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公开(公告)号：FI62207C
公开(公告)日：1982-12-10
申请号：FI770285
申请日：1977-01-28
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： MUHLER JOSEPH C , KLEBER CARL J , KELLY RAY G
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公开(公告)号：FI62207B
公开(公告)日：1982-08-31
申请号：FI770285
申请日：1977-01-28
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： MUHLER JOSEPH C , KLEBER CARL J , KELLY RAY G
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公开(公告)号：NO781156L
公开(公告)日：1978-10-05
申请号：NO781156
申请日：1978-04-03
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： MUHLER JOSEPH C , KLEBER CARL J , KELLY RAY G KIRKWOOD MO
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公开(公告)号：NO781156A
公开(公告)日：1978-10-05
申请号：NO781156
申请日：1978-04-03
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： MUHLER JOSEPH C , KLEBER CARL J , KELLY RAY G KIRKWOOD MO
IPC: A23G3/34 , A23G3/00 , A23G3/36 , A23L29/00 , A61K8/00 , A61K8/20 , A61K8/23 , A61K8/26 , A61K8/34 , A61K8/36 , A61K8/362 , A61K8/60 , A61K8/73 , A61Q11/00 , A23L
CPC classification number: A23G3/368 , A23L29/015
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公开(公告)号：AU549059B2
公开(公告)日：1986-01-09
申请号：AU8106882
申请日：1982-03-03
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： MUHLER JOSEPH C , KLEBER CARL J , REAM RONALD L , MOORE DAVID M
Abstract: A chewing gum is disclosed which is for cleaning and imparting a high degree of polish to the teeth; the chewing gum comprises a chewing gum base, at least one non-toxic source of acid in a particular amount, and calcined kaolin particles, the median diameter of which is approximately 2 micrometres or less, and substantially all of the particles being less than approximately 20 micrometres in diameter. Such a chewing gum cleans and imparts a high degree of polish to the teeth without unduly abrading or scratching them, When regularly chewed, such a gum, in addition to cleaning and polishing the dental enamel, can also inhibit the reformation of dental plaque.
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Patent Agency Ranking
公开(公告)号：CA1188619A
公开(公告)日：1985-06-11
申请号：CA397049
申请日：1982-02-25
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： MUHLER JOSEPH C , KLEBER CARL J , REAM RONALD L , MOORE DAVID M
Abstract: An improved chewing gum capable of cleaning and imparting a high degree of polish to the teeth comprises a chewing gum base, at least one non-toxic source of acid, and calcined kaolin particles, the median diameter of which is about 2 micrometers or less, substantially all of the particles being less than about 20 micrometers in diameter. Such a chewing gum cleans and imparts a high degree of polish to the teeth without unduly abrading or scratching them. When regularly chewed, such a gum, in addition to cleaning and polishing the dental enamel, also inhibits the reformation of dental plaque.
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公开(公告)号：CA1083592A
公开(公告)日：1980-08-12
申请号：CA283451
申请日：1977-07-25
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： MUHLER JOSEPH C , PUTT MARK S , KLEBER CARL J , YOHO CLAYTON W
IPC: C07C59/245 , A61K8/00 , A61K8/25 , A61K8/36 , A61K8/365 , A61K33/06 , A61P17/00 , A61Q11/00 , C07C51/00 , C07C67/00 , C07F5/06
Abstract: ANTICARIOGENIC MALOALUMINATE COMPLEXES Aqueous anionic maloaluminate complexes of the structure: at mildly alkaline ph are effective in reducing the incidence and severity of dental caries. These complexes may be advantageously incorporated in aqueous oral compositions, especially dentifrices, having pH values lying in the range or about 7.0 - 9.0.
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公开(公告)号：FI781011A
公开(公告)日：1978-10-05
申请号：FI781011
申请日：1978-04-03
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： MUHLER JOSEPH C , KLEBER CARL J , KELLY RAY G
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公开(公告)号：AU2177277A
公开(公告)日：1978-08-03
申请号：AU2177277
申请日：1977-01-28
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： MUHLER JOSEPH C , KLEBER CARL J , KELLY RAY G
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公开(公告)号：DE2734648A1
公开(公告)日：1978-02-09
申请号：DE2734648
申请日：1977-08-01
Applicant: INDIANA UNIVERSITY FOUNDATION
Inventor： MUHLER JOSEPH C , PUTT MARK S , KLEBER CARL J , YOHO CLAYTON W
IPC: C07C59/245 , A61K8/00 , A61K8/25 , A61K8/36 , A61K8/365 , A61K33/06 , A61P17/00 , A61Q11/00 , C07C51/00 , C07C67/00 , C07F5/06 , C07C59/12 , A61K7/24
Abstract: Aqueous anionic maloaluminate complexes of the structure: at mildly alkaline pH are effective in reducing the incidence and severity of dental caries. These complexes may be advantageously incorporated in aqueous oral compositions, especially dentifrices, having pH values lying in the range of about 7.0 - 9.0.
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