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公开(公告)号：KR860002184B1
公开(公告)日：1986-12-24
申请号：KR780000888
申请日：1978-03-30
Applicant: HOECHST AG
Inventor： DURCKHEIMER WALTER , BORMANN DIETER , EBLERS EBERHARD , SCHRINNER ELMAR , HEYMES RENE
IPC: C07D501/24 , C07D501/36 , C07D501/46
Abstract: Title compds. I[R1=H, protected amino; R2=H, alkyl, alkenyl, Ph, benzyl; R3=H, ester, anion; R4=H, alkoxy; A=-CH2SR5, -CH2Y; R5=hetero cyclic group; Y=pyridinium, quinolinium group! were prepd. Thus, 2.6 g mixt. of H2O, ethanol, and 7-beta-[alpha-sinmethoximino-alpha-(2- amino-thiazol-4-yl)-acetamido!-cephalosporanic acid were dissolved in 50ml H2O with 1.5 g 2-mercapto-3-oxy-4phenyl-1,3-thiazole and incubated for 2 h at 64≦̸C at pH 6.0-7.0 to give 0.9 g 7-beta-[alpha- sin-methoximino-alpha-(2-amino-thiazol-4yl)-acetamido!-3-(3-oxy-4- phenyl-1,3-thiazol-2-yl-thiomethyl)-3cephem-4-carboxylic acid.
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公开(公告)号：AU558695B2
公开(公告)日：1987-02-05
申请号：AU1567583
申请日：1983-06-09
Applicant: HOECHST AG
Inventor： DURCKHEIMER WALTER , BORMANN DIETER , EHLERS EBERHARD , SCHRINNER ELMER , HEYMES RENE
IPC: C07D463/00 , C07D501/20 , C07D501/36 , C07D501/57 , C07D505/00 , C07D519/00 , C07F9/32
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公开(公告)号：FI852252L
公开(公告)日：1985-06-05
申请号：FI852252
申请日：1985-06-05
Applicant: HOECHST AG
Inventor： DUERCKHEIMER WALTER , BORMANN DIETER , EHLERS EBERHARD , SCHRINNER ELMAR , HEYMES RENE
IPC: C07D20060101 , C07D
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公开(公告)号：FI852252A0
公开(公告)日：1985-06-05
申请号：FI852252
申请日：1985-06-05
Applicant: HOECHST AG
Inventor： DUERCKHEIMER WALTER , BORMANN DIETER , EHLERS EBERHARD , SCHRINNER ELMAR , HEYMES RENE
IPC: C07D20060101 , C07D
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公开(公告)号：CS208747B2
公开(公告)日：1981-09-15
申请号：CS214478
申请日：1978-04-03
Applicant: HOECHST AG
Inventor： DUERCKHEIMER WALTER , BORMANN DIETER , EHLERS EBERHARD , SCHRINNER ELMAR , HEYMES RENE
IPC: A61K31/397 , A61K31/435 , A61K31/505 , A61K31/535 , A61K31/545 , A61K31/546 , A61P31/04 , B25J15/08 , C07D205/08 , C07D277/20 , C07D277/40 , C07D277/42 , C07D277/50 , C07D463/00 , C07D471/04 , C07D487/04 , C07D498/04 , C07D501/20 , C07D501/24 , C07D501/36 , C07D505/00 , C07D519/06 , C07F9/6561 , C07D501/60
Abstract: Cephem derivatives of the general formula in which the R2O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.
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Patent Agency Ranking
公开(公告)号：AU3464878A
公开(公告)日：1979-10-04
申请号：AU3464878
申请日：1978-03-31
Applicant: HOECHST AG
Inventor： DURCKHEIMER WALTER , BORMANN DIETER , EHLERS EBERHARD , SCHRINNER ELMER , HEYMES RENE
IPC: A61K31/397 , A61K31/435 , A61K31/505 , A61K31/535 , A61K31/545 , A61K31/546 , A61P31/04 , B25J15/08 , C07D205/08 , C07D277/20 , C07D277/40 , C07D277/42 , C07D277/50 , C07D463/00 , C07D471/04 , C07D487/04 , C07D498/04 , C07D501/20 , C07D501/24 , C07D501/36 , C07D505/00 , C07D519/06 , C07F9/6561 , C07D501/22 , C07D501/34 , C07D501/46 , A61K31/44
Abstract: Cephem derivatives of the general formula in which the R2O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.
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公开(公告)号：NO781130L
公开(公告)日：1978-10-03
申请号：NO781130
申请日：1978-03-31
Applicant: HOECHST AG
Inventor： DUERCKHEIMER WALTER , BORMANN DIETER , EHLERS EBERHARD , SCHRINNER ELMAR , HEYMES RENE
IPC: A61K31/397 , A61K31/435 , A61K31/505 , A61K31/535 , A61K31/545 , A61K31/546 , A61P31/04 , B25J15/08 , C07D205/08 , C07D277/20 , C07D277/40 , C07D277/42 , C07D277/50 , C07D463/00 , C07D471/04 , C07D487/04 , C07D498/04 , C07D501/20 , C07D501/24 , C07D501/36 , C07D505/00 , C07D519/06 , C07F9/6561 , C07D
Abstract: Cephem derivatives of the general formula in which the R2O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.
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公开(公告)号：NO781130A
公开(公告)日：1978-10-03
申请号：NO781130
申请日：1978-03-31
Applicant: HOECHST AG
Inventor： DUERCKHEIMER WALTER , BORMANN DIETER , EHLERS EBERHARD , SCHRINNER ELMAR , HEYMES RENE
IPC: A61K31/397 , A61K31/435 , A61K31/505 , A61K31/535 , A61K31/545 , A61K31/546 , A61P31/04 , B25J15/08 , C07D205/08 , C07D277/20 , C07D277/40 , C07D277/42 , C07D277/50 , C07D463/00 , C07D471/04 , C07D487/04 , C07D498/04 , C07D501/20 , C07D501/24 , C07D501/36 , C07D505/00 , C07D519/06 , C07F9/6561 , C07D
CPC classification number: C07D277/20 , A61K31/435 , A61K31/505 , A61K31/535 , A61K31/545 , C07D277/40 , C07D277/42 , C07D277/50 , C07D277/587 , C07D463/22 , C07D471/04 , C07D487/04 , C07D498/04 , C07D505/00
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公开(公告)号：DK165060C
公开(公告)日：1993-02-22
申请号：DK143378
申请日：1978-03-31
Applicant: HOECHST AG
Inventor： DUERCKHEIMER WALTER , BORMANN DIETER , EHLERS EBERHARD , SCHRINNER ELMAR , HEYMES RENE
IPC: A61K31/397 , A61K31/435 , A61K31/505 , A61K31/535 , A61K31/545 , A61K31/546 , A61P31/04 , B25J15/08 , C07D205/08 , C07D277/20 , C07D277/40 , C07D277/42 , C07D277/50 , C07D463/00 , C07D471/04 , C07D487/04 , C07D498/04 , C07D501/20 , C07D501/24 , C07D501/36 , C07D505/00 , C07D519/06 , C07F9/6561
Abstract: Cephem derivatives of the general formula in which the R2O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.
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公开(公告)号：NO160211C
公开(公告)日：1989-03-22
申请号：NO781130
申请日：1978-03-31
Applicant: HOECHST AG
Inventor： DUERCKHEIMER WALTER , BORMANN DIETER , EHLERS EBERHARD , SCHRINNER ELMAR , HEYMES RENE
IPC: A61K31/397 , A61K31/435 , A61K31/505 , A61K31/535 , A61K31/545 , A61K31/546 , A61P31/04 , B25J15/08 , C07D205/08 , C07D277/20 , C07D277/40 , C07D277/42 , C07D277/50 , C07D463/00 , C07D471/04 , C07D487/04 , C07D498/04 , C07D501/20 , C07D501/24 , C07D501/36 , C07D505/00 , C07D519/06 , C07F9/6561
Abstract: Cephem derivatives of the general formula in which the R2O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.
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