公开(公告)号：WO2014149486A1

公开(公告)日：2014-09-25

申请号：PCT/US2014/018868

申请日：2014-02-27

Applicant: ISP INVESTMENTS INC.

Inventor： CHUANG, Jui-Chang ,  LIU, Xuejun ,  MUSA, Osama M. ,  STREULI, David C.

IPC: C08F26/08 ,  C08F26/10

CPC classification number: C08F226/10 ,  A61K8/046 ,  A61K8/8182 ,  A61K2800/10 ,  A61Q5/06 ,  A61Q17/04 ,  A61Q19/00 ,  C08F26/08 ,  C08F220/06 ,  C08F220/18 ,  C08F220/56 ,  C08F220/58 ,  C08F222/10

Abstract: family of non-homopolymers synthesized from N-vinyl lactam, (meth)acrylic acid, hydrophobic (meth)acrylic ester of a straightchain or branched-chain alkyl alcohol and monomer selected from the group consisting of functionalized and unfunctionalized: dialkyi maleates, dialkyi fumarates, and combinations thereof. The non-homopolymers may exhibit solubility in one or more lowermolecular weight alcohols and/or a glass transition temperature greater than 80?C.

Abstract translation: 由N-乙烯基内酰胺，（甲基）丙烯酸，直链或支链烷基醇的疏水（甲基）丙烯酸酯和选自官能化和未官能化的单体合成的非均聚物家族：马来酸二烷基酯，富马酸二烷基酯 ，及其组合。 非均聚物可以在一种或多种低分子量醇中显示溶解度和/或大于80℃的玻璃化转变温度。

公开(公告)号：WO2013134755A1

公开(公告)日：2013-09-12

申请号：PCT/US2013/030115

申请日：2013-03-11

Applicant: ISP INVESTMENTS INC.

Inventor： MUSA, Osama, M. ,  LIU, Xuejun ,  CHUANG, Jui-Chang ,  WINKOWSKI, Karen

IPC: C08G63/48

CPC classification number: C08G81/021 ,  A01N43/36 ,  A61K8/8164 ,  A61K8/91 ,  A61K2800/524 ,  A61K2800/74 ,  A61Q17/005 ,  A61Q19/00 ,  C08F26/06 ,  C08G63/48

Abstract: Provided are multifunctional polymers comprising at least one anhydride repeating unit with at least one pseudo-cationic moiety graft and at least one hydrophobic graft. The grafting functionalizations can occur before, during, or after polymerizing the monomer(s). The anhydride employed may be partially or fully opened to provide amic acids, carboxylic acids, carboxylic acidic salts, imides, esters, and mixtures thereof. The polymers also may comprise other repeating units, including, but not limited to, alpha-olefins. In one embodiment the polymers exhibit antimicrobial activity, and can be employed in a wide variety of compositions, including those where antimicrobial activity is useful. A method of providing microbial activity also is provided.

Abstract translation: 提供了包含至少一个酸酐重复单元与至少一个假阳离子部分接枝和至少一个疏水性接枝的多官能聚合物。 接枝官能化可以在聚合单体之前，之中或之后进行。 所使用的酸酐可以部分或全部开放，以提供酰胺酸，羧酸，羧酸盐，酰亚胺，酯及其混合物。 聚合物还可以包含其它重复单元，包括但不限于α-烯烃。 在一个实施方案中，聚合物表现出抗微生物活性，并且可以用于多种组合物中，包括其中抗微生物活性是有用的组合物。 还提供了提供微生物活性的方法。

公开(公告)号：WO1994001472A1

公开(公告)日：1994-01-20

申请号：PCT/US1993004832

申请日：1993-05-20

Applicant: ISP INVESTMENTS INC.

Inventor： ISP INVESTMENTS INC. ,  PLOCHOCKA, Krystyna ,  SHIH, Jenn, S. ,  CHUANG, Jui-Chang

IPC: C08F06/00

CPC classification number: C08F6/006 ,  C08F8/00 ,  C08L39/00 ,  C08F226/10

Abstract: A process is described for rendering amino-group-containing polymer solutions substantially odorless. A solution of the terpolymer of vinyl pyrrolidone, vinyl caprolactam and dimethylaminoethyl methacrylate, for example, is treated with 0.1-10 % by weight of an acidic compound, or an acidic ion-exchange resin, to render the solution substantially odorless.

Abstract translation: 描述了使含有氨基的聚合物溶液基本无臭的方法。 乙烯基吡咯烷酮，乙烯基己内酰胺和甲基丙烯酸二甲氨基乙酯三元共聚物的溶液用0.1-10重量％的酸性化合物或酸性离子交换树脂处理，使溶液基本上无臭。

公开(公告)号：WO2003004541A1

公开(公告)日：2003-01-16

申请号：PCT/US2002/015855

申请日：2002-05-17

Applicant: ISP INVESTMENTS INC.

Inventor： CHUANG, Jui-Chang ,  SHIH, Jenn, S. ,  DRZEWINSKI, Michael, A.

IPC: C08F26/08

CPC classification number: C08F271/00 ,  C08F26/06

Abstract: A process of making a vinyl caprolactam (VCL)-based polymer which comprises suspension polymerizing the monomers in aqueous medium in the absence of an added protective colloid, wherein polymer formed at an early stage of the polymerization functions as a dispersing agent to maintain polymer particules suspended in water throughout the polymerization.

Abstract translation: 制备基于乙烯基己内酰胺（VCL）的聚合物的方法，其包括在不存在添加的保护胶体的情况下使单体在水性介质中的悬浮聚合，其中在聚合反应初期形成的聚合物用作分散剂以维持聚合物颗粒 在聚合过程中悬浮在水中。

公开(公告)号：WO1993021931A1

公开(公告)日：1993-11-11

申请号：PCT/US1993003835

申请日：1993-04-23

Applicant: ISP INVESTMENTS INC.

Inventor： ISP INVESTMENTS INC. ,  SHIH, Jenn, S. ,  MERIANOS, John, J. ,  SMITH, Terry, E. ,  CHUANG, Jui-Chang ,  HALDAR, Rama, K.

IPC: A61K31/79

CPC classification number: A01N59/00 ,  A01N59/12 ,  C08F8/00 ,  A01N25/10 ,  A01N2300/00 ,  C08F26/10

Abstract: Strongly swellable, moderately crosslinked polyvinylpyrrolidone polymer in the form of fine white powders having a defined aqueous gel volume and Brookfield viscosity which is prepared by precipitation polymerization in the presence of a prescribed amount of a crosslinking agent, and an effective amount of a pharmaceutical medicament, or hydrogen peroxide or iodine in the form of a complex, is described herein.

Abstract translation: 强溶胀性中等交联聚乙烯吡咯烷酮聚合物，其为具有限定水凝胶体积和布氏粘度形式的细白色粉末，其通过在规定量的交联剂存在下的沉淀聚合制备，以及有效量的药物， 或复合物形式的过氧化氢或碘。

公开(公告)号：WO1993009763A1

公开(公告)日：1993-05-27

申请号：PCT/US1992009821

申请日：1992-11-10

Applicant: ISP INVESTMENTS INC.

Inventor： ISP INVESTMENTS INC. ,  CHAUDHURI, Ratan, K. ,  JAISWAL, Dinesh, K. ,  HALDAR, Rama, K. ,  LOGIN, Robert, B. ,  TAZI, Mohammed ,  CHUANG, Jui-Chang

IPC: A61K09/14

CPC classification number: A61K9/2027

Abstract: A pharmaceutical tablet is provided herein having an effective dissolution rate. The tablet contains a pharmaceutically-active ingredient and a substantially linear, i.e. non-crosslinked K-30 to K-120 PVP, preferably above 116, as a binding agent. The PVP used herein preferably is made by a polymerization process in which the vinyl pyrrolidone monomer is polymerized in the presence of an initiator which produces a linear PVP polymerization, and a residual initiator level of less than 500 ppm.

Abstract translation: 本文提供了具有有效溶解速率的药片。 片剂含有药物活性成分和基本上线性的，即非交联的K-30至K-120 PVP，优选高于116，作为结合剂。 本文使用的PVP优选通过聚合方法制备，其中乙烯基吡咯烷酮单体在产生线性PVP聚合的引发剂存在下聚合，残余引发剂水平低于500ppm。

公开(公告)号：WO1992013014A1

公开(公告)日：1992-08-06

申请号：PCT/US1991006781

申请日：1991-09-19

Applicant: ISP INVESTMENTS INC.

Inventor： ISP INVESTMENTS INC. ,  CHUANG, Jui-Chang ,  WALLS, Edward, W., Jr. ,  JOHNSON, Stephen, C.

IPC: C08F218/04

CPC classification number: C08F218/04 ,  A61K8/8158 ,  A61Q5/06

Abstract: A hair spray fixative resin comprises a vinyl acetate/alkyl maleate half ester/N-substituted acrylamide terpolymer in a molar ratio of about 1.0 to 0.6-0.8 to 0.08-0.12, which is preferably produced by a suspension or solution polymerization process. Utilizing N-substituted acrylamides in place of isoborneol methacrylates in the terpolymer provides superior holding power over conventional hair fixative resins, at lower cost.

公开(公告)号：EP0648231A1

公开(公告)日：1995-04-19

申请号：EP93914046.0

申请日：1993-05-20

Applicant: ISP INVESTMENTS INC.

Inventor： PLOCHOCKA, Krystyna ,  SHIH, Jenn, S. ,  CHUANG, Jui-Chang

IPC: C08F6 ,  C08F8

CPC classification number: C08F6/006 ,  C08F8/00 ,  C08L39/00 ,  C08F226/10

Abstract: A process is described for rendering amino-group-containing polymer solutions substantially odorless. A solution of the terpolymer of vinyl pyrrolidone, vinyl caprolactam and dimethylaminoethyl methacrylate, for example, is treated with 0.1-10 % by weight of an acidic compound, or an acidic ion-exchange resin, to render the solution substantially odorless.

公开(公告)号：WO2013162766A1

公开(公告)日：2013-10-31

申请号：PCT/US2013/032219

申请日：2013-03-15

Applicant: ISP INVESTMENTS INC.

Inventor： CHUANG, Jui-Chang ,  LIU, Xuejun ,  MUSA, Osama, M. ,  WINKOWSKI, Karen

IPC: C08L33/26

CPC classification number: C08F226/10 ,  A01N43/36 ,  C08F220/18 ,  C08F220/60 ,  C08F226/08

Abstract: Described herein are multifunctional polymers comprising a first repeating unit having at least one pseudo-cationic moiety, a second repeating unit having at least a hydrophobic moiety, and a third repeating unit, where the weight-average molecular weight is less than about 10,000 Da. In one embodiment the polymers exhibit antimicrobial activity. Also provided are compositions formulated with the multifunctional polymers, and a method of providing antimicrobial activity.

Abstract translation: 本文描述的是包含具有至少一个假阳离子部分的第一重复单元，至少具有疏水部分的第二重复单元和第三重复单元的多官能聚合物，其中重均分子量小于约10,000Da。 在一个实施方案中，聚合物表现出抗微生物活性。 还提供了用多功能聚合物配制的组合物，以及提供抗微生物活性的方法。

公开(公告)号：WO2005118658A1

公开(公告)日：2005-12-15

申请号：PCT/US2005/010414

申请日：2005-03-29

Applicant: ISP INVESTMENTS INC. ,  CHUANG, Jui-Chang ,  JACHOWICZ, Janusz ,  WINKLER, Thomas ,  KRAUSS, Allen, J.

Inventor： CHUANG, Jui-Chang ,  JACHOWICZ, Janusz ,  WINKLER, Thomas ,  KRAUSS, Allen, J.

IPC: C08F26/08

CPC classification number: A61Q19/00 ,  A61K8/8182 ,  A61Q5/04 ,  A61Q5/06 ,  A61Q5/08 ,  A61Q5/10 ,  A61Q5/12 ,  A61Q17/04 ,  A61Q19/08 ,  A61Q19/10 ,  C08F2/10 ,  C08F8/06 ,  C08F226/06 ,  C08F2800/20 ,  C08F2810/50 ,  C08F226/10 ,  C08F220/60 ,  C08F2220/603

Abstract: What is described herein are conditioning/styling tetrapolymers of vinyl caprolactam (VCL), vinylpyrrolidone (VP), dimethylaminopropyl methacrylamide (DMAPMA) and C 8 -C 24 alkyl quaternized dimethylaminopropyl (meth)acrylamide or methacrylic acid quaternized monomers (QDMAPMA), in a defined compositional range. Hair and skin care compositions which include these tetrapolymers exhibit advantageous low tackiness and high humidity resistance.

Abstract translation: 本文描述的是定义的组合物中的乙烯基己内酰胺（VCL），乙烯基吡咯烷酮（VP），二甲基氨基丙基甲基丙烯酰胺（DMAPMA）和C 8 -C 24烷基季铵化二甲基氨基丙基（甲基）丙烯酰胺或甲基丙烯酸季铵化单体（QDMAPMA） 范围。 包括这些四元共聚物的头发和皮肤护理组合物显示出有利的低粘性和高耐湿性。