公开(公告)号：CH368136A

公开(公告)日：1963-05-15

申请号：CH260061

申请日：1961-03-03

Applicant: HOECHST AG

Inventor： HEYNA JOHANNES ,  GRUNEWALD HANS-JOACHIM ,  SCHMIDT HELMUT ,  WECKLER GERHARD

IPC: D06P1/44

公开(公告)号：CA594539A

公开(公告)日：1960-03-15

申请号：CA594539D

Applicant: HOECHST AG

Inventor： HEYNA JOHANNES ,  BESTIAN HERBERT ,  RUCKERT ALFRED ,  WENGHOFER JOHANN

公开(公告)号：CA605901A

公开(公告)日：1960-09-27

申请号：CA605901D

Applicant: HOECHST AG

Inventor： NOLL WALTER ,  HEYNA JOHANNES ,  SCHUMACHER WILHELM

公开(公告)号：CA544249A

公开(公告)日：1957-07-30

申请号：CA544249D

Applicant: HOECHST AG

Inventor： HEYNA JOHANNES ,  SCHUMACHER WILHELM

公开(公告)号：CA716099A

公开(公告)日：1965-08-17

申请号：CA716099D

Applicant: HOECHST AG

Inventor： SCHINZEL ERICH ,  HEYNA JOHANNES ,  BERLIN LUDWIG W

公开(公告)号：CA657500A

公开(公告)日：1963-02-12

申请号：CA657500D

Applicant: HOECHST AG

Inventor： RUCKERT ALFRED ,  BARTL HUGO ,  HEYNA JOHANNES ,  DIERY HELMUT ,  BESTIAN HERBERT

公开(公告)号：GB854443A

公开(公告)日：1960-11-16

申请号：GB1794657

申请日：1957-06-05

Applicant: HOECHST AG

Inventor： DIERY HELMUT ,  SCHMIDT-RUPPIN HEINZ ,  HEYNA JOHANNES

IPC: B28C9/00 ,  C07F9/564

Abstract: The invention comprises ethyleneimine derivatives of the formula : in which R is an alkyl, cycloalkyl or aryl group. They may be obtained by reacting an appropriate thiophosphoric monoester dihalide, e.g. chloride or bromide with ethyleneimine in the presence of an acid-binding agent. Specified acid binding agents are tertiary amines, e.g. trimethylamine or triethylamine, anhydrous ammonia, sodium carbonate, potassium carbonate, sodium acetate, and sodium hydroxide. The reaction may be carried out in an aqueous medium or in an organic solvent, e.g. a hydrocarbon, chlorinated hydrocarbon, ketone or ether. Examples are given for the production of products of the above formula in which R is ethyl, butyl, cyclohexyl, isobutyl, n-amyl, and phenyl respectively. The products have the property of checking the growth of malignant tumours.

公开(公告)号：CA826723A

公开(公告)日：1969-11-04

申请号：CA826723D

Applicant: HOECHST AG

Inventor： SCHMIDT HELMUT ,  WECKLER GERHARD ,  HEYNA JOHANNES ,  GRUNEWALD HANNS-JOACHIM

公开(公告)号：CA623328A

公开(公告)日：1961-07-04

申请号：CA623328D

Applicant: HOECHST AG

Inventor： HEYNA JOHANNES ,  NOLL WALTER

公开(公告)号：CA610010A

公开(公告)日：1960-12-06

申请号：CA610010D

Applicant: HOECHST AG

Inventor： DIERY HELMUT ,  HEYNA JOHANNES ,  SCHMIDT-RUPPIN HEINZ