公开(公告)号：AU621691B2

公开(公告)日：1992-03-19

申请号：AU4561589

申请日：1989-11-29

Applicant: HOECHST AG

Inventor： LANG HANS-JOCHEN ,  GRANZER ERNOLD ,  HROPOT MAX ,  KEREKJARTO BELA

IPC: A61K31/18 ,  A61K31/40 ,  A61K31/403 ,  A61K31/4035 ,  A61P3/06 ,  A61P9/10 ,  C07C311/21 ,  C07D209/48

公开(公告)号：PH26148A

公开(公告)日：1992-03-18

申请号：PH38012

申请日：1989-01-06

Applicant: HOECHST AG

Inventor： BAADER EKKEHARD ,  JENDRALLA HLINER ,  BECK GERHARD ,  KEREKJARTO BELA

IPC: A61K20060101 ,  A61K31/50 ,  A61P3/06 ,  A61P9/10 ,  C07C43/23 ,  C07C45/30 ,  C07C45/63 ,  C07C49/04 ,  C07C49/16 ,  C07C49/223 ,  C07C49/567 ,  C07C49/76 ,  C07C49/782 ,  C07C49/80 ,  C07C49/813 ,  C07C49/84 ,  C07D20060101 ,  C07D237/08 ,  C07D237/24 ,  C07D405/06 ,  C07D237/00

Abstract: 3,5-Dihydroxycarboxylic acids and their derivatives of the formula I and the corresponding lactones of the formula II in which R , R , R , R and X-Y have the meanings given, process for the preparation of these compounds, their use as medicines and pharmaceutical compositions are described. Novel intermediates for the preparation of the compounds of the formulae I and II are additionally described.

公开(公告)号：ZA8909100B

公开(公告)日：1990-08-29

申请号：ZA8909100

申请日：1989-11-29

Applicant: HOECHST AG

Inventor： LANG HANS-JOCHEN ,  HANS-JOCHEN LANG ,  GRANZER ERNOLD ,  ERNOLD GRANZER ,  HROPOT MAX ,  MAX HROPOT ,  KEREKJARTO BELA ,  BELA KEREKJARTO

IPC: A61K31/18 ,  A61K31/40 ,  A61K31/403 ,  A61K31/4035 ,  A61P3/06 ,  A61P9/10 ,  C07C311/21 ,  C07D209/48 ,  C07D ,  A61K ,  C07C

CPC classification number: C07D209/48

公开(公告)号：AU4985190A

公开(公告)日：1990-08-23

申请号：AU4985190

申请日：1990-02-16

Applicant: HOECHST AG

Inventor： LANG HANS-JOCHEN ,  GRANZER ERNOLD ,  KEREKJARTO BELA

IPC: A61K31/18 ,  A61P3/06 ,  C07C303/38 ,  C07C311/21 ,  C07C311/29 ,  C07C311/44 ,  C07C317/10 ,  C07C317/14 ,  C07C323/67 ,  C07C311/39 ,  C07C321/28 ,  C07C315/04 ,  C07C319/20 ,  A61K31/10

Abstract: Compounds of the formula I I where R1 to R5 have the meaning indicated, a process for their preparation and their use as medicaments are described. They are effective lipid-lowering agents with antioxidative properties from the benzenesulfonamide series. They do not have hypotensive and diuretic properties.

公开(公告)号：PT92441A

公开(公告)日：1990-05-31

申请号：PT9244189

申请日：1989-11-29

Applicant: HOECHST AG

Inventor： LANG HANS-JOCHEN ,  GRANZER ERNOLD ,  KEREKJARTO BELA ,  HROPOT MAX

IPC: A61K31/18 ,  A61K31/40 ,  A61K31/403 ,  A61K31/4035 ,  A61P3/06 ,  A61P9/10 ,  C07C311/21 ,  C07D209/48

公开(公告)号：NO900279D0

公开(公告)日：1990-01-19

申请号：NO900279

申请日：1990-01-19

Applicant: HOECHST AG

Inventor： HEITZ WALTER ,  FISCHER THOMAS ,  KEREKJARTO BELA

IPC: A23L3/3481 ,  A23L3/3535 ,  A61K31/785 ,  A61P3/06 ,  C08G73/02 ,  C08G73/04 ,  C08G

公开(公告)号：NO890062L

公开(公告)日：1989-07-10

申请号：NO890062

申请日：1989-01-06

Applicant: HOECHST AG

Inventor： BAADER EKKEHARD ,  JENDRALLA HEINER ,  KEREKJARTO BELA ,  BECK GERHARD

IPC: A61K20060101 ,  A61K31/50 ,  A61P3/06 ,  A61P9/10 ,  C07C43/23 ,  C07C45/30 ,  C07C45/63 ,  C07C49/04 ,  C07C49/16 ,  C07C49/223 ,  C07C49/567 ,  C07C49/76 ,  C07C49/782 ,  C07C49/80 ,  C07C49/813 ,  C07C49/84 ,  C07D20060101 ,  C07D237/08 ,  C07D237/24 ,  C07D405/06

Abstract: 3,5-Dihydroxycarboxylic acids and their derivatives of the formula I and the corresponding lactones of the formula II in which R , R , R , R and X-Y have the meanings given, process for the preparation of these compounds, their use as medicines and pharmaceutical compositions are described. Novel intermediates for the preparation of the compounds of the formulae I and II are additionally described.

公开(公告)号：NO883072A

公开(公告)日：1989-01-11

申请号：NO883072

申请日：1988-07-08

Applicant: HOECHST AG

Inventor： JENDRALLA HEINER ,  BECK GERHARD ,  BAADER EKKEHARD ,  KEREKJARTO BELA

IPC: A61K31/40 ,  A61K31/4025 ,  A61P3/06 ,  C07D207/32 ,  C07D207/337 ,  C07D207/34 ,  C07D405/06 ,  C07D207/00 ,  C07D405/00

CPC classification number: C07D207/337 ,  C07D405/06

公开(公告)号：DK384288A

公开(公告)日：1989-01-11

申请号：DK384288

申请日：1988-07-08

Applicant: HOECHST AG

Inventor： JENDRALLA HEINER ,  BECK GERHARD ,  BAADER EKKEHARD ,  KEREKJARTO BELA

IPC: A61K31/40 ,  A61K31/4025 ,  A61P3/06 ,  C07D207/32 ,  C07D207/333 ,  C07D207/337 ,  C07D207/34 ,  C07D405/06 ,  C07F9/54 ,  C07F9/65

Abstract: 7-[1H-Pyrrol-3-yl]-substituted 3,5-dihydroxyhept-6-enoic acids and 7-[1H-pyrrol-3-yl]-substituted 3,5-dihydroxyheptanoic acids of the formula I … … in which A, B, R , R , R , R and R have the meanings given, and the corresponding delta -lactones of the formula II … … are described.

公开(公告)号：FI890050A0

公开(公告)日：1989-01-05

申请号：FI890050

申请日：1989-01-05

Applicant: HOECHST AG

Inventor： BAADER EKKEHARD ,  KEREKJARTO BELA ,  JENDRALLA HEINER ,  BECK GERHARD

IPC: A61K20060101 ,  A61K31/50 ,  A61P3/06 ,  A61P9/10 ,  C07C43/23 ,  C07C45/30 ,  C07C45/63 ,  C07C49/04 ,  C07C49/16 ,  C07C49/223 ,  C07C49/567 ,  C07C49/76 ,  C07C49/782 ,  C07C49/80 ,  C07C49/813 ,  C07C49/84 ,  C07D20060101 ,  C07D237/08 ,  C07D237/24 ,  C07D405/06 ,  C07D

Abstract: 3,5-Dihydroxycarboxylic acids and their derivatives of the formula I and the corresponding lactones of the formula II in which R , R , R , R and X-Y have the meanings given, process for the preparation of these compounds, their use as medicines and pharmaceutical compositions are described. Novel intermediates for the preparation of the compounds of the formulae I and II are additionally described.