公开(公告)号：WO1997009965A1

公开(公告)日：1997-03-20

申请号：PCT/US1996011387

申请日：1996-06-25

Applicant: ISP INVESTMENTS INC.

Inventor： ISP INVESTMENTS INC. ,  TSENG, Susan, Y. ,  CHUANG, Jui-Chang ,  WOLF, Philip, F. ,  HELIOFF, Michael, W. ,  KRUMMEL, H., Karl ,  DAVIS, Mary, R.

IPC: A61K09/14

CPC classification number: A61K8/042 ,  A61K8/0241 ,  A61K8/365 ,  A61K8/368 ,  A61K8/8176 ,  A61K8/8182 ,  A61K31/19 ,  A61K31/194 ,  A61K31/20 ,  A61K31/60 ,  A61K2800/75 ,  A61Q5/00 ,  A61Q5/08 ,  A61Q19/00 ,  A61Q19/02

Abstract: This invention relates to an acidic non-irritating lotion, cream or ointment for rejuvenating skin and hair which comprises a micronized, homogenized hydrogen of a cross-linked N-vinyl lactam polymer and an organic rejuvenating agent selected from the group consisting of pyruvic acid, a mono- or poly- carboxylated C1 to C20 hydrocarbon optionally substituted with from 1 to 3 hydroxy groups and ammonium and alkali metal salts of said acids and mixtures thereof including mixtures of the acids and/or said salts. The invention also relates to a cross-linked N-vinyl lactam polymer in the form of a stable, homogenized flowable hydrogel having microparticles which can be passed through a screen of between about 40 and about 350 mesh size and to the process for the preparation of the homogenized gel and to its use as a hair and skin conditioner or as a carrier for a cosmetically or pharmaceutically active substance.

Abstract translation: 本发明涉及一种酸性非刺激性洗剂，用于使皮肤和毛发恢复嫩肤的霜剂或软膏，其包含交联的N-乙烯基内酰胺聚合物的微粉化均化氢和选自丙酮酸， 任选被1至3个羟基取代的单羧基化或多羧基化的C 1至C 20烃，以及所述酸的铵和碱金属盐及其混合物，包括酸和/或所述盐的混合物。 本发明还涉及一种具有稳定的，均匀的可流动水凝胶形式的交联的N-乙烯基内酰胺聚合物，其具有可以通过约40至约350目尺寸的筛网的微粒，以及制备 均质化凝胶及其用作头发和皮肤调理剂或用作化妆品或药物活性物质的载体。