公开(公告)号：KR810000853B1

公开(公告)日：1981-08-10

申请号：KR770000453

申请日：1977-02-25

Applicant: HOECHST AG

Inventor： URBANIETZ J ,  LOEWE H ,  KIRSCH R ,  DUWEL D

IPC: C07C128/00

Abstract: Title compds. (I; R,R1 = -COR4, -C=N-COOR5(NHCOR6); R4 = H, alkyl, cycloalkyl, amino and alkoxy; R5 = alkyl, alkenyl, alkinyl; R6 = H, alkyl, cycloalkyl, alkenyloxy, aralkyl and alkenyl; R2, R3 = H, C1-4 alkoxy, halogen, trifluoromethyl, and C1-4 alkyl; X = -O-SO2, -SO2-O; R7 = C1-4 alkyl), useful as parasiticides, were manufd. by reaction of II and III. Thus, 2-amino-4-phenoxysulfonyl-acetanilide refluxed with N,N'-bis-methoxy-carbonylisothio-urea-S-methylether and mixed with ethylacetate to give N-(2-acetamino-5-phenoxy-sulfonylphenyl)-N',N"-bis-methoxycarbony1-guanidine.

公开(公告)号：KR810001277B1

公开(公告)日：1981-10-10

申请号：KR810000396

申请日：1981-02-09

Applicant: HOECHST AG

Inventor： KIRSCH R ,  LOEWE H ,  URBANIETZ J ,  DUWEL D

IPC: C07C155/02

公开(公告)号：US3784633A

公开(公告)日：1974-01-08

申请号：US3784633D

申请日：1972-05-16

Applicant: HOECHST AG

Inventor： SCHORR M ,  DUWEL D

IPC: C07D233/26 ,  C07D49/34

CPC classification number: C07D233/26

Abstract: -2-IMIDAZOLINE

IN WHICH X AND Y STANDS FOR HYDROGEN OR HALOGEN.

IMIDAZOLINYL-ETHYL-DITHIOCARBAMIC ACID ESTERS AND THEIR PHYSIOLOGICALLY COMPATIBLE SALTS ARE DESCRIBED AS WELL AS THE PROCESS OF THEIR MANUFACTURE AND THEIR ANTHELMINTIC ACTION. THE NOVEL COMPOUNDS CORRESPOND TO FORMULA I

2-(4-(NC-)PHENYL),1-((X,Y-PHENYL)-CH2-S-C(=S)-NH-CH2-CH2-)

公开(公告)号：US3812131A

公开(公告)日：1974-05-21

申请号：US24498172

申请日：1972-04-17

Applicant: HOECHST AG

Inventor： SCHORR M ,  DURCKHEIMER W ,  BEHRENDT L ,  DUWEL D

IPC: C07D215/48 ,  C07D217/12 ,  C07D33/60 ,  C07D35/44

CPC classification number: C07D217/12 ,  C07D215/48

Abstract: ANTHELMINITICALLY ACTIVE PHENYLENE-BIS-DITHIOCARBAMIC ACID ESTERS OF THE FORMULA

BIS(R3-CH2-S-C(=S)-NH-),R1,R2-BENZENE

IN WHICH R1 AND R2 ARE EQUAL OR DIFFERENT AND REPRESENT HYDROGEN, HALOGEN, ALKYL OR ALKOXYL HAVING FROM 1 TO 6 CARBON ATOMS AND R3 IS PYRIDYL, QUINOLYL OR ISOQUINOLYL WHICH MAY BE SUBSTITUTED BY ONE OR MORE ALKYL RADICALS HAVING FROM 1 TO 6 CARBON ATOMS. A PROCESS FOR THEIR PREPARATION.

公开(公告)号：US3792054A

公开(公告)日：1974-02-12

申请号：US3792054D

申请日：1972-05-31

Applicant: HOECHST AG

Inventor： RUSHIG H ,  DUWEL D ,  KONIG J

IPC: A61K31/165 ,  A23K1/16 ,  A61K31/22 ,  A61K31/245 ,  A61P33/00 ,  C07C67/00 ,  C07C231/00 ,  C07C231/12 ,  C07C235/56 ,  C07C235/64 ,  C07D307/68 ,  F23Q7/02 ,  F24C5/14 ,  C07D29/30

CPC classification number: A61K31/245 ,  C07D307/68 ,  Y10S514/893

Abstract: DIACYLOXY-BENZOIC ACID ANILIDES OF THE GENERAL FORMULA

1-((R1-PHENYL)-NH-CO-),2,6-DI(R2-COO-),3-X,5-(O2N-)BENZENE

IN WHICH X REPRESENTS HYDROGEN OR HALOGEN, R1 REPRESENTS 1 TO 3 NITRO GROUPS, TRIFLUOROMETHYL GROUPS AND/OR HYDROGEN; LOWER ALKYL WHICH MAY BE SUBR2 REPRESENTS HYDROGEN; LOWER ALKYL WHICH MAE SUBSTITUTED BY HALOGEN, LOWER ALKOXY OR PHENYL; ALKENYL HAVING 3 TO 6 CARBON ATOMS; CYCLOALKYL HAVING 4 TO 6 CARBON ATOMS; PHENYL; AN UNSATURATED HETEROCYCLIC 5OR 6-MEMBERED RING; ALKYL-AMINO OR DIALKYL-AMINO IN WHICH THE ALKYL GROUPS EACH CONTAIN 1 TO 4 CARBON ATOMS OR MAY FORM TOGETHER WITH THE NITROGEN ATOM A PYRROLIDINE, PIPERIDINE, MORPHOLINE OR N-METHYL-PIPERAZINE RING.

公开(公告)号：US3746765A

公开(公告)日：1973-07-17

申请号：US3746765D

申请日：1971-08-05

Applicant: HOECHST AG

Inventor： RUSCHIG H ,  KOENIG J ,  DUWEL D ,  DITTMAR W ,  KLATT P

IPC: C07C235/84 ,  A61K20060101 ,  A61K31/00 ,  A61K31/16 ,  A61K31/165 ,  A61K31/18 ,  C07C20060101 ,  C07C233/00 ,  C07C233/12 ,  C07C327/38 ,  C07C103/86 ,  C07C153/05

CPC classification number: C07C265/12

Abstract: A COMPOUND OF FORMULA I

(2,6-DI(O=)CYCLOHEXYL)-C(=X)-NH-C6H3(-R1)-R2

IN WHICH X REPRESENTS ORYGEN OR SULFUR, R1 REPRESENTS HALOGEN, TRIFLUOROMETHYL, NITRO, ALKYL OF 1 TO 4 CARBON ATOMS, ALKOXY OF 1 TO 4 CARBON ATOMS OR HALOGEN-ALKOXY OF 1 TO 4 CARBON ATOMS, OR, IF X STANDS FOR SULFUR, R1 STANDS FOR HYDROGEN, AND R2 REPRESENTS HYDROGEN OR THE SUBSTITUENTS GIVEN FOR R1, WICH COMPOUND HAS INTERESTING CHEMOTHERAPEUTICAL PROPERTIES AND IS EFFECTIVE AGAINST INTESTINAL WORMS AS HELMINTHS, ESPECIALLY AGAINST LIVER FLUKES. BECAUSE OF THEIR ANTIMYCOTIC PROPERTIES, THE COMPOUNDS OF THE INVENTION MAY ALSO BE USED IN HUMAN MEDICINE AND IN VETERINARY MEDICINE TO ATTACK FUNGUS INFECTIONS.

公开(公告)号：JPS4820540B1

公开(公告)日：1973-06-21

申请号：JP4839070

申请日：1970-06-04

Applicant: HOECHST AG

Inventor： RUSCHIG H ,  DUWEL D ,  KONIG J

IPC: A61K31/165 ,  A23K1/16 ,  A61K31/22 ,  A61K31/245 ,  A61P33/00 ,  C07C67/00 ,  C07C231/00 ,  C07C231/12 ,  C07C235/56 ,  C07C235/64 ,  C07D307/68 ,  F23Q7/02 ,  F24C5/14 ,  C07C103/74

公开(公告)号：SE7702204L

公开(公告)日：1977-08-29

申请号：SE7702204

申请日：1977-02-28

Applicant: HOECHST AG

Inventor： LOEWE H ,  URBANIETZ J ,  DUWEL D ,  KIRSCH R

IPC: A61K31/165 ,  A61P33/10 ,  C07C67/00 ,  C07C301/00 ,  C07C303/30 ,  C07C309/72 ,  C07C309/76 ,  C08B5/10

公开(公告)号：EG11122A

公开(公告)日：1977-05-31

申请号：EG54172

申请日：1972-12-26

Applicant: HOECHST AG

Inventor： LOEWE H ,  DUWEL D ,  URBANIETZ J ,  DUWEL R

IPC: C07D235/30 ,  A23K1/16 ,  C07D235/32 ,  A61K31/41 ,  C07D235/04

Abstract: 2-Carbalkoxy-amino-benzimidazole-5(6)-phenyl ethers of the formula (I) in which R1 represents alkyl of 1 to 4 carbon atoms, R2 and R3 represent, independently of each other, hydrogen, hydroxyl, alkoxy of 1 to 4 carbon atoms, halogen, trifluoromethyl, alkyl of 1 to 4 carbon atoms or carbalkoxy of 1 to 4 carbon atoms in the alkoxy group, R4 represents hydrogen or chlorine and X represents oxygen or sulfur, useful as anthelmintics.

公开(公告)号：SE7610311A

公开(公告)日：1977-03-20

申请号：SE7610311

申请日：1976-09-16

Applicant: HOECHST AG

Inventor： LOEWE H ,  URBANIETZ J ,  DUWEL D ,  KIRSCH R

IPC: C07D235/32 ,  C07D285/16

CPC classification number: C07D285/16 ,  C07D235/32