公开(公告)号：AT13664T

公开(公告)日：1985-06-15

申请号：AT81107071

申请日：1981-09-09

Applicant: HOECHST AG

Inventor： STURM KARL DR

IPC: C07D307/52 ,  C07C143/80 ,  C07C139/00 ,  C07C147/12

公开(公告)号：CH470355A

公开(公告)日：1969-03-31

申请号：CH1364068

申请日：1968-07-08

Applicant: HOECHST AG

Inventor： STURM KARL DR ,  NAHM HELMUT DR ,  PROF SIEDEL WALTER DR

IPC: C07C209/22 ,  C07C311/37 ,  C07D307/52 ,  C07C143/80

公开(公告)号：CH638798A5

公开(公告)日：1983-10-14

申请号：CH446378

申请日：1978-04-25

Applicant: HOECHST AG

Inventor： STURM KARL DR ,  MUSCHAWECK ROMAN DR

IPC: A61K31/635 ,  A61P7/10 ,  C07D307/52 ,  C07D333/20 ,  A61K31/34 ,  A61K31/38

公开(公告)号：DE2412884A1

公开(公告)日：1975-10-16

申请号：DE2412884

申请日：1974-03-18

Applicant: HOECHST AG

Inventor： STURM KARL DR ,  STAREY FRANZ DR

IPC: C07D295/12 ,  C07D295/135 ,  C07D295/22 ,  C07D295/26 ,  C07D295/10

公开(公告)号：DE2339714A1

公开(公告)日：1975-02-27

申请号：DE2339714

申请日：1973-08-06

Applicant: HOECHST AG

Inventor： STURM KARL DR ,  MUSCHAWECK ROMAN DR ,  NAHM HELMUT DR

IPC: A61K31/18 ,  C07C143/80 ,  A61K31/19 ,  A61K31/34 ,  A61K31/44 ,  C07D213/63 ,  C07D307/42

Abstract: Cpds. (I):- (where R' is 1-6C alkyl opt. branched and opt. contng. one unsatd. bond; or an aralkyl group contng. up to 9C or 2-, 3- or 4- pyridylmethyl) may be prepd. either by reacting 3-butylamino-4-phenoxy-5-sulphamoyl benzoic acid (II) with R'OH and HCHO; or hydrogenating a (I)-benzyl ester, or reacting (I; R' = Me) with R'OH to give (I; R' = 2-6C alkyl). Thus (I; R' = Me) is prepd. by refluxing (II), HCHO and MeOH.

公开(公告)号：CH419152A

公开(公告)日：1966-08-31

申请号：CH98562

申请日：1962-01-26

Applicant: HOECHST AG

Inventor： PROF SIEDEL WALTER DR ,  STURM KARL DR ,  NAHM HELMUT DR

IPC: C07D285/28 ,  C07D285/30 ,  C07D93/34

公开(公告)号：AT12390T

公开(公告)日：1985-04-15

申请号：AT82100335

申请日：1982-01-19

Applicant: HOECHST AG

Inventor： STURM KARL DR ,  MUSCHAWECK ROMAN DR ,  HROPOT MAX DR

IPC: A61K31/63 ,  A61K31/635 ,  A61P7/10 ,  C07C67/00 ,  C07C301/00 ,  C07C303/40 ,  C07C311/39 ,  C07D307/52 ,  C07D333/20 ,  C07C143/80

公开(公告)号：DE3161905D1

公开(公告)日：1984-02-23

申请号：DE3161905

申请日：1981-02-10

Applicant: HOECHST AG

Inventor： STURM KARL DR ,  MUSCHAWECK ROMAN DR

IPC: A61K31/18 ,  A61K31/63 ,  A61P13/02 ,  A61P15/00 ,  C07C67/00 ,  C07C313/00 ,  C07C315/02 ,  C07C317/36 ,  C07D307/52 ,  C07D333/20 ,  C07C147/12

Abstract: What are disclosed are compounds of the formula I in which R denotes alkyl, alkenyl, cycloalkyl or cycloalkylalkyl, each of which has up to 10 C atoms, or phenyl and Ar denotes phenyl, thienyl or furyl and salts thereof, the preparation of these compounds and their use as medicaments and also medicaments of this type as such.

公开(公告)号：DE2507996A1

公开(公告)日：1976-08-26

申请号：DE2507996

申请日：1975-02-25

Applicant: HOECHST AG

Inventor： STURM KARL DR ,  STAREY FRANZ DR

IPC: C07D295/155 ,  C07D295/10 ,  C07D403/04

公开(公告)号：DE2334562A1

公开(公告)日：1975-01-30

申请号：DE2334562

申请日：1973-07-07

Applicant: HOECHST AG

Inventor： STURM KARL DR ,  STAREY FRANZ DR

IPC: A61K31/495 ,  C07D295/12

Abstract: Title cpds. are of formula (I) where R = alkyl, R' and R2 = H, Me or Et; R3 = H or alkyl, and R4 = H, alkyl, allyl opt. substd. by O, S, SO, SO2, or N-alkyl, where the N-atom may also form part of a satd. 5-6 membered heterocyclic ring, cycloalkyl, is not >8C cycloalkyl-alkyl, aralkyl opt. substd. by 1 or 2 hal, alkyl, alkoxy, NH alkyl, or N(alkyl)2, 2-furylmethyl, 2-tetrahydrofurylmethyl, or pyridylmethyl or NR3R4 is pyrolidino, piperidino, hexamethylenimino, morpholino or 4-alkylpiperazin-1-yl. (I) are prepd. by condensing the corresp. 2-, 4- or 2,4-di-halide or sulphonate, with the appropriate amine(s).