公开(公告)号：EP0304151B1

公开(公告)日：1993-12-15

申请号：EP88306087.3

申请日：1988-07-04

Applicant: INSTRUMENTATION LABORATORY S.p.A.

Inventor： Musacchio, John ,  Premoli, Pietro ,  Manzoni, Angelo ,  Bergkuist, Carolyn

IPC: G01N33/84

CPC classification number: G01N33/84

公开(公告)号：EP0304151A3

公开(公告)日：1990-09-12

申请号：EP88306087.3

申请日：1988-07-04

Applicant: INSTRUMENTATION LABORATORY S.p.A.

Inventor： Musacchio, John ,  Premoli, Pietro ,  Manzoni, Angelo ,  Bergkuist, Carolyn

IPC: G01N33/84

CPC classification number: G01N33/84

Abstract: A method for determining the concentrations of total calcium and at least one monovalent ion in a sample includes the steps of mixing the sample with a diluent that has a pH within the range pH 6.5 to 7.0 and includes 2-amino-2-hydroxymethyl-1,3 propanediol phosphate and is free of the monovalent ion. An aliquot of the diluted sample is concurrently contacted with a calcium-specific ion selective electrode and an ion selective electrode specifically responsive to the monovalent ion, the response of the calcium-specific ion selective electrode is measured as an indication of the concentration of total calcium in the sample, and the response of the monovalent ion specific ion selective electrode is measured as an indication of the concentration of the monovalent ion in the sample.

公开(公告)号：EP0304151A2

公开(公告)日：1989-02-22

申请号：EP88306087.3

申请日：1988-07-04

Applicant: INSTRUMENTATION LABORATORY S.p.A.

Inventor： Musacchio, John ,  Premoli, Pietro ,  Manzoni, Angelo ,  Bergkuist, Carolyn

IPC: G01N33/84

CPC classification number: G01N33/84

Abstract: A method for determining the concentrations of total calcium and at least one monovalent ion in a sample includes the steps of mixing the sample with a diluent that has a pH within the range pH 6.5 to 7.0 and includes 2-amino-2-hydroxymethyl-1,3 propanediol phosphate and is free of the monovalent ion. An aliquot of the diluted sample is concurrently contacted with a calcium-specific ion selective electrode and an ion selective electrode specifically responsive to the monovalent ion, the response of the calcium-specific ion selective electrode is measured as an indication of the concentration of total calcium in the sample, and the response of the monovalent ion specific ion selective electrode is measured as an indication of the concentration of the monovalent ion in the sample.

Abstract translation: 用于确定样品中总钙和至少一种一价离子浓度的方法包括以下步骤：将样品与pH在6.5至7.0范围内的pH值的稀释剂混合并包括2-氨基-2-羟甲基-1 ，3丙二醇磷酸酯，不含一价离子。 稀释的样品的等分试样同时与钙离子选择性电极和对单价离子特异性响应的离子选择性电极同时接触，测量钙离子选择性电极的响应作为总钙浓度的指示 在样品中，并且测量一价离子特异性离子选择电极的响应作为样品中一价离子浓度的指示。