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公开(公告)号：AT277005T
公开(公告)日：2004-10-15
申请号：AT98935265
申请日：1998-07-29
Applicant: KANEKA CORP
Inventor： UEDA YASUYOSHI , MAEHARA KATSUJI , SUGAWA TADASHI , MURAO HIROSHI , NISHIYAMA AKIRA , MANABE HAJIME
IPC: C07C319/28 , C07C323/25
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公开(公告)号：DE69620363D1
公开(公告)日：2002-05-08
申请号：DE69620363
申请日：1996-06-19
Applicant: KANEKA CORP
Inventor： SUGAWA TADASHI , INOUE KENJI
Abstract: A process for producing optically active 1-halo-3-amino-4-phenyl-2-butanol derivatives from optically active 1-halo-3-amino-4-phenyl-2-butanone derivatives stereoselectively in a high yield by bringing the butanone derivatives into contact with microorganisms.
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公开(公告)号：DE69826448T2
公开(公告)日：2005-09-22
申请号：DE69826448
申请日：1998-07-29
Applicant: KANEKA CORP
Inventor： UEDA YASUYOSHI , MAEHARA KATSUJI , SUGAWA TADASHI , MURAO HIROSHI , NISHIYAMA AKIRA , MANABE HAJIME
IPC: C07C319/28 , C07C323/25
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公开(公告)号：DE69826448D1
公开(公告)日：2004-10-28
申请号：DE69826448
申请日：1998-07-29
Applicant: KANEKA CORP
Inventor： UEDA YASUYOSHI , MAEHARA KATSUJI , SUGAWA TADASHI , MURAO HIROSHI , NISHIYAMA AKIRA , MANABE HAJIME
IPC: C07C319/28 , C07C323/25
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公开(公告)号：ES2185967T3
公开(公告)日：2003-05-01
申请号：ES97935797
申请日：1997-08-18
Applicant: KANEKA CORP
Inventor： MATSUMOTO SHINGO , MATSUO KAZUHIKO , SUGAWA TADASHI , MOROSHIMA TADASHI , INOUE KENJI
IPC: C07C227/02 , C07C227/42 , C07C229/22 , C07C229/34 , C07C229/36 , C07C269/08 , C07C271/18 , C07C271/22 , C07C303/40 , C07C303/44 , C07C311/19 , C07D209/26 , C07D209/48
Abstract: An object of the present invention is to provide a process for producing a beta -amino- alpha -hydroxy acid derivative via efficient and industrially utilizable steps. The present invention provides a process for producing a beta -amino- alpha -hydroxy acid derivative represented by the general formula (2) given below which comprises hydrolyzing an alpha -amino- alpha ', alpha '-dihaloketone derivative of the general formula (1) given below in the presence of a base, followed by protecting the amino group or without protecting the same.
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Patent Agency Ranking
公开(公告)号：ES2176463T3
公开(公告)日：2002-12-01
申请号：ES96918833
申请日：1996-06-19
Applicant: KANEKA CORP
Inventor： SUGAWA TADASHI , INOUE KENJI
Abstract: A process for producing optically active 1-halo-3-amino-4-phenyl-2-butanol derivatives from optically active 1-halo-3-amino-4-phenyl-2-butanone derivatives stereoselectively in a high yield by bringing the butanone derivatives into contact with microorganisms.
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公开(公告)号：DE69616446T2
公开(公告)日：2002-05-16
申请号：DE69616446
申请日：1996-02-02
Applicant: KANEKA CORP
Inventor： NISHIYAMA AKIRA , SUGAWA TADASHI , MANABE HAJIME , INOUE KENJI , YOSHIDA NORITAKA
IPC: C07C29/143 , C07C45/48 , C07C269/06 , C07C319/20 , C07C323/43 , C07D303/36 , C07C49/80 , C07C33/46 , C07C221/00 , C07C225/16 , C07C213/00 , C07C215/28 , C07D301/26 , C07D303/04
Abstract: Processes for efficiently producing alpha -halo ketones, alpha -halohydrins and epoxides on an industrial scale. The prosesses include one for producing an alpha -halo ketone of general formula (3) by decarboxylating a product of reaction between a carboxilic acid derivative of general formula (1) and a metal enolate prepared from an alpha -haloacetic acid of general formula (2) or an acceptable salt thereof, one for producing an by reducing the alpha -halo ketone (3), and one for producing an epoxide (13) by treating the alpha -halohydrin (11) with a base to effect ring closure. The above prosesses are particularly suitable for producing optically active alpha -halo ketones, alpha -halohydrins and epoxides from the corresponding alpha -amino acid derivatives. R COA
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公开(公告)号：DE69716452D1
公开(公告)日：2002-11-21
申请号：DE69716452
申请日：1997-08-18
Applicant: KANEKA CORP
Inventor： MATSUMOTO SHINGO , MATSUO KAZUHIKO , SUGAWA TADASHI , MOROSHIMA TADASHI , INOUE KENJI
IPC: C07C227/02 , C07C227/42 , C07C229/22 , C07C229/34 , C07C229/36 , C07C269/08 , C07C271/18 , C07C271/22 , C07C303/40 , C07C303/44 , C07C311/19 , C07D209/26 , C07D209/48
Abstract: An object of the present invention is to provide a process for producing a beta -amino- alpha -hydroxy acid derivative via efficient and industrially utilizable steps. The present invention provides a process for producing a beta -amino- alpha -hydroxy acid derivative represented by the general formula (2) given below which comprises hydrolyzing an alpha -amino- alpha ', alpha '-dihaloketone derivative of the general formula (1) given below in the presence of a base, followed by protecting the amino group or without protecting the same.
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公开(公告)号：IN184528B
公开(公告)日：2000-09-02
申请号：IN6CA1998
申请日：1998-01-01
Applicant: KANEKA CORP
Inventor： NISHIYAMA AKIRA , SUGAWA TADASHI , MANABE HAJIME , INOUE KENJI , YOSHIDA NORITAKA
IPC: C07D301/27
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公开(公告)号：IN184446B
公开(公告)日：2000-08-26
申请号：IN1293CA1998
申请日：1998-07-24
Applicant: KANEKA CORP
Inventor： UEDA YOSUYOSHI , MAEHARA KATSUJI , SUGAWA TADASHI , MURAO HIROSHI , NISHIYAMA AKIRA , MANABE HAJIME
IPC: C07C319/28 , C07C323/25 , A61K31/00
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