公开(公告)号：ZA8401138B

公开(公告)日：1984-09-26

申请号：ZA8401138

申请日：1984-02-16

Applicant: HOECHST AG

Inventor： BALBIR SINGH BAJWA ,  DIPAK KUMAR CHATTERJEE ,  REDEN JUERGEN ,  BIMAL NARESH GANGULI ,  SOUZA NOEL JOHN DE

IPC: C07D221/14 ,  C07D221/12 ,  C07D401/04 ,  C07D401/14 ,  C07D493/06 ,  C07D ,  A61K

CPC classification number: C07D401/14 ,  C07D221/12 ,  C07D493/06

公开(公告)号：CA1106358A

公开(公告)日：1981-08-04

申请号：CA318498

申请日：1978-12-22

Applicant: HOECHST AG

Inventor： BLUMBACH JUERGEN ,  DUERCKHEIMER WALTER ,  REDEN JUERGEN ,  SELIGER HUBERT

IPC: C07D417/12 ,  C07D499/00 ,  C07D499/12 ,  C07D499/44 ,  C07D501/06 ,  C07D501/20

Abstract: Process for acylating 6-amino-penam and 7-amino-cephem derivatives by activating the acylating component with an optionally substituted 1-hydroxybenzotriazole and then reacting the activated derivative with the 6-amino-penam or 7-amino-cepham derivative.

公开(公告)号：ZA841138B

公开(公告)日：1984-09-26

申请号：ZA841138

申请日：1984-02-16

Applicant: HOECHST AG

Inventor： BALBIR SINGH BAJWA ,  DIPAK KUMAR CHATTERJEE ,  REDEN JUERGEN ,  BIMAL NARESH GANGULI ,  SOUZA NOEL JOHN DE

IPC: C07D221/14 ,  A61K31/365 ,  A61K31/435 ,  A61K31/445 ,  C07D221/12 ,  C07D401/04 ,  C07D401/14 ,  C07D493/06 ,  C07D ,  A61K

Abstract: The present invention relates to new bisamidine derivatives of polycyclic compounds such as 5,10-dioxo-4,5,9,10-tetrahydro-4,9-dioxapyrene-6(5H)-phenanthridone and 5,10-dioxo-4,5,9,10-tetrahydro-4,9-dioxapyrenephenanthridine and to a process for their preparation. The polycyclic bisamidines according to the invention are distinguished by valuable chemotherapeutic properties, such as, for example, an action against amoebas and trichomonads.