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    Test element for analyzing sample material
    2.
    发明专利
    Test element for analyzing sample material 审中-公开
    用于分析样品的试验元件

    公开(公告)号：JP2009036780A

    公开(公告)日：2009-02-19

    申请号：JP2008286235

    申请日：2008-11-07

    Applicant: F Hoffmann La Roche Ag ,  エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft

    Inventor： OCVIRK GREGOR ,  KALVERAM STEFAN ,  ROESICKE BERND

    IPC: G01N35/00 ,  B01L3/00 ,  C12Q1/54 ,  G01N33/48 ,  G01N33/66 ,  G01N33/86 ,  G01N35/08

    CPC classification number: C12Q1/54 ,  B01L3/5027 ,  B01L2300/0825 ,  B01L2300/0887 ,  B01L2300/1827 ,  B01L2400/0406 ,  G01N33/86

    Abstract: PROBLEM TO BE SOLVED: To improve a test element for analyzing sample materials, such as, blood and urine for ensuring reproducible measuring conditions, using economical manufacturing techniques and which are not complex. SOLUTION: The test element is equipped with a test carrier (12), including an analysis domain (18), to which sample materials are applicable and a heating element (22) contacting the analysis domain (18) through heat transfer and forms a heating element incorporated in the test carrier (12), by using a thermistor (22) performing self-heating and self-tuning so as to attain at a preset target temperature, when a current is made to flow. COPYRIGHT: (C)2009,JPO&INPIT

    Abstract translation: 要解决的问题：改进用于分析样品材料如血液和尿液的测试元件，以确保可重现的测量条件，使用经济的制造技术并且不复杂。 解决方案：测试元件配备有测试载体（12），包括分析域（18），样品材料可应用于其中，加热元件（22）通过热传递与分析域（18）接触， 通过使用进行自加热和自调谐的热敏电阻（22）形成加入到测试载体（12）中的加热元件，以便当电流流动时达到预设目标温度。 版权所有（C）2009，JPO＆INPIT

    Test element for analyzing sample material
    3.
    发明专利
    Test element for analyzing sample material 审中-公开
    用于分析样品的试验元件

    公开(公告)号：JP2005201893A

    公开(公告)日：2005-07-28

    申请号：JP2004361393

    申请日：2004-12-14

    Applicant: F Hoffmann La Roche Ag ,  エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft

    Inventor： OCVIRK GREGOR ,  KALVERAM STEFAN ,  ROESICKE BERND

    IPC: B01L3/00 ,  C12Q1/54 ,  G01N33/48 ,  G01N33/66 ,  G01N33/86 ,  G01N35/08

    CPC classification number: C12Q1/54 ,  B01L3/5027 ,  B01L2300/0825 ,  B01L2300/0887 ,  B01L2300/1827 ,  B01L2400/0406 ,  G01N33/86

    Abstract: PROBLEM TO BE SOLVED: To improve a test element for analyzing a sample material such as blood or urine, in such a manner that reproducible measuring conditions are ensured with economical manufacturing processes and uncomplicated apparatus.
    SOLUTION: The test element is equipped with a test carrier (12) which has an analytical area (18) to which the sample material can be applied, and a heating element (22) being in heat conducting contact with the analytical area (18), wherein the heat element integrated into the test carrier (12) is formed by a thermistor (22) which self-heats and self-regulates to a preset target temperature when current flows through it.
    COPYRIGHT: (C)2005,JPO&NCIPI

    Abstract translation: 要解决的问题：为了改善用于分析样品材料如血液或尿液的测试元件，以便以经济的制造工艺和不复杂的装置确保可再现的测量条件。

    解决方案：测试元件配备有具有可以施加样品材料的分析区域（18）的测试载体（12）和与分析区域热传导接触的加热元件（22） （18），其中集成到所述测试载体（12）中的所述热元件由热敏电阻（22）形成，所述热敏电阻在电流流过所述热敏电阻时自加热并自调节至预设目标温度。 版权所有（C）2005，JPO＆NCIPI

    Analysis inspection element performing data transmission by radio
    5.
    发明专利
    Analysis inspection element performing data transmission by radio 有权
    分析检测元件实现无线电数据传输

    公开(公告)号：JP2011085608A

    公开(公告)日：2011-04-28

    申请号：JP2011021769

    申请日：2011-02-03

    Applicant: F Hoffmann-La Roche Ag ,  エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト

    Inventor： ROESICKE BERND ,  SEIDENSTRICKER MANFRED

    IPC: G01N27/26 ,  G01N27/327 ,  G01N27/416

    CPC classification number: A61B5/6849 ,  A61B5/0002 ,  A61B5/14532 ,  A61B2560/0219 ,  A61B2560/0228 ,  A61B2562/0295 ,  G01N33/48792 ,  Y10T436/110833

    Abstract: PROBLEM TO BE SOLVED: To provide a system which includes an analysis inspection element and an apparatus separated therefrom, for determining the concentration of an analysis object material in a body fluid. SOLUTION: At least a part of an electrical component of the analysis inspection element is constituted of polymer electronic parts. The analysis inspection element has thereon a domain, including a detection chemical system for detecting an analysis object; and a transponder for transmitting by radio, data on a loading sample and/or a measurement value. The apparatus includes a reading module for transmitting by radio, data and energy to an inspection element, and an evaluation unit for evaluating the data or the measurement value received from the transponder. COPYRIGHT: (C)2011,JPO&INPIT

    Abstract translation: 要解决的问题：提供一种包括分析检查元件和与其分离的装置的系统，用于确定体液中的分析对象物质的浓度。 解决方案：分析检查元件的电气部件的至少一部分由聚合物电子部件构成。 分析检查元件具有包括检测分析对象的检测化学系统的域， 以及用于通过无线电发送关于加载样本的数据和/或测量值的应答器。 该装置包括用于通过无线电，数据和能量发送到检查元件的读取模块，以及用于评估从应答器接收的数据或测量值的评估单元。 版权所有（C）2011，JPO＆INPIT

    System for in-vivo measurement of analyte concentration
    6.
    发明专利
    System for in-vivo measurement of analyte concentration 审中-公开
    分析仪浓度测量系统

    公开(公告)号：JP2008246204A

    公开(公告)日：2008-10-16

    申请号：JP2008063259

    申请日：2008-03-12

    Applicant: F Hoffmann-La Roche Ag ,  エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト

    Inventor： ROESICKE BERND ,  OBERMAIER KARIN ,  LINDEGGER STEFAN ,  MENKE ANDREAS ,  SCHERER JOERG ,  SCHWIND KARIN ,  GAA OTTO ,  BAINCZYK GREGOR ,  MARQUANT MICHAEL ,  NIEDERHAEUSER SANDRO ,  SCHOEMAKER MICHAEL ,  MUERI MARTIN

    IPC: A61B5/145

    CPC classification number: A61B5/0031 ,  A61B5/0002 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1459 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/6849 ,  A61B5/7232 ,  A61B5/742 ,  A61B90/98 ,  A61B2560/0209 ,  A61B2560/0219 ,  A61B2560/0481

    Abstract: PROBLEM TO BE SOLVED: To improve reliability of a system for in-vivo measurement of analyte concentration.
    SOLUTION: The system for in-vivo measurement of analyte concentration in a human or animal body having at least an implantable sensor 3 for generating measuring signals that are correlated to the analyte concentration to be measured, a base station 2 that can be coupled to the sensor 3 and contains an electronic analytical unit 47 for analysis of the measuring signals of the sensor 3 connected to it, and a transmitter 31 for wireless transmission of analytical results, and a display 4 that has a receiver for receiving the analytical results transmitted by the base station 2 and a display 29 for displaying analyte concentration values. The invention provides the sensor 3 to be a part of a replaceable sensor housing unit 10 that has a closed housing 12 inside of which the sensor 3 is disposed, and provides the sensor housing unit 10 to fit to the base station 2 in order to couple the sensor 3 to the base station 2.
    COPYRIGHT: (C)2009,JPO&INPIT

    Abstract translation: 要解决的问题：提高用于体内测量分析物浓度的系统的可靠性。 解决方案：用于体内测量人体或动物体中分析物浓度的系统，其具有至少可植入传感器3，用于产生与要测量的分析物浓度相关的测量信号，基站2可以是 耦合到传感器3并且包含用于分析连接到其的传感器3的测量信号的电子分析单元47和用于分析结果的无线传输的发送器31以及具有用于接收分析结果的接收器的显示器4 由基站2发送，显示器29显示分析物浓度值。 本发明将传感器3设置为可更换的传感器壳体单元10的一部分，该传感器壳体单元10具有封闭的壳体12，内部设置有传感器3，并将传感器壳体单元10配合到基站2以便耦合 传感器3到基站2.版权所有（C）2009，JPO＆INPIT

    System for in-vivo measurement of analyte concentration, element exchanging package system thereof, and sensor packaging method
    7.
    发明专利
    System for in-vivo measurement of analyte concentration, element exchanging package system thereof, and sensor packaging method 审中-公开
    用于分析仪浓度的元件测量系统，元件交换包装系统及传感器包装方法

    公开(公告)号：JP2008253751A

    公开(公告)日：2008-10-23

    申请号：JP2008063258

    申请日：2008-03-12

    Applicant: F Hoffmann-La Roche Ag ,  エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト

    Inventor： ROESICKE BERND ,  RASCH-MENGES JUERGEN

    IPC: A61B5/00

    CPC classification number: A61B5/1495 ,  A61B5/150022 ,  A61B2560/0223 ,  A61B2562/242

    Abstract: PROBLEM TO BE SOLVED: To provide a system for measuring the analyte concentration in a human or animal body. SOLUTION: This system includes: an exchangeable sensor 3 for generating a measurement signal showing the analyte concentration; a data carrier 11 with calibration data of the sensor; and a base station 2 to which the sensor 3 and the data carrier 11 are connected, wherein the measurement signal of the sensor 3 can be transferred to an evaluation unit for evaluating the measurement signal of the sensor 3 using the calibration data. The system includes a housing 12 having at least two separate chambers 13, 14, wherein at least one sensor 3 is housed under sterile conditions in the first chamber 13, and the data carrier 11 is housed in the second chamber 14. When the housing 12 is adapted to an interface, the sensor 3 and the data carrier 11 are connected to the base station 2. The invention further relates to a packaging system for replaceable parts, and a method for packaging the sensor 3. COPYRIGHT: (C)2009,JPO&INPIT

    Abstract translation: 要解决的问题：提供一种用于测量人或动物体内的分析物浓度的系统。 解决方案：该系统包括：可交换传感器3，用于产生表示分析物浓度的测量信号; 具有传感器的校准数据的数据载体11; 以及传感器3和数据载体11连接到的基站2，其中传感器3的测量信号可以被传送到用于使用校准数据评估传感器3的测量信号的评估单元。 该系统包括具有至少两个分离室13,14的壳体12，其中至少一个传感器3在无菌条件下容纳在第一室13中，并且数据载体11容纳在第二室14中。当壳体12 适用于接口，传感器3和数据载体11连接到基站2.本发明还涉及一种用于可更换部件的包装系统和一种包装传感器3的方法。版权所有（C） ）2009，JPO＆INPIT

    SYSTEM FOR ANALYZING LIQUID OF LIVING BODY
    9.
    发明专利
    SYSTEM FOR ANALYZING LIQUID OF LIVING BODY 审中-公开

    公开(公告)号：JP2002328080A

    公开(公告)日：2002-11-15

    申请号：JP2002070172

    申请日：2002-03-14

    Applicant: HOFFMANN LA ROCHE

    Inventor： ROESICKE BERND ,  FREY GUENTER

    IPC: G01N15/06 ,  B01L3/00 ,  G01N1/00 ,  G01N1/28 ,  G01N1/36 ,  G01N15/14 ,  G01N33/487 ,  G01N35/02 ,  G01N35/10

    Abstract: PROBLEM TO BE SOLVED: To facilitate an analytical test of a cell suspension liquid of a living body, drastically reduce a required introducing cost, and achieve a result of an accurate analysis in a high level without a complicated operation. SOLUTION: A single-use unit has a diluting chamber (5), a sample preparing apparatus (6) and a measuring chamber (7), and is used for analyzing the cell suspension liquid such as a liquid of the living body particularly blood, urine and semen, etc. The sample preparing apparatus (6) has a preparing member (8) integrally formed from a preparing tubule (13). When the preparing member (8) is located at the first location, one opening (14) of the preparing tubule (13) is connected to a sample injecting zone (17) of the single-use unit (1). When the preparing member (8) is located at the second location, the diluting chamber (5) and the measuring chamber (7) are movably disposed in a chamber (12) for the preparing member so as to be mutually connected through the preparing tubule (13). The measuring chamber (7) is provided with a ventilating valve (35) that the sample and a diluted solution but gas do not pass through, and fully filled with an inflowing liquid (36) without gas bubbles.

    MEDICAL TEST DEVICE AND METHOD FOR THE OPTICAL DETERMINATION OF AN ANALYTE COMPRISING MEANS FOR COMPENSATING THE AMBIENT LIGHT BACKGROUND
    10.
    发明申请
    MEDICAL TEST DEVICE AND METHOD FOR THE OPTICAL DETERMINATION OF AN ANALYTE COMPRISING MEANS FOR COMPENSATING THE AMBIENT LIGHT BACKGROUND 审中-公开
    用于光学确定包含用于补偿环境光的手段的分析仪的医疗测试装置和方法

    公开(公告)号：WO2007009541A8

    公开(公告)日：2007-03-22

    申请号：PCT/EP2006005821

    申请日：2006-06-17

    Applicant: ROCHE DIAGNOSTICS GMBH ,  HOFFMANN LA ROCHE ,  WEHOWSKI FREDERIC ,  ASFOUR JEAN-MICHEL ,  ROESICKE BERND ,  HEBESTREIT KAI ,  LIMBURG BERND

    Inventor： WEHOWSKI FREDERIC ,  ASFOUR JEAN-MICHEL ,  ROESICKE BERND ,  HEBESTREIT KAI ,  LIMBURG BERND

    IPC: G01J1/44 ,  G01J1/42 ,  G01N21/27

    CPC classification number: G01J1/04 ,  G01J1/0214 ,  G01J1/0425 ,  G01J1/1626 ,  G01J1/4204 ,  G01J1/4228 ,  G01J1/44 ,  G01J2001/444 ,  G01N21/274

    Abstract: The invention refers to a Medical test device for the optical determination of a medically important analyte in an aqueous fluid sample, particularly in blood, said test device comprising: a light source (5) for irradiating a sample with primary light (4), a signal lightdetector (10) which provides an analogue measurement signal characterizing the intensity of detected light and which is arranged for detection of secondary light (6) resulting from interaction of primary light (4) with the sample, a base lightdetector (13) which provides an analogue base signal characterizing the intensity of detected light and which is arranged for detection of ambient light (9) , which may contain primary light (4) , analyzing means (15) for analyzing the signals created by the signal lightdetector (10) and the base lightdetector (13) in order to determine the presence and/or concentration of the analyte in the sample. In order to compensate for the part of the measurement signal caused by ambient light (9) , which is detected by the signal lightdetector (10) in addition to secondary light (6) , the signal lightdetector (10) and the base lightdetector (13) are connected to a common line (14) , which leads to the analyzing means (15) , in such a way that the analogue signals created by the lightdetectors (10,13) are subtracted from each other resulting in a compensated analogue signal provided to the analyzing means (15).

    Abstract translation: 本发明涉及用于光学测定含水流体样品中特别是血液中的医学上重要的分析物的医疗测试装置，所述测试装置包括：用于用原始光（4）照射样品的光源（5） 信号光检测器（10），其提供表征检测光的强度的模拟测量信号，并且被布置用于检测由原色光（4）与样品的相互作用产生的二次光（6），基光检测器（13） 模拟基本信号，其表征检测到的光的强度，并且被布置用于检测可能包含初级光的环境光（9）;用于分析由信号光检测器（10）产生的信号的分析装置（15）和 基底光检测器（13），以便确定样品中分析物的存在和/或浓度。 信号光检测器（10）和基准光检测器（13）为了补偿由除了次级光（6）之外的由信号光检测器（10）检测的由环境光（9）引起的部分测量信号， ）连接到公共线路（14），其通向分析装置（15），使得由光检测器（10,13）产生的模拟信号彼此相减，从而产生经补偿的模拟信号 到分析装置（15）。

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