公开(公告)号：CA1310019C

公开(公告)日：1992-11-10

申请号：CA590714

申请日：1989-02-10

Applicant: HOECHST AG

Inventor： HEISE HARTMUT ,  HINTZMANN MANFRED

IPC: B01J23/755 ,  C07B61/00 ,  C07C231/02 ,  C07C233/25 ,  C07C233/43

Abstract: HOE 88/F 029 A process for the preparation of 4-acylamino-2-amino-alkoxybenzenes of the general formula (1) (1) in which R denotes an alkyl-C1-C6- or alkoxy-C1-C4-alkylene-C1-C4 group and R' denotes a methyl or ethyl group, by pumping a solution or suspension of a 2,4-di-nitroalkoxybenzene of the general formula (2) (2) in which R has the abovementioned meaning, in a butyl acetate into a stirred suspension of a nickel catalyst on a kieselguhr carrier in butyl acetate, which has been initially introduced into an autoclave, at a hydrogen pressure of about 5 to about 50 bar, and a temperature of about 60 to about 120.degree.C, at a rate which corresponds to the rate of hydrogenation of 2,4-dinitroalkoxybenzene to 2,4-diaminoalkoxybenzene, dehydrating the reduction solution by azeotropic distillation, after the hydrogenation, and acylating the resulting 2,4-diaminoalkoxybenzene with about 0.90 to 0.99 mole of the anhydride of an alkylmonocarboxylic acid having 2 to 3 carbon atoms, relative to 1 mole of 2,4-diaminoalkoxybenzene, at about -5 to about +15.degree.C

公开(公告)号：BR8900600A

公开(公告)日：1989-10-10

申请号：BR8900600

申请日：1989-02-10

Applicant: HOECHST AG

Inventor： HEISE HARTMUT ,  HINTZMANN MANFRED

IPC: B01J23/755 ,  C07B61/00 ,  C07C231/02 ,  C07C233/25 ,  C07C233/43 ,  C07C103/44

Abstract: Process for the preparation of 4-acylamino-2-aminoalkoxybenzenes of the formula (1) … … in which R denotes a C1-C6-alkyl or C1-C4-alkoxy-C1-C4-alkylene group and R' denotes a methyl or ethyl group, by pumping a solution or suspension of a 2,4-dinitroalkoxybenzene of the formula (2) … … in which R has the said meaning, in a butyl acetate into a suspension of a nickel catalyst on a kieselguhr support in butyl acetate, which is initially introduced into an autoclave and stirred, at a hydrogen pressure of about 5 to 50 bar and a temperature of about 60 to about 120 DEG C at a rate which corresponds to the rate of hydrogenation of the 2,4-dinitroalkoxybenzene to the 2,4-diaminoalkoxybenzene, removing water from the reduction solution by azeotropic distillation after the hydrogenation and acylating the resultant 2,4-diaminoalkoxybenzene with about 0.90 to about 0.99 mol of the anhydride of an alkyl- monocarboxylic acid of 2 to 3 C atoms, relative to 1 mol of 2,4-diaminoalkoxybenzene, at about -5 to about +15 DEG C.

公开(公告)号：MX170939B

公开(公告)日：1993-09-22

申请号：MX1491789

申请日：1989-02-13

Applicant: HOECHST AG

Inventor： HEISE HARTMUT ,  HINTZMANN MANFRED

IPC: B01J23/755 ,  C07B61/00 ,  C07C231/02 ,  C07C233/25 ,  C07C233/43 ,  C07C103/44

Abstract: Process for the preparation of 4-acylamino-2-aminoalkoxybenzenes of the formula (1) … … in which R denotes a C1-C6-alkyl or C1-C4-alkoxy-C1-C4-alkylene group and R' denotes a methyl or ethyl group, by pumping a solution or suspension of a 2,4-dinitroalkoxybenzene of the formula (2) … … in which R has the said meaning, in a butyl acetate into a suspension of a nickel catalyst on a kieselguhr support in butyl acetate, which is initially introduced into an autoclave and stirred, at a hydrogen pressure of about 5 to 50 bar and a temperature of about 60 to about 120 DEG C at a rate which corresponds to the rate of hydrogenation of the 2,4-dinitroalkoxybenzene to the 2,4-diaminoalkoxybenzene, removing water from the reduction solution by azeotropic distillation after the hydrogenation and acylating the resultant 2,4-diaminoalkoxybenzene with about 0.90 to about 0.99 mol of the anhydride of an alkyl- monocarboxylic acid of 2 to 3 C atoms, relative to 1 mol of 2,4-diaminoalkoxybenzene, at about -5 to about +15 DEG C.

公开(公告)号：CA1303064C

公开(公告)日：1992-06-09

申请号：CA568040

申请日：1988-05-27

Applicant: HOECHST AG

Inventor： HECK DIETER ,  HEISE HARTMUT ,  HINTZMANN MANFRED

IPC: C07C205/38 ,  C07C67/00 ,  C07C201/00 ,  C07C201/12 ,  C07C205/31 ,  C07C205/37

Abstract: HOE 87/F 175 J of the disclosure A process for the preparation of 2,4-dinitrophenyl ethers of the general formula (1) (1) in which R denotes an alkyl(C1-C6) or alkoxy(C1-C4)-alkyl(C1-C4) group by reacting 1 mole of 2,4-dinitro-chlorobenzene in the anhydrous alcohol which is required for the ether formation and is of the general formula (2) R - OH (2) in which R has the abovementioned meaning, in the presence of 1.0 to 3.0 mole of an anhydrous alkali metal carbonate, at temperatures of 20.degree.C to 150.degree.C, where appropriate under pressure.