Pyran-carboxylic acid anilides
    1.
    发明授权
    Pyran-carboxylic acid anilides 失效
    吡咯烷酸酰胺

    公开(公告)号:US3632821A

    公开(公告)日:1972-01-04

    申请号:US3632821D

    申请日:1969-01-14

    Applicant: HOECHST AG

    Abstract: IN WHICH R STANDS FOR HYDROGEN, METHYL OR METHOXY IN THE META, ORTHO OR PAR-POSITION IN THE BENZENE NUCLEUS. THE NOVEL COMPOUNDS ARE USED AS FUNGICIDES.

    2-(CH3-),3-((R-PHENYL)-NH-CO-)-5,6-DIHYDROPYRAN

    2-METHYL-5,6-DIHYDROPYRAN-3-CARBOXYLIC ACID ANILIDES OF THE GENERAL FORMULA

    ISOXAZOLE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND COMPOSITIONS CONTAINING THESE COMPOUNDS

    公开(公告)号:CA1076584A

    公开(公告)日:1980-04-29

    申请号:CA254134

    申请日:1976-06-04

    Applicant: HOECHST AG

    Inventor: HEUBACH GUNTHER

    Abstract: A 5-methyl-isoxazole-4-carboxylic acid anilide of the general formula (I) in which preferably R1 and R2 stand for hydrogen, R3 for halogen atoms, the CF3 group or an alkoxy group of 1 or 2 carbon atoms which may be substituted in part or entirely by halogen atoms; or R1 stands for hydrogen, R2 and R3 for halogen atoms or the CF3 group; or R1 stands for hydrogen, R2 for an alkyl group of 1 or 2 carbon atoms and R3 for a halogen, is prepared by heating an acetoacetic acid anilide with an orthoformic acid ester and a carboxylic acid anhydride, isolating the resulting 2-alkoxy-methylene-acetoacetic acid anilide and then treating it with hydroxylamine in an organic solvent. The compounds of the invention have anti-inflammatory and analgetic activity.

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