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公开(公告)号：DE69718519D1
公开(公告)日：2003-02-20
申请号：DE69718519
申请日：1997-08-26
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER C
Abstract: A method for providing an image of an internal region of a patient has been developed. The method reduces imaging artifacts by providing enhanced contrast between tissue and blood during imaging. The method comprises administering to a patient a contrast agent in combination with a renal vasodilator and performing ultrasound imaging of the region. Renal disease, including renal arterial stenosis, may be diagnosed using the method.
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公开(公告)号：DE69835692D1
公开(公告)日：2006-10-05
申请号：DE69835692
申请日：1998-02-25
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER C
Abstract: The present invention is directed to charged lipids, compositions comprising charged lipids, and the use of these compositions in drug delivery, targeted drug delivery, therapeutic imaging and diagnostic imaging, as well as their use as contrast agents.
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公开(公告)号：DE69831755T2
公开(公告)日：2006-07-13
申请号：DE69831755
申请日：1998-12-17
Applicant: IMARX PHARMACEUTICAL CORP
Abstract: The present invention generally relates to optoacoustic contrast agents and methods of diagnostic and therapeutic imaging using optoacoustic contrast agents.
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公开(公告)号：DE69632401T2
公开(公告)日：2005-05-19
申请号：DE69632401
申请日：1996-06-06
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER C , SHEN DEKANG , WU GUANLI
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公开(公告)号：DE69718519T2
公开(公告)日：2003-11-06
申请号：DE69718519
申请日：1997-08-26
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER C
Abstract: A method for providing an image of an internal region of a patient has been developed. The method reduces imaging artifacts by providing enhanced contrast between tissue and blood during imaging. The method comprises administering to a patient a contrast agent in combination with a renal vasodilator and performing ultrasound imaging of the region. Renal disease, including renal arterial stenosis, may be diagnosed using the method.
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Patent Agency Ranking
公开(公告)号：DE69736981D1
公开(公告)日：2007-01-04
申请号：DE69736981
申请日：1997-04-30
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER C , MCCREERY THOMAS
IPC: A01N43/04 , C12N15/09 , A61K9/127 , A61K31/70 , A61K41/00 , A61K45/08 , A61K47/02 , A61K47/18 , A61K47/30 , A61K47/42 , A61K48/00 , A61P3/10 , A61P7/00 , A61P9/10 , A61P11/00 , A61P21/00 , A61P31/18 , A61P35/00 , C07H21/04 , C12N5/10 , C12N15/12 , C12N15/85 , C12N15/87 , C12N15/88 , C12P21/02
Abstract: The present invention is directed, inter alia, to a method for delivering a compound into a cell comprising administering to the cell the compound to be delivered, an organic halide, and/or a carrier. Ultrasound may also be applied, if desired.
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公开(公告)号：DE69629478T2
公开(公告)日：2004-06-17
申请号：DE69629478
申请日：1996-06-06
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER C , MCCREERY THOMAS , YELLOWHAIR DAVID , BARRETTE R
IPC: A61K49/00 , A61B5/055 , A61B8/00 , A61J3/00 , A61K8/14 , A61K8/70 , A61K9/127 , A61K41/00 , A61K47/48 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B01F3/04 , B01F11/00 , B01F15/00
Abstract: A method and apparatus for making vesicles suitable for use as contrast agents in which a container containing an aqueous suspension phase and a separate gas phase is shaken using reciprocating motion. The reciprocating motion is produced by a shaker arm that moves the container in two, substantially perpendicular directions, with the motion in the first direction being along an arcuate path. The overall path of the motion occurs in a figure-8 eight pattern. The frequency of shaking is at least approximately 2800 RPM, the length of the shaker arm is at least approximately 6 cm, and the angle through which the shaker arm rotates in the first direction is at least approximately 3 DEG . The total length of travel around the figure-8 pattern is at least 0.7 cm.
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公开(公告)号：DE69831755D1
公开(公告)日：2006-02-09
申请号：DE69831755
申请日：1998-12-17
Applicant: IMARX PHARMACEUTICAL CORP
Abstract: The present invention generally relates to optoacoustic contrast agents and methods of diagnostic and therapeutic imaging using optoacoustic contrast agents.
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公开(公告)号：DE69533261T2
公开(公告)日：2005-08-04
申请号：DE69533261
申请日：1995-07-26
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER C , MATSUNAGA O , YELLOWHAIR DAVID
IPC: G01R33/28 , A61B5/055 , A61J1/00 , A61K8/04 , A61K8/14 , A61K8/70 , A61K9/127 , A61K9/133 , A61K41/00 , A61K47/48 , A61K49/00 , A61K49/18 , A61K49/22 , A61M5/31 , A61Q19/00 , B65D81/20
Abstract: A container comprising an aqueous lipid suspension and a gaseous phase substantially separate from the aqueous stabilizing phase, useful in diagnostic imaging such as ultrasound and magnetic resonance imaging and in therapeutic applications, is disclosed.
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公开(公告)号：DE69632401D1
公开(公告)日：2004-06-09
申请号：DE69632401
申请日：1996-06-06
Applicant: IMARX PHARMACEUTICAL CORP
Inventor： UNGER C , SHEN DEKANG , WU GUANLI
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