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公开(公告)号:WO2004050919A3
公开(公告)日:2004-08-26
申请号:PCT/US0338752
申请日:2003-12-04
Applicant: IBM
Inventor: AMONTOV SERGEY , MICHEL BRUNO , SWANSON SALLY , WOLF HEIKO
IPC: G01N33/543 , B01J20/32 , G01N33/551
CPC classification number: B82Y30/00 , G01N33/54353 , G01N2610/00
Abstract: Described is a process for producing a biomolecular monolayer on a biosensor surface comprising the steps of: reacting a biosensor surface with a solution of heterobifunctional reagent having a first functional group and a second functional group, the first functional group being capable of forming a covalent bond to the biosensor surface groups, the second functional group forming a covalent bond with a homobifunctional polymer to obtain a self-assembled monolayer, and thereafter reacting the monolayer with capture molecules.
Abstract translation: 描述了在生物传感器表面上生产生物分子单层的方法,包括以下步骤:使生物传感器表面与具有第一官能团和第二官能团的异双功能试剂溶液反应,第一官能团能够形成共价键 到生物传感器表面基团,第二官能团与均双官能聚合物形成共价键以获得自组装单层,然后使单层与捕获分子反应。
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公开(公告)号:AT526079T
公开(公告)日:2011-10-15
申请号:AT03769815
申请日:2003-11-13
Applicant: IBM
Inventor: AMONTOV SERGEY , DELAMARCHE EMMANUEL , MICHEL BRUNO
IPC: B01J19/00 , C12Q1/68 , G01N33/53 , G01N33/543
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公开(公告)号:AU2003278515A1
公开(公告)日:2004-07-14
申请号:AU2003278515
申请日:2003-11-13
Applicant: IBM
Inventor: DELAMARCHE EMMANUEL , MICHEL BRUNO , AMONTOV SERGEY
IPC: B01J19/00 , C12Q1/68 , G01N33/53 , G01N33/543
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