公开(公告)号：WO2013106269A3

公开(公告)日：2014-09-04

申请号：PCT/US2013020483

申请日：2013-01-07

Applicant: IDEXX LAB INC

Inventor： CHAN EUGENE ,  NASSIF KEITH

IPC: G01N33/24

CPC classification number: G01N33/573 ,  G01N33/54366 ,  G01N35/00029 ,  G01N2035/00138 ,  G01N2333/918

Abstract: An immunoassay test slide for use in a dry chemistry analytical instrument includes a slide housing or case formed from two matable sections - a slide cover piece and a slide bottom piece. The slide housing defines an interior cavity in which is situated a sheet-like porous carrier matrix. The slide cover piece has an opening formed through the thickness thereof to expose a central portion of the fluid flow matrix so that a precise volume of fluid sample of blood, serum or the like, preferably pre-mixed with a conjugate reagent, and precise volumes of a wash reagent and a substrate (detector reagent), may be deposited on the matrix through the cover opening by a metering device of the analytical instrument.

Abstract translation: 用于干化学分析仪器的免疫测定试验载玻片包括由两个可配置部分形成的滑动壳体或壳体 - 滑动盖片和滑动底部片。 滑动壳体限定内部空腔，其中位于片状多孔载体矩阵中。 滑动盖件具有通过其厚度形成的开口，以暴露流体流动基体的中心部分，使得精确体积的血液，血清等的液体样品优选与共轭试剂预混合，并且精确体积 洗涤剂和底物（检测剂试剂）可以通过分析仪器的计量装置通过盖开口沉积在基质上。

公开(公告)号：WO2009039239A2

公开(公告)日：2009-03-26

申请号：PCT/US2008076788

申请日：2008-09-18

Applicant: IDEXX LAB INC ,  CARPENTER CHARLES ,  FARACE GIOSI ,  FARRELL ROBERT ,  NASSIF KEITH

Inventor： CARPENTER CHARLES ,  FARACE GIOSI ,  FARRELL ROBERT ,  NASSIF KEITH

IPC: G01N33/543 ,  G01N33/52 ,  G01N33/558

CPC classification number: G01N33/525 ,  G01N33/54366 ,  G01N33/558

Abstract: An apparatus, device, and method for laterally moving or assisting in the lateral movement of at least one of a liquid sample and a reagent along a porous carrier matrix is disclosed. The method comprises contacting the matrix with the at least one of the sample and the reagent and exposing the at least one of a liquid sample and a reagent to a centrifugal force, thereby moving or assisting in the lateral movement of the at least one of a liquid sample and a reagent along the porous carrier matrix.

Abstract translation: 公开了一种用于沿着多孔载体基质横向移动或辅助液体样本和试剂中的至少一个的横向移动的设备，装置和方法。 该方法包括使基质与样品和试剂中的至少一种接触，并将液体样品和试剂中的至少一种暴露于离心力，从而移动或帮助使至少一种液体样品和试剂的横向运动 液体样品和沿多孔载体基质的试剂。

公开(公告)号：CA2857522C

公开(公告)日：2020-04-14

申请号：CA2857522

申请日：2013-01-07

Applicant: IDEXX LAB INC

Inventor： CHAN EUGENE ,  NASSIF KEITH

IPC: G01N33/53

Abstract: An immunoassay test slide for use in a dry chemistry analytical instrument includes a slide housing or case formed from two matable sections - a slide cover piece and a slide bottom piece. The slide housing defines an interior cavity in which is situated a sheet-like porous carrier matrix. The slide cover piece has an opening formed through the thickness thereof to expose a central portion of the fluid flow matrix so that a precise volume of fluid sample of blood, serum or the like, preferably pre-mixed with a conjugate reagent, and precise volumes of a wash reagent and a substrate (detector reagent), may be deposited on the matrix through the cover opening by a metering device of the analytical instrument. The bottom piece of the immunoassay test slide is transparent, and the slide is moved by a transport mechanism of the analytical instrument over a reflectometer or a fluorometer for performing reflectance or fluorescence measurements.

公开(公告)号：ES2672268T3

公开(公告)日：2018-06-13

申请号：ES13736046

申请日：2013-01-07

Applicant: IDEXX LAB INC

Inventor： CHAN EUGENE ,  NASSIF KEITH

IPC: G01N35/00 ,  G01N33/543

Abstract: Portaobjetos para pruebas de inmunoanálisis (2), que comprende: - un alojamiento (4), definiendo el alojamiento (4) una cavidad (10); y - una matriz de soporte porosa (12), disponiéndose la matriz de soporte porosa (12) en la cavidad (10) del alojamiento (4) para alojar una muestra de fluido que comprende un analito, o uno o más reactivos líquidos; en el que el alojamiento (4) comprende un lado inferior que se realiza de un material transmisor de luz, un lado superior (74), comprendiendo el lado superior (74) una entalladura (72) para definir por lo menos parcialmente la cavidad (10) destinada a alojar la matriz de soporte porosa (12), un lado frontal (44), un lado posterior (46) opuesto al lado frontal (44), y unos lados laterales opuestos (48), encontrándose la cavidad (10) dispuesta entre los lados frontal y posterior (44, 46) y entre los lados laterales opuestos (48) del alojamiento (4); y en el que el portaobjetos para pruebas (2) comprende, además: una parte de película superior (70), disponiéndose la parte de la película superior (70) en el alojamiento (4) opuesto al lado inferior, y alineada y cubriendo la matriz de soporte porosa (12), presentando la parte de la película superior (70) una abertura (88) realizada a través del espesor de la misma que está comunicada con la cavidad (10) del alojamiento (4) y que está destinada a alojar la muestra de fluido que comprende un analito o uno o más reactivos líquidos, estando la matriz de soporte porosa (12) dispuesta dentro del alojamiento (4) y alineada con la abertura superior (88) realizada en la parte de la película (70) para recibir en la misma la muestra de fluido o el uno o más reactivos líquidos; y en el que el lado superior (74) del alojamiento (4) comprende por lo menos un reborde entallado (80), encontrándose el por lo menos un reborde entallado (80) adyacente a la parte entallada (72) que aloja la matriz de soporte porosa (12), presentando el por lo menos un reborde entallado (80) una superficie superior sobre la que descansa una parte de la superficie inferior de la parte de película superior (70).

公开(公告)号：EP2802869A4

公开(公告)日：2015-12-09

申请号：EP13736046

申请日：2013-01-07

Applicant: IDEXX LAB INC

Inventor： CHAN EUGENE ,  NASSIF KEITH

IPC: G01N33/543

CPC classification number: G01N33/573 ,  G01N33/54366 ,  G01N35/00029 ,  G01N2035/00138 ,  G01N2333/918

Abstract: An immunoassay test slide for use in a dry chemistry analytical instrument includes a slide housing or case formed from two matable sections—a slide cover piece and a slide bottom piece. The slide housing defines an interior cavity in which is situated a sheet-like porous carrier matrix. The slide cover piece has an opening formed through the thickness thereof to expose a central portion of the fluid flow matrix so that a precise volume of fluid sample of blood, serum or the like, preferably pre-mixed with a conjugate reagent, and precise volumes of a wash reagent and a substrate (detector reagent), may be deposited on the matrix through the cover opening by a metering device of the analytical instrument. The bottom piece of the immunoassay test slide is transparent, and the slide is moved by a transport mechanism of the analytical instrument over a reflectometer or a fluorometer for performing reflectance or fluorescence measurements.

Abstract translation: 用于干化学分析仪器的免疫测定试验载玻片包括由两个可配置部分形成的滑动壳体或壳体 - 滑动盖件和滑动底部件。 滑动壳体限定内部空腔，其中位于片状多孔载体矩阵中。 滑动盖件具有通过其厚度形成的开口，以暴露流体流动基体的中心部分，使得精确体积的血液，血清等的流体样品优选与共轭试剂预混合，并且精确体积 洗涤剂和底物（检测剂试剂）可以通过分析仪器的计量装置通过盖开口沉积在基质上。 免疫测定试片的底部是透明的，并且用反射计或荧光计通过分析仪器的输送机构使载玻片移动，以进行反射或荧光测量。

公开(公告)号：AU2013208289B2

公开(公告)日：2016-08-11

申请号：AU2013208289

申请日：2013-01-07

Applicant: IDEXX LAB INC

Inventor： CHAN EUGENE ,  NASSIF KEITH

IPC: G01N33/24

Abstract: An immunoassay test slide for use in a dry chemistry analytical instrument includes a slide housing or case formed from two matable sections - a slide cover piece and a slide bottom piece. The slide housing defines an interior cavity in which is situated a sheet-like porous carrier matrix. The slide cover piece has an opening formed through the thickness thereof to expose a central portion of the fluid flow matrix so that a precise volume of fluid sample of blood, serum or the like, preferably pre-mixed with a conjugate reagent, and precise volumes of a wash reagent and a substrate (detector reagent), may be deposited on the matrix through the cover opening by a metering device of the analytical instrument.

公开(公告)号：AU2013208289A1

公开(公告)日：2014-08-28

申请号：AU2013208289

申请日：2013-01-07

Applicant: IDEXX LAB INC

Inventor： CHAN EUGENE ,  NASSIF KEITH

IPC: C12Q1/00

Abstract: An immunoassay test slide for use in a dry chemistry analytical instrument includes a slide housing or case formed from two matable sections - a slide cover piece and a slide bottom piece. The slide housing defines an interior cavity in which is situated a sheet-like porous carrier matrix. The slide cover piece has an opening formed through the thickness thereof to expose a central portion of the fluid flow matrix so that a precise volume of fluid sample of blood, serum or the like, preferably pre-mixed with a conjugate reagent, and precise volumes of a wash reagent and a substrate (detector reagent), may be deposited on the matrix through the cover opening by a metering device of the analytical instrument. The bottom piece of the immunoassay test slide is transparent, and the slide is moved by a transport mechanism of the analytical instrument over a reflectometer or a fluorometer for performing reflectance or fluorescence measurements.

公开(公告)号：CA2857522A1

公开(公告)日：2013-07-18

申请号：CA2857522

申请日：2013-01-07

Applicant: IDEXX LAB INC

Inventor： CHAN EUGENE ,  NASSIF KEITH

IPC: G01N33/53

Abstract: An immunoassay test slide for use in a dry chemistry analytical instrument includes a slide housing or case formed from two matable sections - a slide cover piece and a slide bottom piece. The slide housing defines an interior cavity in which is situated a sheet-like porous carrier matrix. The slide cover piece has an opening formed through the thickness thereof to expose a central portion of the fluid flow matrix so that a precise volume of fluid sample of blood, serum or the like, preferably pre-mixed with a conjugate reagent, and precise volumes of a wash reagent and a substrate (detector reagent), may be deposited on the matrix through the cover opening by a metering device of the analytical instrument. The bottom piece of the immunoassay test slide is transparent, and the slide is moved by a transport mechanism of the analytical instrument over a reflectometer or a fluorometer for performing reflectance or fluorescence measurements.