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公开(公告)号：WO9809600A3
公开(公告)日：1998-04-16
申请号：PCT/US9715033
申请日：1997-08-26
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , SHEN DEKANG , WU GUANLI
CPC classification number: C07F7/0854 , A61K49/1806 , A61K49/223 , A61K51/1227
Abstract: Novel silicon amphiphilic compounds which comprise a silicon residue. The silicon amphiphilic compounds are particularly suitable for use in compositions for diagnostic imaging, such as ultrasound. Compositions of the silicon amphiphilic compounds comprise a gas or gaseous precursor, and may take the form of vesicle compositions, such as micelles or liposomes.
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公开(公告)号：DE69632401T2
公开(公告)日：2005-05-19
申请号：DE69632401
申请日：1996-06-06
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER C , SHEN DEKANG , WU GUANLI
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公开(公告)号：CA2218541A1
公开(公告)日：1996-12-19
申请号：CA2218541
申请日：1996-06-06
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： WU GUANLI , SHEN DEKANG , UNGER EVAN C
IPC: A61K47/48 , A61K45/00 , A61K49/00 , A61K49/22 , C08F220/44 , C08G65/32 , C07K17/08 , A61B8/13 , A61K9/127
Abstract: Novel targeted compositions which may be used for diagnostic and therapeutic use. The compositions may comprise a lipid, a protein or a polymer and a gas, in combination with a targeting ligand. The targeting ligand targets tissues, cells or receptors, including myocardial cells, endothelial cells, epithelial cells, tumor cells and the glycoprotein GPIIbIIIa receptor. The contrast media can be used in conjunction with diagnostic imaging, such as ultrasound, as well as therapeutic applications, such as therapeutic ultrasound.
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公开(公告)号：AU4913896A
公开(公告)日：1996-09-11
申请号：AU4913896
申请日：1996-01-29
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , SHEN DEKANG , WU GUANLI
IPC: C12N15/09 , A61K9/107 , A61K9/127 , A61K38/00 , A61K47/14 , A61K47/16 , A61K48/00 , A61P37/04 , C07C237/10 , C07F9/10 , C07K14/135 , C07K14/50 , C12N15/88 , C07C69/00 , C07C233/00 , C12N15/64 , A61K9/50
Abstract: Cationic lipid compounds which comprise at least two cationic groups. The cationic lipid compounds are particularly suitable for use as carriers in the intracellular delivery of bioactive agents, including pharmaceuticals and genetic material. Compositions of the present cationic lipid compounds include suspensions, emulsions, micelles and liposomes.
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公开(公告)号：AU6270396A
公开(公告)日：1996-12-30
申请号：AU6270396
申请日：1996-06-06
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , SHEN DEKANG , WU GUANLI
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Patent Agency Ranking
公开(公告)号：EP0839125A4
公开(公告)日：2002-10-30
申请号：EP96905351
申请日：1996-01-29
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , SHEN DEKANG , WU GUANLI
IPC: C12N15/09 , A61K9/107 , A61K9/127 , A61K38/00 , A61K47/14 , A61K47/16 , A61K48/00 , A61P37/04 , C07C237/10 , C07F9/10 , C07K14/135 , C07K14/50 , C12N15/88 , C07C69/00 , A61K9/50 , C07C233/00 , C12N15/64
CPC classification number: C07K14/005 , A61K9/1272 , A61K38/00 , A61K48/00 , C07C237/10 , C07C2601/14 , C07F9/10 , C07K14/501 , C12N15/88 , C12N2760/18522 , Y10S436/829 , Y10S977/797 , Y10S977/798 , Y10S977/80 , Y10S977/801 , Y10S977/907
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公开(公告)号：AT265863T
公开(公告)日：2004-05-15
申请号：AT96921486
申请日：1996-06-06
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , SHEN DEKANG , WU GUANLI
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公开(公告)号：AU6971998A
公开(公告)日：1998-11-27
申请号：AU6971998
申请日：1998-04-15
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , SHEN DEKANG
Abstract: The present invention is directed to novel lipid soluble steroid prodrugs, compositions comprising steroid prodrugs, and uses of the same.
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公开(公告)号：AU678724B2
公开(公告)日：1997-06-05
申请号：AU3053695
申请日：1995-09-08
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , SHEN DEKANG
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公开(公告)号：EP0831932A4
公开(公告)日：2000-01-12
申请号：EP96921486
申请日：1996-06-06
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER EVAN C , SHEN DEKANG , WU GUANLI
CPC classification number: B82Y5/00 , A61K49/0002 , A61K49/223 , A61K49/227 , A61K49/228
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