公开(公告)号：CA3079011A1

公开(公告)日：2019-04-25

申请号：CA3079011

申请日：2018-10-19

Applicant: IDEXX LAB INC

Inventor： XIE HONGZHI ,  RAMISETTY SREENIVASA RAO ,  YERRAMILLI MURTHY VSN

IPC: G01N33/538 ,  C07K16/44 ,  C12M1/34 ,  G01N33/53

Abstract: The disclosure generally relates to the detection of symmetrical dimethylarginine (SDMA). More particularly, the disclosure relates to the detection of SDMA using a solid phase. The disclosure provides devices, reagents, kits and methods for detecting symmetrical dimethyl arginine (SDMA) in sample, such as a biological sample from an animal. The method includes detecting the presence or amount of SDMA in the sample by using an immunoassay format, such as a competitive immunoassay. The assay includes the use of antibodies to SDMA that are specific for SDMA and that have less affinity for other arginine derivatives.

公开(公告)号：AU2018351349A1

公开(公告)日：2020-04-23

申请号：AU2018351349

申请日：2018-10-19

Applicant: IDEXX LAB INC

Inventor： XIE HONGZHI ,  RAMISETTY SREENIVASA RAO ,  YERRAMILLI MURTHY VSN

IPC: A61P13/12 ,  C07C237/06 ,  C07C279/12 ,  C07K16/00 ,  C07K16/44 ,  C12M1/34

Abstract: The disclosure generally relates to the detection of symmetrical dimethylarginine (SDMA). More particularly, the disclosure relates to the detection of SDMA using a solid phase. The disclosure provides devices, reagents, kits and methods for detecting symmetrical dimethyl arginine (SDMA) in sample, such as a biological sample from an animal. The method includes detecting the presence or amount of SDMA in the sample by using an immunoassay format, such as a competitive immunoassay. The assay includes the use of antibodies to SDMA that are specific for SDMA and that have less affinity for other arginine derivatives.