositions are described. Novel intermediates for the preparation of the compounds of the formulae I and II are additionally described.
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公开(公告)号：ZA9000394B
公开(公告)日：1991-04-24
申请号：ZA9000394
申请日：1990-01-19
Applicant: HOECHST AG
Inventor： HEITZ WALTER , WALTER HEITZ , FISCHER THOMAS , THOMAS FISCHER , KEREKJARTO BELA , BELA KEREKJARTO
IPC: A23L3/3481 , A23L3/3535 , A61K31/785 , A61P3/06 , C08G73/02 , C08G73/04 , C08G
CPC classification number: C08G73/0213 , A23L3/3481 , A23L3/3535 , A61K31/785
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公开(公告)号：ZA882851B
公开(公告)日：1988-12-28
申请号：ZA882851
申请日：1988-04-22
Applicant: HOECHST AG
Inventor： LANG HANS-JOCHEN , HANS-JOCHEN LANG , KEREKJARTO BELA , BELA KEREKJARTO , HROPOT MAX , MAX HROPOT , GRANZER ERNOLD , ERNOLD GRANZER
IPC: C07D207/26 , C07D207/273 , C07D207/27 , C07D , C07C , A61K
Abstract: Compounds of the formula I I with R1 equal to H or (cyclo)alk(en)yl, R2 equal to H or alkyl, R3 equal to alkyl, R4/R5 equal to H, alkyl or acyl, and Y equal to H, alkyl, CF3 or Hal, are described, as are processes for the preparation thereof. They are effective diuretics and antihypertensive agents with a lipid-lowering action.
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公开(公告)号：ZA901189B
公开(公告)日：1990-10-31
申请号：ZA901189
申请日：1990-02-16
Applicant: HOECHST AG
Inventor： LANG HANS-JOCHEN , HANS-JOCHEN LANG , GRANZER ERNOLD , ERNOLD GRANZER , KEREKJARTO BELA , BELA KEREKJARTO
IPC: A61K31/18 , A61P3/06 , C07C303/38 , C07C311/21 , C07C311/29 , C07C311/44 , C07C317/10 , C07C317/14 , C07C323/67 , C07C , A61K
Abstract: Compounds of the formula I I where R1 to R5 have the meaning indicated, a process for their preparation and their use as medicaments are described. They are effective lipid-lowering agents with antioxidative properties from the benzenesulfonamide series. They do not have hypotensive and diuretic properties.
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公开(公告)号：ZA8900121B
公开(公告)日：1989-09-27
申请号：ZA8900121
申请日：1989-01-06
Applicant: HOECHST AG
Inventor： BAADER EKKEHARD , EKKEHARD BAADER , JENDRALLA HEINER , HEINER JENDRALLA , KEREKJARTO BELA , BELA KEREKJARTO , BECK GERHARD , GERHARD BECK
IPC: A61K20060101 , A61K31/50 , A61P3/06 , A61P9/10 , C07C43/23 , C07C45/30 , C07C45/63 , C07C49/04 , C07C49/16 , C07C49/223 , C07C49/567 , C07C49/76 , C07C49/782 , C07C49/80 , C07C49/813 , C07C49/84 , C07D20060101 , C07D237/08 , C07D237/24 , C07D405/06 , C07D , A61K
CPC classification number: C07D405/06 , C07C43/23 , C07C45/305 , C07C45/63 , C07C49/04 , C07C49/16 , C07C49/223 , C07C49/567 , C07C49/76 , C07C49/782 , C07C49/80 , C07C49/813 , C07C49/84 , C07D237/08 , C07D237/24
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Patent Agency Ranking
公开(公告)号：ZA8802851B
公开(公告)日：1988-12-28
申请号：ZA8802851
申请日：1988-04-22
Applicant: HOECHST AG
Inventor： LANG HANS-JOCHEN , HANS-JOCHEN LANG , KEREKJARTO BELA , BELA KEREKJARTO , HROPOT MAX , MAX HROPOT , GRANZER ERNOLD , ERNOLD GRANZER
IPC: C07D207/27 , C07D207/26 , C07D207/273 , C07D , A61K , C07C
CPC classification number: C07D207/273
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公开(公告)号：ZA8909100B
公开(公告)日：1990-08-29
申请号：ZA8909100
申请日：1989-11-29
Applicant: HOECHST AG
Inventor： LANG HANS-JOCHEN , HANS-JOCHEN LANG , GRANZER ERNOLD , ERNOLD GRANZER , HROPOT MAX , MAX HROPOT , KEREKJARTO BELA , BELA KEREKJARTO
IPC: A61K31/18 , A61K31/40 , A61K31/403 , A61K31/4035 , A61P3/06 , A61P9/10 , C07C311/21 , C07D209/48 , C07D , A61K , C07C
CPC classification number: C07D209/48
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公开(公告)号：ZA90394B
公开(公告)日：1991-04-24
申请号：ZA90394
申请日：1990-01-19
Applicant: HOECHST AG
Inventor： HEITZ WALTER , WALTER HEITZ , FISCHER THOMAS , THOMAS FISCHER , KEREKJARTO BELA , BELA KEREKJARTO
IPC: A23L3/3481 , A23L3/3535 , A61K31/785 , A61P3/06 , C08G73/02 , C08G73/04 , C08G
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公开(公告)号：ZA9001189B
公开(公告)日：1990-10-31
申请号：ZA9001189
申请日：1990-02-16
Applicant: HOECHST AG
Inventor： LANG HANS-JOCHEN , HANS-JOCHEN LANG , GRANZER ERNOLD , ERNOLD GRANZER , KEREKJARTO BELA , BELA KEREKJARTO
IPC: A61K31/18 , A61P3/06 , C07C303/38 , C07C311/21 , C07C311/29 , C07C311/44 , C07C317/10 , C07C317/14 , C07C323/67 , C07C , A61K
CPC classification number: C07C323/67 , C07C311/21 , C07C311/29 , C07C317/14 , Y10S514/824 , Y10S514/869
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公开(公告)号：ZA899100B
公开(公告)日：1990-08-29
申请号：ZA899100
申请日：1989-11-29
Applicant: HOECHST AG
Inventor： LANG HANS-JOCHEN , HANS-JOCHEN LANG , GRANZER ERNOLD , ERNOLD GRANZER , HROPOT MAX , MAX HROPOT , KEREKJARTO BELA , BELA KEREKJARTO
IPC: A61K31/18 , A61K31/40 , A61K31/403 , A61K31/4035 , A61P3/06 , A61P9/10 , C07C311/21 , C07D209/48 , C07D , A61K , C07C
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