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    NOVEL METHODS OF IMAGING AND TREATMENT WITH TARGETED COMPOSITIONS
    1.
    发明申请
    NOVEL METHODS OF IMAGING AND TREATMENT WITH TARGETED COMPOSITIONS 审中-公开
    用靶向成分进行成像和处理的新方法

    公开(公告)号：WO0045856A3

    公开(公告)日：2001-02-15

    申请号：PCT/US0002620

    申请日：2000-02-02

    Applicant: IMARX PHARMACEUTICAL CORP

    Inventor： UNGR EVAN C ,  WU YUNQIU

    IPC: A61B8/00 ,  A61B8/08 ,  A61K49/00 ,  A61K49/22

    CPC classification number: A61K49/225 ,  A61K49/223 ,  A61K49/227 ,  A61K49/228 ,  B82Y5/00

    Abstract: Novel ultrasound methods comprising administering to a patient a targeted vesicle composition which comprises vesicles comprising a lipid, protein or polymer, encapsulating a gas, in combination with a targeting ligand, and scanning the patient using ultrasound. The scanning may comprise exposing the patient to a first type of ultrasound energy and then interrogating the patient using a second type of ultrasound energy. The targeting ligand preferably targets tissus, cells or receptors, including myocardial cells, endothelial cells, epithelial cells, tumor cells and the glycoprotein GPIIbIIIa receptor. The methods may be used to detect a thrombus, enhancement of an old or echogenic thrombus low concentrations of vesicles and vesicles targeted to tissues, cells or receptors.

    Abstract translation: 新型超声方法包括向患者施用靶向囊泡组合物，其包含包含脂质，蛋白质或聚合物的囊泡，包封气体，与靶向配体组合，以及使用超声波扫描患者。 扫描可以包括将患者暴露于第一类型的超声能量，然后使用第二类型的超声能量来询问患者。 靶向配体优选靶向组织，细胞或受体，包括心肌细胞，内皮细胞，上皮细胞，肿瘤细胞和糖蛋白GPIIbIIIa受体。 该方法可用于检测血栓，增强靶向组织，细胞或受体的老的或回声血栓低浓度的囊泡和囊泡。

    2.
    发明专利
    未知

    公开(公告)号：DE69831755T2

    公开(公告)日：2006-07-13

    申请号：DE69831755

    申请日：1998-12-17

    Applicant: IMARX PHARMACEUTICAL CORP

    Inventor： UNGER C ,  WU YUNQIU

    IPC: A61B8/13 ,  A61K41/00 ,  A61K49/00

    Abstract: The present invention generally relates to optoacoustic contrast agents and methods of diagnostic and therapeutic imaging using optoacoustic contrast agents.

    Novel methods of imaging and treatment with targeted compositions
    3.
    发明专利
    Novel methods of imaging and treatment with targeted compositions 未知

    公开(公告)号：AU777304B2

    公开(公告)日：2004-10-07

    申请号：AU3586600

    申请日：2000-02-02

    Applicant: IMARX PHARMACEUTICAL CORP

    Inventor： UNGR EVAN C ,  WU YUNQIU

    IPC: A61B8/00 ,  A61B8/08 ,  A61K49/00 ,  A61K49/22

    Abstract: Novel ultrasound methods comprising administering to a patient a targeted vesicle composition which comprises vesicles comprising a lipid, protein or polymer, encapsulating a gas, in combination with a targeting ligand, and scanning the patient using ultrasound. The scanning may comprise exposing the patient to a first type of ultrasound energy and then interrogating the patient using a second type of ultrasound energy. The targeting ligand preferably targets tissues, cells or receptors, including myocardial cells, endothelial cells, epithelial cells, tumor cells and the glycoprotein GPIIbIIIa receptor. The methods may be used to detect a thrombus, enhancement of an old or echogenic thrombus, low concentrations of vesicles and vesicles targeted to tissues, cells or receptors.

    9.
    发明专利
    未知

    公开(公告)号：DE69831755D1

    公开(公告)日：2006-02-09

    申请号：DE69831755

    申请日：1998-12-17

    Applicant: IMARX PHARMACEUTICAL CORP

    Inventor： UNGER C ,  WU YUNQIU

    IPC: A61B8/13 ,  A61K41/00 ,  A61K49/00

    Abstract: The present invention generally relates to optoacoustic contrast agents and methods of diagnostic and therapeutic imaging using optoacoustic contrast agents.

    NOVEL METHODS OF IMAGING AND TREATMENT WITH TARGETED COMPOSITIONS
    10.
    发明专利
    NOVEL METHODS OF IMAGING AND TREATMENT WITH TARGETED COMPOSITIONS 未知

    公开(公告)号：CA2362200A1

    公开(公告)日：2000-08-10

    申请号：CA2362200

    申请日：2000-02-02

    Applicant: IMARX PHARMACEUTICAL CORP

    Inventor： WU YUNQIU ,  UNGER EVAN C

    IPC: A61B8/00 ,  A61B8/08 ,  A61K49/00 ,  A61K49/22

    Abstract: Novel ultrasound methods comprising administering to a patient a targeted vesicle composition which comprises vesicles comprising a lipid, protein or polymer, encapsulating a gas, in combination with a targeting ligand, and scanning the patient using ultrasound. The scanning may comprise exposing th e patient to a first type of ultrasound energy and then interrogating the patient using a second type of ultrasound energy. The targeting ligand preferably targets tissus, cells or receptors, including myocardial cells, endothelial cells, epithelial cells, tumor cells and the glycoprotein GPIIbIIIa receptor. The methods may be used to detect a thrombus, enhancemen t of an old or echogenic thrombus low concentrations of vesicles and vesicles targeted to tissues, cells or receptors.

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