公开(公告)号：WO2009052179A3

公开(公告)日：2009-07-02

申请号：PCT/US2008079990

申请日：2008-10-15

Applicant: IDEXX LAB INC ,  ANDERSEN PHILIP ,  BEALL MELISSA JANE ,  BUCH JESSE ,  HSIAO KU-CHUAN ,  HUTH STACEY PAZAR ,  KRAH EUGENE REGIS ,  O'BRIEN-GRAFF BARBARA ,  STRONG-TOWNSEND MARILYN I

Inventor： ANDERSEN PHILIP ,  BEALL MELISSA JANE ,  BUCH JESSE ,  HSIAO KU-CHUAN ,  HUTH STACEY PAZAR ,  KRAH EUGENE REGIS ,  O'BRIEN-GRAFF BARBARA ,  STRONG-TOWNSEND MARILYN I

IPC: C07K16/40 ,  C07K14/47 ,  C12N9/20 ,  G01N33/53

CPC classification number: C12N9/20 ,  C07K16/40

Abstract: Isolated nucleic acid molecules having a nucleotide sequence encoding feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Isolated feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Host cells comprising a vector containing the polynucleotide sequences and methods for expressing the polypeptides. The generation of monoclonal antibodies that specifically binds to the feline pancreatic lipase polypeptides, and cell lines secreting the monoclonal antibodies. Methods for determining the presence or amount of feline pancreatic lipase in a biological sample. The methods include using standards or calibrators of recombinant feline pancreatic lipase to quantify the lipase in a sample. Devices and kits for performing methods for detecting feline pancreatic lipase in biological samples.

Abstract translation: 具有编码猫胰脂肪酶多肽，剪接变体，等位基因变体及其片段的核苷酸序列的分离的核酸分子。 分离的猫胰脂肪酶多肽，剪接变体，等位变体及其片段。 宿主细胞包含含有多核苷酸序列的载体和表达多肽的方法。 特异性结合猫胰脂肪酶多肽的单克隆抗体的产生，以及分泌单克隆抗体的细胞系。 确定生物样品中猫胰脂肪酶的存在或量的方法。 所述方法包括使用重组猫胰脂肪酶的标准品或校准物来定量样品中的脂肪酶。 用于检测生物样品中的猫胰脂肪酶的方法的装置和试剂盒。

公开(公告)号：CA2702582C

公开(公告)日：2013-12-24

申请号：CA2702582

申请日：2008-10-15

Applicant: IDEXX LAB INC

Inventor： ANDERSEN PHILIP ,  BEALL MELISSA JANE ,  BUCH JESSE ,  HSIAO KU-CHUAN ,  HUTH STACEY PAZAR ,  KRAH EUGENE REGIS ,  O'BRIEN-GRAFF BARBARA ,  STRONG-TOWNSEND MARILYN I

IPC: C07K16/40 ,  C07K14/47 ,  C12N9/20 ,  G01N33/53

Abstract: Isolated nucleic acid molecules having a nucleotide sequence encoding feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Isolated feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Host cells comprising a vector containing the polynucleotide sequences and methods for expressing the polypeptides. The generation of monoclonal antibodies that specifically binds to the feline pancreatic lipase polypeptides, and cell lines secreting the monoclonal antibodies. Methods for determining the presence or amount of feline pancreatic lipase in a biological sample. The methods include using standards or calibrators of recombinant feline pancreatic lipase to quantify the lipase in a sample. Devices and kits for performing methods for detecting feline pancreatic lipase in biological samples.

公开(公告)号：CA2702582A1

公开(公告)日：2009-04-23

申请号：CA2702582

申请日：2008-10-15

Applicant: IDEXX LAB INC

Inventor： ANDERSEN PHILIP ,  BEALL MELISSA JANE ,  BUCH JESSE ,  HSIAO KU-CHUAN ,  HUTH STACEY PAZAR ,  KRAH EUGENE REGIS ,  O'BRIEN-GRAFF BARBARA ,  STRONG-TOWNSEND MARILYN I

IPC: C07K16/40 ,  C07K14/47 ,  C12N9/20 ,  G01N33/53

Abstract: Isolated nucleic acid molecules having a nucleotide sequence encoding feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Isolated feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Host cells comprising a vector containing the polynucleotide sequences and methods for expressing the polypeptides. The generation of monoclonal antibodies that specifically binds to the feline pancreatic lipase polypeptides, and cell lines secreting the monoclonal antibodies. Methods for determining the presence or amount of feline pancreatic lipase in a biological sample. The methods include using standards or calibrators of recombinant feline pancreatic lipase to quantify the lipase in a sample. Devices and kits for performing methods for detecting feline pancreatic lipase in biological samples.

公开(公告)号：AU2008312575A1

公开(公告)日：2009-04-23

申请号：AU2008312575

申请日：2008-10-15

Applicant: IDEXX LAB INC

Inventor： HSIAO KU-CHUAN ,  BUCH JESSE ,  KRAH EUGENE REGIS ,  HUTH STACEY PAZAR ,  BEALL MELISSA JANE ,  ANDERSEN PHILIP ,  STRONG-TOWNSEND MARILYN I ,  O'BRIEN-GRAFF BARBARA

IPC: C07K14/47 ,  C07K16/40 ,  C12N9/20 ,  G01N33/53

公开(公告)号：AU2008312575B2

公开(公告)日：2012-02-23

申请号：AU2008312575

申请日：2008-10-15

Applicant: IDEXX LAB INC

Inventor： HSIAO KU-CHUAN ,  BUCH JESSE ,  KRAH EUGENE REGIS ,  HUTH STACEY PAZAR ,  BEALL MELISSA JANE ,  ANDERSEN PHILIP ,  STRONG-TOWNSEND MARILYN I ,  O'BRIEN BARBARA

IPC: C07K16/40 ,  C07K14/47 ,  C12N9/20 ,  G01N33/53

Abstract: Isolated nucleic acid molecules having a nucleotide sequence encoding feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Isolated feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Host cells comprising a vector containing the polynucleotide sequences and methods for expressing the polypeptides. The generation of monoclonal antibodies that specifically binds to the feline pancreatic lipase polypeptides, and cell lines secreting the monoclonal antibodies. Methods for determining the presence or amount of feline pancreatic lipase in a biological sample. The methods include using standards or calibrators of recombinant feline pancreatic lipase to quantify the lipase in a sample. Devices and kits for performing methods for detecting feline pancreatic lipase in biological samples.