公开(公告)号：AU2009239471B2

公开(公告)日：2013-01-24

申请号：AU2009239471

申请日：2009-04-21

Applicant: JANSSEN PHARMACEUTICA NV

Inventor： WIENER DANIELLE ,  LEBSACK ALEC DONALD ,  LEENAERTS JOSEPH ELISABETH ,  RECH JASON CHRISTOPHER ,  VENABLE JENNIFER DIANE ,  COOYMANS LUDWIG PAUL ,  SMITH DEBORAH MARGARET ,  BREITENBUCHER JAMES GUY ,  LOVE CHRISTOPHER JOHN ,  GLEASON ELIZABETH ANN ,  BRANSTETTER BRYAN JAMES

IPC: C07D401/14 ,  A61K31/4427 ,  C07D405/14 ,  C07D413/14

Abstract: The present invention is related to novel compounds of formula (I) having P2X7 antagonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with P2X7 receptor activity in animals, in particular humans. (I)

公开(公告)号：CA2722035C

公开(公告)日：2016-10-11

申请号：CA2722035

申请日：2009-04-21

Applicant: JANSSEN PHARMACEUTICA NV

Inventor： LOVE CHRISTOPHER JOHN ,  LEENAERTS JOSEPH ELISABETH ,  COOYMANS LUDWIG PAUL ,  LEBSACK ALEC DONALD ,  BRANSTETTER BRYAN JAMES ,  RECH JASON CHRISTOPHER ,  GLEASON ELIZABETH ANN ,  VENABLE JENNIFER DIANE ,  WIENER DANIELLE ,  SMITH DEBORAH MARGARET ,  BREITENBUCHER JAMES GUY

IPC: C07D401/14 ,  A61K31/4427 ,  C07D405/14 ,  C07D413/14

Abstract: The present invention is related to novel compounds of formula (I) having P2X7 antagonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with P2X7 receptor activity in animals, in particular humans. (I)

公开(公告)号：CA2722035A1

公开(公告)日：2009-10-29

申请号：CA2722035

申请日：2009-04-21

Applicant: JANSSEN PHARMACEUTICA NV

Inventor： LOVE CHRISTOPHER JOHN ,  LEENAERTS JOSEPH ELISABETH ,  COOYMANS LUDWIG PAUL ,  LEBSACK ALEC DONALD ,  BRANSTETTER BRYAN JAMES ,  RECH JASON CHRISTOPHER ,  GLEASON ELIZABETH ANN ,  VENABLE JENNIFER DIANE ,  WIENER DANIELLE ,  SMITH DEBORAH MARGARET ,  BREITENBUCHER JAMES GUY

IPC: C07D401/14 ,  A61K31/4427 ,  C07D405/14 ,  C07D413/14

Abstract: The present invention is related to novel compounds of formula (I) having P2X7 antagonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with P2X7 receptor activity in animals, in particular humans. (I)

公开(公告)号：AU2009239471A1

公开(公告)日：2009-10-29

申请号：AU2009239471

申请日：2009-04-21

Applicant: JANSSEN PHARMACEUTICA NV

Inventor： LOVE CHRISTOPHER JOHN ,  RECH JASON CHRISTOPHER ,  LEBSACK ALEC DONALD ,  VENABLE JENNIFER DIANE ,  BRANSTETTER BRYAN JAMES ,  SMITH DEBORAH MARGARET ,  BREITENBUCHER JAMES GUY ,  GLEASON ELIZABETH ANN ,  LEENAERTS JOSEPH ELISABETH ,  COOYMANS LUDWIG PAUL ,  WIENER DANIELLE

IPC: C07D401/14 ,  A61K31/4427 ,  C07D405/14 ,  C07D413/14

Abstract: The present invention is related to novel compounds of formula (I) having P2X7 antagonistic properties, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment or prophylaxis of diseases associated with P2X7 receptor activity in animals, in particular humans. (I).