公开(公告)号：HUT65847A

公开(公告)日：1994-07-28

申请号：HU9303170

申请日：1993-11-09

Applicant: HOECHST AG

Inventor： KORB GERHARD ,  FLEMMING HANS-WOLFRAM

IPC: A61K31/52 ,  C07D473/06 ,  C07D473/10

公开(公告)号：CZ238293A3

公开(公告)日：1994-05-18

申请号：CZ238293

申请日：1993-11-08

Applicant: HOECHST AG

Inventor： KORB GERHARD ,  FLEMMING HANS-WOLFRAM

IPC: A61K31/52 ,  C07D473/06 ,  C07D473/10

公开(公告)号：FI934928A0

公开(公告)日：1993-11-08

申请号：FI934928

申请日：1993-11-08

Applicant: HOECHST AG

Inventor： KORB GERHARD ,  FLEMMING HANS-WOLFRAM

IPC: A61K31/52 ,  C07D473/06 ,  C07D473/10 ,  C07D

公开(公告)号：DK69589A

公开(公告)日：1989-08-17

申请号：DK69589

申请日：1989-02-15

Applicant: HOECHST AG

Inventor： RIPPEL ROBERT ,  FLEMMING HANS-WOLFRAM ,  RUKWIED MANFRED

IPC: C07D333/36 ,  C07D333/38 ,  C07D333/48

Abstract: Thiophene derivatives with an optionally substituted amino group on the thiophene ring are prepared by dehydrogenation of dihydrothiophenes which are substituted in the same manner as the desired thiophene derivatives, using H2O2, the dihydrothiophenes being reacted in a first reaction step with H2O2 in neutral medium to give the corresponding sulphoxides, and, in the second reaction step, these are then rearranged with acid to give the thiophene derivatives. The dihydrothiophene-1-oxides which are formed in this process as intermediates are novel compounds. They, and equally the thiophene derivatives obtained from them by rearrangement with acid, are intermediates mainly in the crop protection agent sector and pharmaceutical sector.

公开(公告)号：RO112617B1

公开(公告)日：1997-11-28

申请号：RO9301494

申请日：1993-11-08

Applicant: HOECHST AG

Inventor： KORB GERHARD ,  FLEMMING HANS-WOLFRAM

IPC: A61K31/52 ,  C07D473/06 ,  C07D473/10

公开(公告)号：IE67293B1

公开(公告)日：1996-03-20

申请号：IE371789

申请日：1989-11-21

Applicant: HOECHST AG

Inventor： FLEMMING HANS-WOLFRAM ,  RUKWIED MANFRED ,  SCHMIDT MANFRED

IPC: C12P21/02 ,  C07K1/08 ,  C07K1/113 ,  C07K5/08 ,  C07K5/097

公开(公告)号：CZ9302382A3

公开(公告)日：1994-05-18

申请号：CZ238293

申请日：1993-11-08

Applicant: HOECHST AG

Inventor： KORB GERHARD ,  FLEMMING HANS-WOLFRAM

IPC: A61K31/52 ,  C07D473/06 ,  C07D473/10

CPC classification number: C07D473/06 ,  C07D473/10

公开(公告)号：PT89717B

公开(公告)日：1994-03-31

申请号：PT8971789

申请日：1989-02-15

Applicant: HOECHST AG

Inventor： RIPPEL ROBERT ,  FLEMMING HANS-WOLFRAM ,  RUKWIED MANFRED

IPC: C07D333/36 ,  C07D333/38 ,  C07D333/48 ,  C07D333/68

Abstract: Thiophene derivatives with an optionally substituted amino group on the thiophene ring are prepared by dehydrogenation of dihydrothiophenes which are substituted in the same manner as the desired thiophene derivatives, using H2O2, the dihydrothiophenes being reacted in a first reaction step with H2O2 in neutral medium to give the corresponding sulphoxides, and, in the second reaction step, these are then rearranged with acid to give the thiophene derivatives. The dihydrothiophene-1-oxides which are formed in this process as intermediates are novel compounds. They, and equally the thiophene derivatives obtained from them by rearrangement with acid, are intermediates mainly in the crop protection agent sector and pharmaceutical sector.

公开(公告)号：IN170286B

公开(公告)日：1992-03-07

申请号：IN913MA1989

申请日：1989-12-11

Applicant: HOECHST AG

Inventor： KORB GERHARD ,  FLEMMING HANS-WOLFRAM

IPC: C07D277/20 ,  B01J31/02 ,  C07B61/00 ,  C07C59/185 ,  C07C59/21 ,  C07C333/16 ,  C07D277/36

公开(公告)号：DK584489A

公开(公告)日：1990-05-23

申请号：DK584489

申请日：1989-11-21

Applicant: HOECHST AG

Inventor： FLEMMING HANS-WOLFRAM ,  RUKWIED MANFRED ,  SCHMIDT MANFRED

IPC: C12P21/02 ,  C07K1/08 ,  C07K1/113 ,  C07K5/08 ,  C07K5/097 ,  C07K1/06