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    METHODS AND DEVICES FOR DETECTING PANCREATIC LIPASE
    1.
    发明申请
    METHODS AND DEVICES FOR DETECTING PANCREATIC LIPASE 审中-公开
    用于检测胰腺脂肪酶的方法和装置

    公开(公告)号：WO2006060652A3

    公开(公告)日：2006-12-14

    申请号：PCT/US2005043617

    申请日：2005-12-02

    Applicant: IDEXX LAB INC ,  HUTH STACEY PAZAR ,  STRONG-TOWNSEND MARILYN I

    Inventor： HUTH STACEY PAZAR ,  STRONG-TOWNSEND MARILYN I

    IPC: G01N33/53 ,  C12M1/34 ,  C12Q1/34

    CPC classification number: C12Q1/34 ,  G01N2333/918 ,  G01N2800/067

    Abstract: A method and device for determining pancreatic lipase in an animal blood sample. In one aspect, the device includes a compartmentalized container for storing and reacting the reagents for use in the assay. In another aspect, the device include a multilayer device having a spreading layer and reagents layers with dried reagents for detecting pancreatic lipase. The devices also includes a system for the optical determination of a color change in the reaction mixture. The method includes the use of the device to detect pancreatic lipase in samples.

    Abstract translation: 一种用于确定动物血液样品中的胰脂肪酶的方法和装置。 在一个方面，该装置包括用于储存和反应用于测定的试剂的间隔容器。 在另一方面，该装置包括具有铺展层和试剂层的多层装置，其具有用于检测胰脂肪酶的干试剂。 该设备还包括用于光学确定反应混合物中颜色变化的系统。 该方法包括使用该装置来检测样品中的胰脂肪酶。

    FELINE PANCREATIC LIPASE
    2.
    发明申请
    FELINE PANCREATIC LIPASE 审中-公开

    公开(公告)号：WO2009052179A3

    公开(公告)日：2009-07-02

    申请号：PCT/US2008079990

    申请日：2008-10-15

    Applicant: IDEXX LAB INC ,  ANDERSEN PHILIP ,  BEALL MELISSA JANE ,  BUCH JESSE ,  HSIAO KU-CHUAN ,  HUTH STACEY PAZAR ,  KRAH EUGENE REGIS ,  O'BRIEN-GRAFF BARBARA ,  STRONG-TOWNSEND MARILYN I

    Inventor： ANDERSEN PHILIP ,  BEALL MELISSA JANE ,  BUCH JESSE ,  HSIAO KU-CHUAN ,  HUTH STACEY PAZAR ,  KRAH EUGENE REGIS ,  O'BRIEN-GRAFF BARBARA ,  STRONG-TOWNSEND MARILYN I

    IPC: C07K16/40 ,  C07K14/47 ,  C12N9/20 ,  G01N33/53

    CPC classification number: C12N9/20 ,  C07K16/40

    Abstract: Isolated nucleic acid molecules having a nucleotide sequence encoding feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Isolated feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Host cells comprising a vector containing the polynucleotide sequences and methods for expressing the polypeptides. The generation of monoclonal antibodies that specifically binds to the feline pancreatic lipase polypeptides, and cell lines secreting the monoclonal antibodies. Methods for determining the presence or amount of feline pancreatic lipase in a biological sample. The methods include using standards or calibrators of recombinant feline pancreatic lipase to quantify the lipase in a sample. Devices and kits for performing methods for detecting feline pancreatic lipase in biological samples.

    Abstract translation: 具有编码猫胰脂肪酶多肽，剪接变体，等位基因变体及其片段的核苷酸序列的分离的核酸分子。 分离的猫胰脂肪酶多肽，剪接变体，等位变体及其片段。 宿主细胞包含含有多核苷酸序列的载体和表达多肽的方法。 特异性结合猫胰脂肪酶多肽的单克隆抗体的产生，以及分泌单克隆抗体的细胞系。 确定生物样品中猫胰脂肪酶的存在或量的方法。 所述方法包括使用重组猫胰脂肪酶的标准品或校准物来定量样品中的脂肪酶。 用于检测生物样品中的猫胰脂肪酶的方法的装置和试剂盒。

    FELINE PANCREATIC LIPASE
    3.
    发明专利
    FELINE PANCREATIC LIPASE 未知

    公开(公告)号：CA2702582C

    公开(公告)日：2013-12-24

    申请号：CA2702582

    申请日：2008-10-15

    Applicant: IDEXX LAB INC

    Inventor： ANDERSEN PHILIP ,  BEALL MELISSA JANE ,  BUCH JESSE ,  HSIAO KU-CHUAN ,  HUTH STACEY PAZAR ,  KRAH EUGENE REGIS ,  O'BRIEN-GRAFF BARBARA ,  STRONG-TOWNSEND MARILYN I

    IPC: C07K16/40 ,  C07K14/47 ,  C12N9/20 ,  G01N33/53

    Abstract: Isolated nucleic acid molecules having a nucleotide sequence encoding feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Isolated feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Host cells comprising a vector containing the polynucleotide sequences and methods for expressing the polypeptides. The generation of monoclonal antibodies that specifically binds to the feline pancreatic lipase polypeptides, and cell lines secreting the monoclonal antibodies. Methods for determining the presence or amount of feline pancreatic lipase in a biological sample. The methods include using standards or calibrators of recombinant feline pancreatic lipase to quantify the lipase in a sample. Devices and kits for performing methods for detecting feline pancreatic lipase in biological samples.

    FELINE PANCREATIC LIPASE
    4.
    发明专利
    FELINE PANCREATIC LIPASE 未知

    公开(公告)号：CA2702582A1

    公开(公告)日：2009-04-23

    申请号：CA2702582

    申请日：2008-10-15

    Applicant: IDEXX LAB INC

    Inventor： ANDERSEN PHILIP ,  BEALL MELISSA JANE ,  BUCH JESSE ,  HSIAO KU-CHUAN ,  HUTH STACEY PAZAR ,  KRAH EUGENE REGIS ,  O'BRIEN-GRAFF BARBARA ,  STRONG-TOWNSEND MARILYN I

    IPC: C07K16/40 ,  C07K14/47 ,  C12N9/20 ,  G01N33/53

    Abstract: Isolated nucleic acid molecules having a nucleotide sequence encoding feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Isolated feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Host cells comprising a vector containing the polynucleotide sequences and methods for expressing the polypeptides. The generation of monoclonal antibodies that specifically binds to the feline pancreatic lipase polypeptides, and cell lines secreting the monoclonal antibodies. Methods for determining the presence or amount of feline pancreatic lipase in a biological sample. The methods include using standards or calibrators of recombinant feline pancreatic lipase to quantify the lipase in a sample. Devices and kits for performing methods for detecting feline pancreatic lipase in biological samples.

    METHODS AND DEVICES FOR DETECTING PANCREATIC LIPASE
    6.
    发明公开
    METHODS AND DEVICES FOR DETECTING PANCREATIC LIPASE 审中-公开
    方法和设备IDENTIFYING胰脂肪酶

    公开(公告)号：EP1825264A4

    公开(公告)日：2009-05-13

    申请号：EP05852751

    申请日：2005-12-02

    Applicant: IDEXX LAB INC

    Inventor： HUTH STACEY PAZAR ,  STRONG-TOWNSEND MARILYN I

    IPC: C12Q1/34 ,  C12M1/34

    CPC classification number: C12Q1/34 ,  G01N2333/918 ,  G01N2800/067

    Abstract: A method and device for determining pancreatic lipase in an animal blood sample. In one aspect, the device includes a compartmentalized container for storing and reacting the reagents for use in the assay. In another aspect, the device include a multilayer device having a spreading layer and reagents layers with dried reagents for detecting pancreatic lipase. The devices also includes a system for the optical determination of a color change in the reaction mixture. The method includes the use of the device to detect pancreatic lipase in samples.

    Feline pancreatic lipase
    7.
    发明专利
    Feline pancreatic lipase 未知

    公开(公告)号：AU2008312575B2

    公开(公告)日：2012-02-23

    申请号：AU2008312575

    申请日：2008-10-15

    Applicant: IDEXX LAB INC

    Inventor： HSIAO KU-CHUAN ,  BUCH JESSE ,  KRAH EUGENE REGIS ,  HUTH STACEY PAZAR ,  BEALL MELISSA JANE ,  ANDERSEN PHILIP ,  STRONG-TOWNSEND MARILYN I ,  O'BRIEN BARBARA

    IPC: C07K16/40 ,  C07K14/47 ,  C12N9/20 ,  G01N33/53

    Abstract: Isolated nucleic acid molecules having a nucleotide sequence encoding feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Isolated feline pancreatic lipase polypeptides, splice variants, allelic variants, and fragments thereof. Host cells comprising a vector containing the polynucleotide sequences and methods for expressing the polypeptides. The generation of monoclonal antibodies that specifically binds to the feline pancreatic lipase polypeptides, and cell lines secreting the monoclonal antibodies. Methods for determining the presence or amount of feline pancreatic lipase in a biological sample. The methods include using standards or calibrators of recombinant feline pancreatic lipase to quantify the lipase in a sample. Devices and kits for performing methods for detecting feline pancreatic lipase in biological samples.

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