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1.发明申请NUCLEOTIDES AND PEPTIDES CORRESPONDING TO THE CANINE IGE HEAVY CHAIN CONSTANT REGION AND RELATED METHODS 审中-公开与犬类重力链恒定区相关的核苷酸和相关方法
公开(公告)号：WO9730156A3
公开(公告)日：1997-10-09
申请号：PCT/US9702322
申请日：1997-02-14
Applicant: IDEXX LAB INC
Inventor： MERMER BRION , HARRIS RACHEL A , SIEFRING ANN E
IPC: A61K38/00 , C07K16/00 , C12N15/13 , A61K39/395 , C07K1/21 , C07K1/42 , C07K16/85 , C12N5/10 , C12N15/11
CPC classification number: C07K16/00 , A61K38/00 , C07K2319/02
Abstract: Recombinant DNA molecules encoding complete canine IgE heavy chain constant region and the DNA sequence for all six exons of canine IgE are disclosed. The canine IgE heavy chain constant region DNA sequence was isolated using a nested walking procedure that is also disclosed. Also disclosed are peptides encoded by said sequences, including recombinant canine IgE heavy chain peptides produced by prokaryotic or eukaryotic cells. Such peptides are used in methods to treat the manifestation of allergy in dogs. Disclosed are antibodies that bind to peptides disclosed herein, as well as such antibodies for use to treat the manifestations of allergy in dogs.
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公开(公告)号：AU2125697A
公开(公告)日：1997-09-02
申请号：AU2125697
申请日：1997-02-14
Applicant: IDEXX LAB INC
Inventor： MERMER BRION , HARRIS RACHEL A , SIEFRING ANN E
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