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    SUNSCREEN COMPOSITION
    2.
    发明申请
    SUNSCREEN COMPOSITION 审中-公开
    SUNSCREEN组合物

    公开(公告)号：WO1993002117A1

    公开(公告)日：1993-02-04

    申请号：PCT/US1992005653

    申请日：1992-07-06

    Applicant: ISP INVESTMENTS, INC.

    Inventor： ISP INVESTMENTS, INC. ,  KWAK, Yoon, T. ,  KOPOLOW, Stephen, L. ,  HELIOFF, Michael, W. ,  TAZI, Mohammed

    IPC: C08F225/08

    CPC classification number: A61Q5/06 ,  A61K8/8164 ,  A61Q17/04 ,  C08F216/14 ,  C08F222/06

    Abstract: What is provided herein is a sunscreen composition consisting essentially of a crosslinked, neutralized terpolymer of maleic anhydride, a C1-C5 alkyl vinyl ether and a C12-C14 alpha-olefin monomer as a thickener; water; an ultraviolet sunscreening agent; and an emulsifier. In the prefered form of the invention, the monomers are present in a molar ratio of about 1:0.90-0.99:0.01-0.10, respectively, and are crosslinked with about 2-8 wt.% of a crosslinking agent based on the total weight of the monomers. Suitably, the crosslinked terpolymer is neutralized to increase water solubility.

    Abstract translation: 本文提供的防晒组合物主要由交联的中和的马来酸酐三元共聚物，C 1 -C 5烷基乙烯基醚和作为增稠剂的C 12 -C 14α-烯烃单体组成。 水; 紫外线防晒剂; 和乳化剂。 在本发明的优选形式中，单体分别以约1:0.90-0.99:0.01至0.10的摩尔比存在，并以基于总重量的约2-8重量％的交联剂进行交联 的单体。 适当地，交联的三元共聚物被中和以增加水溶性。

    CHARGE IMBALANCED POLYELECTROLYTE COMPOSITION
    3.
    发明申请
    CHARGE IMBALANCED POLYELECTROLYTE COMPOSITION 审中-公开
    电荷不均匀聚电解质组合物

    公开(公告)号：WO1993011170A1

    公开(公告)日：1993-06-10

    申请号：PCT/US1992008251

    申请日：1992-09-30

    Applicant: ISP INVESTMENTS INC.

    Inventor： ISP INVESTMENTS INC. ,  CHAUDHURI, Ratan, K. ,  LOGIN, Robert, B. ,  ANDERSON, Lowell, R. ,  TAZI, Mohammed

    IPC: C08F08/32

    CPC classification number: C08F8/12 ,  C08F2810/50 ,  C08F8/48 ,  C08F8/32 ,  C08F222/06 ,  C08F216/18

    Abstract: A charge imbalanced composition comprising: (a) about 10 to 90 mole % of an amphoteric copolymer having formula (I) where R = alkyl C1-C4, n = 1-6, R1 and R2 are independently alkyl C1-C6, and R3 is H; (b) about 10 to 90 mole % of a polymeric diacid having formula (II) where R is as defined above, and (c) less than about 8 mole % of by-product salts which are the dialkylaminoalkylamine salts of (a) and (b). The composition described above is made by: reacting 1 mole of an anhydride compound having formula (III) where R is as defined above, with less than 1 mole of a compound having formula (IV) where n, R1 and R2 are as defined above, and R3 is H, isolating the product, and hydrolyzing residual anhydride compound in water to the corresponding diacid compound.

    BENZENE-FREE MALEIC ANHYDRIDE/VINYL ETHER POLYMERS
    7.
    发明申请
    BENZENE-FREE MALEIC ANHYDRIDE/VINYL ETHER POLYMERS 审中-公开
    无苯乙烯/乙烯基醚聚合物

    公开(公告)号：WO1993001220A1

    公开(公告)日：1993-01-21

    申请号：PCT/US1992005131

    申请日：1992-06-17

    Applicant: ISP INVESTMENTS INC.

    Inventor： ISP INVESTMENTS INC. ,  COHEN, Jeffrey, M. ,  COYLE, Laurie, A. ,  TAZI, Mohammed ,  ZAMORA, John, N.

    IPC: C08F34/02

    CPC classification number: C08F222/06 ,  C08F216/18

    Abstract: A process for the manufacture of benzene-free maleic anhydride/lower alkyl vinyl ether polymer having a specific viscosity ranging from about 1.0 to about 5.5 by premixing maleic anhydride and the alkyl vinyl ether in a mole ratio of between about 1:1.1 and about 1:2 in a cosolvent mixture of lower alkyl substituted benzene, a C6-8 alkane, a saturated lower alkyl ether with a lower alkyl vinyl ether as cosolvent and reacting the monomeric complexed mixture at elevated temperature and pressure in continuous contact with a peroxide initiator wherein the specific viscosity is controlled by adjusting the amount of lower alkyl vinyl ether in the cosolvent mixture. The polymeric product is recovered from the resulting slurry by vacuum drying.

    Abstract translation: 通过将马来酸酐和烷基乙烯基醚以约1:1至约1:1的摩尔比预混合制备具有约1.0至约5.5的比粘度的无苯基马来酸酐/低级烷基乙烯基醚聚合物的方法 ：在低级烷基取代的苯，C6-8烷烃，饱和低级烷基醚与低级烷基乙烯基醚作为共溶剂的共溶剂混合物中2，使单体络合混合物在升高的温度和压力下与过氧化物引发剂连续接触， 通过调节共溶剂混合物中的低级烷基乙烯基醚的量来控制比粘度。 通过真空干燥从所得浆料中回收聚合物。

    PRODUCTION OF AN ETHANOL SOLUTION OF ETHYL OR BUTYL HALF-ESTER OF A COPOLYMER
    9.
    发明申请
    PRODUCTION OF AN ETHANOL SOLUTION OF ETHYL OR BUTYL HALF-ESTER OF A COPOLYMER 审中-公开
    乙醇或叔丁基醚共聚物的乙醇溶液的生产

    公开(公告)号：WO1993019126A1

    公开(公告)日：1993-09-30

    申请号：PCT/US1993001399

    申请日：1993-02-18

    Applicant: ISP INVESTMENTS, INC.

    Inventor： ISP INVESTMENTS, INC. ,  ZAMORA, John, N. ,  CARLIN, Alan, J. ,  TAZI, Mohammed

    IPC: C08L31/00

    CPC classification number: C08F8/14

    Abstract: A process for the production of an ethanol solution of an ethyl or butyl alkyl half-ester copolymer of maleic anhydride and an alkyl vinyl ether which comprises: (a) copolymerizing the monomers in acetone as solvent by simultaneously feeding molten maleic anhydride, a molar excess of methyl vinyl ether, and a solution of a free radical initiator in acetone, into a reactor precharged with acetone, at about 68-85 °C, preferably 70-80 °C; (b) esterifying the acetone solution of said copolymer with ethanol or butanol; and (c) solvent exchanging ethanol for acetone by continuously injecting vapors of ethanol at about 85-95°C into said copolymer solution while simultaneously distilling out acetone therefrom at atmospheric pressure.

    PHARMACEUTICAL TABLET WITH PVP HAVING AN ENHANCED DRUG DISSOLUTION RATE
    10.
    发明申请
    PHARMACEUTICAL TABLET WITH PVP HAVING AN ENHANCED DRUG DISSOLUTION RATE 审中-公开
    具有增强药物溶解速率的PVP的药物片

    公开(公告)号：WO1993009763A1

    公开(公告)日：1993-05-27

    申请号：PCT/US1992009821

    申请日：1992-11-10

    Applicant: ISP INVESTMENTS INC.

    Inventor： ISP INVESTMENTS INC. ,  CHAUDHURI, Ratan, K. ,  JAISWAL, Dinesh, K. ,  HALDAR, Rama, K. ,  LOGIN, Robert, B. ,  TAZI, Mohammed ,  CHUANG, Jui-Chang

    IPC: A61K09/14

    CPC classification number: A61K9/2027

    Abstract: A pharmaceutical tablet is provided herein having an effective dissolution rate. The tablet contains a pharmaceutically-active ingredient and a substantially linear, i.e. non-crosslinked K-30 to K-120 PVP, preferably above 116, as a binding agent. The PVP used herein preferably is made by a polymerization process in which the vinyl pyrrolidone monomer is polymerized in the presence of an initiator which produces a linear PVP polymerization, and a residual initiator level of less than 500 ppm.

    Abstract translation: 本文提供了具有有效溶解速率的药片。 片剂含有药物活性成分和基本上线性的，即非交联的K-30至K-120 PVP，优选高于116，作为结合剂。 本文使用的PVP优选通过聚合方法制备，其中乙烯基吡咯烷酮单体在产生线性PVP聚合的引发剂存在下聚合，残余引发剂水平低于500ppm。

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