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    SYSTEM FOR ANALYZING LIQUID OF LIVING BODY
    2.
    发明专利
    SYSTEM FOR ANALYZING LIQUID OF LIVING BODY 审中-公开

    公开(公告)号：JP2002328080A

    公开(公告)日：2002-11-15

    申请号：JP2002070172

    申请日：2002-03-14

    Applicant: HOFFMANN LA ROCHE

    Inventor： ROESICKE BERND ,  FREY GUENTER

    IPC: G01N15/06 ,  B01L3/00 ,  G01N1/00 ,  G01N1/28 ,  G01N1/36 ,  G01N15/14 ,  G01N33/487 ,  G01N35/02 ,  G01N35/10

    Abstract: PROBLEM TO BE SOLVED: To facilitate an analytical test of a cell suspension liquid of a living body, drastically reduce a required introducing cost, and achieve a result of an accurate analysis in a high level without a complicated operation. SOLUTION: A single-use unit has a diluting chamber (5), a sample preparing apparatus (6) and a measuring chamber (7), and is used for analyzing the cell suspension liquid such as a liquid of the living body particularly blood, urine and semen, etc. The sample preparing apparatus (6) has a preparing member (8) integrally formed from a preparing tubule (13). When the preparing member (8) is located at the first location, one opening (14) of the preparing tubule (13) is connected to a sample injecting zone (17) of the single-use unit (1). When the preparing member (8) is located at the second location, the diluting chamber (5) and the measuring chamber (7) are movably disposed in a chamber (12) for the preparing member so as to be mutually connected through the preparing tubule (13). The measuring chamber (7) is provided with a ventilating valve (35) that the sample and a diluted solution but gas do not pass through, and fully filled with an inflowing liquid (36) without gas bubbles.

    4.
    发明专利
    未知

    公开(公告)号：AT354439T

    公开(公告)日：2007-03-15

    申请号：AT03025228

    申请日：2003-11-05

    Applicant: HOFFMANN LA ROCHE

    Inventor： FREY GUENTER ,  LADIGES NORBERT DR ,  NOETZEL SIEGFRIED DR ,  ROESICKE BERND

    IPC: G01N33/48 ,  B01L3/00 ,  B01L9/00 ,  G01N1/10 ,  G01N1/28 ,  G01N33/49 ,  B01D39/08 ,  B01D39/20

    Abstract: System to separate and deliver plasma in micro liter quantities comprises separation unit (1) with two zones. System to separate and deliver plasma in micro liter quantities comprises separation unit (1) with two zones. Blood drop(s) (5) are applied to zone (3) which acts as filter to retain corpuscular blood components. Plasma is released to disperse into carrier zone (2) of nonwoven material strip, e.g. of glass fibers, where plasma can be pressed out. Any corpuscular blood components which pass out of filter zone are blocked by transit (6) into carrier zone.

    DISPOSITIVO PARA LA SEPARACION Y DISTRIBUCION DE PLASMA.
    7.
    发明专利
    DISPOSITIVO PARA LA SEPARACION Y DISTRIBUCION DE PLASMA. 未知

    公开(公告)号：ES2280669T3

    公开(公告)日：2007-09-16

    申请号：ES03025228

    申请日：2003-11-05

    Applicant: HOFFMANN LA ROCHE

    Inventor： FREY GUENTER ,  LADIGES NORBERT DR ,  NOETZEL SIEGFRIED DR ,  ROESICKE BERND

    IPC: B01L3/00 ,  G01N33/48 ,  B01D39/08 ,  B01D39/20 ,  B01L9/00 ,  G01N1/10 ,  G01N1/28 ,  G01N33/49

    Abstract: Dispositivo para la separación y distribución de plasma que contiene - un elemento separador (1), que tiene un vellón separador (3) como una primera zona y un vellón de transporte (2) como una segunda zona, y - el elemento separador se dispone en el dispositivo de manera que el usuario puede acceder a la primera zona para la aplicación de la sangre, en el cual cuando la sangre se aplica a la primera zona del elemento separador, el plasma pasa a la segunda zona del elemento separador y los componentes sanguíneos corpusculares quedan básicamente retenidos en la primera zona del elemento separador y - una unidad de descarga (11, 12), la cual después de la separación del plasma, actúa esencialmente en la segunda zona del elemento separador sin que la unidad de descarga influya en la primera zona del elemento separador de manera que el plasma separado sea liberado de la segunda zona del elemento separador y sea descargado a través de un orificio de salida (13) del dispositivo.

    DEVICE FOR SEPARATING AND DISCHARGING PLASMA
    8.
    发明专利
    DEVICE FOR SEPARATING AND DISCHARGING PLASMA 未知

    公开(公告)号：CA2448433A1

    公开(公告)日：2004-05-11

    申请号：CA2448433

    申请日：2003-11-06

    Applicant: HOFFMANN LA ROCHE

    Inventor： FREY GUENTER ,  ROESICKE BERND ,  NOETZEL SIEGFRIED ,  LADIGES NORBERT

    IPC: G01N33/48 ,  B01L3/00 ,  B01L9/00 ,  G01N1/10 ,  G01N1/28 ,  G01N33/49

    Abstract: The invention concerns plasma separation on a microlitre scale. The method/system according to the invention is able to provide plasma in the range of several microlitres within a very short time as it is required for example in modern analyses by carrier-bound test elements. Plasma separation and plasma release is carried out in two separate consecutive steps of the method using the device according to t he invention such that haemolysis during plasma separation can be avoided despi te an accelerated procedure. The device preferably comprises a disposable unit in which the device is characterized by an economical and simple method of production.

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