公开(公告)号：AU563606B2

公开(公告)日：1987-07-16

申请号：AU1539583

申请日：1983-06-06

Applicant: INDIANA UNIVERSITY FOUNDATION

Inventor： MUHLER JOSEPH C ,  PUTT MARK S

IPC: A61K8/00 ,  A61K8/21 ,  A61K8/22 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61Q11/00 ,  A61K7/16 ,  A61K7/18

Abstract: Incorporation of talc in dentifrice preparations based on calcined kaolins enhances the rheological properties of such dentifrices. In addition, new and more effective dentifrice preparations may be obtained by employing therein a cleaning and polishing constituent comprising a mixture of calcined kaolin, talc and titanium dioxide. Additionally, anticariogenic adjuvants, such as sodium fluoride and stannous fluoride, especially a 1:2 molar mixture thereof, may be incorporated in such dentifrice preparations.

公开(公告)号：CA1222955A

公开(公告)日：1987-06-16

申请号：CA430963

申请日：1983-06-22

Applicant: INDIANA UNIVERSITY FOUNDATION

Inventor： MUHLER JOSEPH C ,  PUTT MARK S

IPC: A61K8/00 ,  A61K8/21 ,  A61K8/22 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61Q11/00 ,  A61K7/16

Abstract: Incorporation of talc in dentifrice preparations based on calcined kaolins enhances the rheological properties of such dentifrices. In addition, new and more effective dentifrice preparations may be obtained by employing therein a cleaning and polishing constituent comprising a mixture of calcined kaolin, talc and titanium dioxide. Additionally, anticariogenic adjuvants, such as sodium fluoride and stannous fluoride, especially a 1:2 molar mixture thereof, may be incorporated in such dentifrice preparations.

公开(公告)号：ZA8304225B

公开(公告)日：1984-03-28

申请号：ZA8304225

申请日：1983-06-09

Applicant: INDIANA UNIVERSITY FOUNDATION

Inventor： MUHLER JOSEPH C ,  PUTT MARK S

IPC: A61K8/00 ,  A61K8/21 ,  A61K8/22 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61Q11/00 ,  A61K

CPC classification number: A61Q11/00 ,  A61K8/26

公开(公告)号：AU1539583A

公开(公告)日：1984-01-05

申请号：AU1539583

申请日：1983-06-06

Applicant: INDIANA UNIVERSITY FOUNDATION

Inventor： MUHLER JOSEPH C ,  PUTT MARK S

IPC: A61K8/00 ,  A61K8/21 ,  A61K8/22 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61Q11/00 ,  A61K7/16 ,  A61K7/18

Abstract: Incorporation of talc in dentifrice preparations based on calcined kaolins enhances the rheological properties of such dentifrices. In addition, new and more effective dentifrice preparations may be obtained by employing therein a cleaning and polishing constituent comprising a mixture of calcined kaolin, talc and titanium dioxide. Additionally, anticariogenic adjuvants, such as sodium fluoride and stannous fluoride, especially a 1:2 molar mixture thereof, may be incorporated in such dentifrice preparations.

公开(公告)号：CA1154682A

公开(公告)日：1983-10-04

申请号：CA373119

申请日：1981-03-16

Applicant: INDIANA UNIVERSITY FOUNDATION

Inventor： MUHLER JOSEPH C ,  PUTT MARK S

IPC: A61K8/22 ,  A61K8/25 ,  A61K8/26 ,  A61Q11/00 ,  C09C1/28 ,  A61K7/16

Abstract: DWVl1-G/D -33- The application discloses new dental prophylactic cleaning and polishing agents comprising magnesium silicate particles obtained by thermally treating naturally-occurring or synthetic magnesium silicates.

公开(公告)号：CA1083592A

公开(公告)日：1980-08-12

申请号：CA283451

申请日：1977-07-25

Applicant: INDIANA UNIVERSITY FOUNDATION

Inventor： MUHLER JOSEPH C ,  PUTT MARK S ,  KLEBER CARL J ,  YOHO CLAYTON W

IPC: C07C59/245 ,  A61K8/00 ,  A61K8/25 ,  A61K8/36 ,  A61K8/365 ,  A61K33/06 ,  A61P17/00 ,  A61Q11/00 ,  C07C51/00 ,  C07C67/00 ,  C07F5/06

Abstract: ANTICARIOGENIC MALOALUMINATE COMPLEXES Aqueous anionic maloaluminate complexes of the structure: at mildly alkaline ph are effective in reducing the incidence and severity of dental caries. These complexes may be advantageously incorporated in aqueous oral compositions, especially dentifrices, having pH values lying in the range or about 7.0 - 9.0.

公开(公告)号：DE2734648A1

公开(公告)日：1978-02-09

申请号：DE2734648

申请日：1977-08-01

Applicant: INDIANA UNIVERSITY FOUNDATION

Inventor： MUHLER JOSEPH C ,  PUTT MARK S ,  KLEBER CARL J ,  YOHO CLAYTON W

IPC: C07C59/245 ,  A61K8/00 ,  A61K8/25 ,  A61K8/36 ,  A61K8/365 ,  A61K33/06 ,  A61P17/00 ,  A61Q11/00 ,  C07C51/00 ,  C07C67/00 ,  C07F5/06 ,  C07C59/12 ,  A61K7/24

Abstract: Aqueous anionic maloaluminate complexes of the structure: at mildly alkaline pH are effective in reducing the incidence and severity of dental caries. These complexes may be advantageously incorporated in aqueous oral compositions, especially dentifrices, having pH values lying in the range of about 7.0 - 9.0.

公开(公告)号：DE3381488D1

公开(公告)日：1990-05-31

申请号：DE3381488

申请日：1983-06-22

Applicant: INDIANA UNIVERSITY FOUNDATION

Inventor： MUHLER JOSEPH CHARLES ,  PUTT MARK S

IPC: A61K8/00 ,  A61K8/21 ,  A61K8/22 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61Q11/00 ,  A61K7/16 ,  A61K7/18

Abstract: Incorporation of talc in dentifrice preparations based on calcined kaolins enhances the rheological properties of such dentifrices. In addition, new and more effective dentifrice preparations may be obtained by employing therein a cleaning and polishing constituent comprising a mixture of calcined kaolin, talc and titanium dioxide. Additionally, anticariogenic adjuvants, such as sodium fluoride and stannous fluoride, especially a 1:2 molar mixture thereof, may be incorporated in such dentifrice preparations.

公开(公告)号：AT52183T

公开(公告)日：1990-05-15

申请号：AT83303588

申请日：1983-06-22

Applicant: INDIANA UNIVERSITY FOUNDATION

Inventor： MUHLER JOSEPH CHARLES ,  PUTT MARK S

IPC: A61K8/00 ,  A61K8/21 ,  A61K8/22 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61Q11/00 ,  A61K7/16 ,  A61K7/18

Abstract: Incorporation of talc in dentifrice preparations based on calcined kaolins enhances the rheological properties of such dentifrices. In addition, new and more effective dentifrice preparations may be obtained by employing therein a cleaning and polishing constituent comprising a mixture of calcined kaolin, talc and titanium dioxide. Additionally, anticariogenic adjuvants, such as sodium fluoride and stannous fluoride, especially a 1:2 molar mixture thereof, may be incorporated in such dentifrice preparations.

公开(公告)号：ZA834225B

公开(公告)日：1984-03-28

申请号：ZA834225

申请日：1983-06-09

Applicant: INDIANA UNIVERSITY FOUNDATION

Inventor： MUHLER JOSEPH C ,  PUTT MARK S

IPC: A61K8/00 ,  A61K8/21 ,  A61K8/22 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61Q11/00 ,  A61K

Abstract: Incorporation of talc in dentifrice preparations based on calcined kaolins enhances the rheological properties of such dentifrices. In addition, new and more effective dentifrice preparations may be obtained by employing therein a cleaning and polishing constituent comprising a mixture of calcined kaolin, talc and titanium dioxide. Additionally, anticariogenic adjuvants, such as sodium fluoride and stannous fluoride, especially a 1:2 molar mixture thereof, may be incorporated in such dentifrice preparations.