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公开(公告)号：AT419844T
公开(公告)日：2009-01-15
申请号：AT01902822
申请日：2001-02-09
Applicant: KAO CORP
Inventor： NAGASHIMA YOSHINAO , SUGATA KEIICHI , YADA YUKIHIRO , FUKUDA KAZUYUKI
Abstract: The autonomic nerve regulating agent of the present invention, which has a sedative action, sleep inducing action, and stress mitigating action in individuals, regardless of individual variation in sensitivity to or preference for fragrance, contains as an active ingredient a sesquiterpene alcohol with a boiling point of 250 DEG C or higher, particularly cedrol.
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公开(公告)号：DE60137285D1
公开(公告)日：2009-02-26
申请号：DE60137285
申请日：2001-02-09
Applicant: KAO CORP
Inventor： NAGASHIMA YOSHINAO , SUGATA KEIICHI , YADA YUKIHIRO , FUKUDA KAZUYUKI
Abstract: The autonomic nerve regulating agent of the present invention, which has a sedative action, sleep inducing action, and stress mitigating action in individuals, regardless of individual variation in sensitivity to or preference for fragrance, contains as an active ingredient a sesquiterpene alcohol with a boiling point of 250 DEG C or higher, particularly cedrol.
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公开(公告)号：EP1170005A4
公开(公告)日：2004-10-20
申请号：EP01902822
申请日：2001-02-09
Applicant: KAO CORP
Inventor： NAGASHIMA YOSHINAO , SUGATA KEIICHI , YADA YUKIHIRO , FUKUDA KAZUYUKI
IPC: A61K9/00 , A61K31/045 , A61K31/05 , A61P25/02 , A61P25/20 , A61K7/46 , A61L9/03 , A61L9/16 , A61L9/22
CPC classification number: A61K31/045 , A61K9/007
Abstract: The autonomic nerve regulating agent of the present invention, which has a sedative action, sleep inducing action, and stress mitigating action in individuals, regardless of individual variation in sensitivity to or preference for fragrance, contains as an active ingredient a sesquiterpene alcohol with a boiling point of 250 DEG C or higher, particularly cedrol.
Abstract translation: 本发明的具有镇静作用，睡眠诱导作用和减轻紧张作用的本发明的自主神经调节剂，无论对于香味的敏感性或偏爱性的个体变化如何，均含有沸腾的倍半萜醇作为活性成分 点在250℃以上，特别是雪佛龙。
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公开(公告)号：EP2845580A4
公开(公告)日：2015-12-09
申请号：EP13781614
申请日：2013-04-26
Applicant: KAO CORP
Inventor： ASHIDA ARISA , HORI TAKAAKI , YAMAKI KAZUHIRO , NOMURA TOMOKO , SUGATA KEIICHI
Abstract: Provided is a bath agent composition capable of satisfactorily exhibiting blood circulation promoting effect by generating carbon dioxide gas by comprising a carbonate and an organic acid therein and capable of satisfactorily exhibiting an additional effect by imparting high preservation stability. The bath agent composition comprises the following components: (A) a carbonate comprising 30 mass% or more of a dialkali metal carbonate (A1); (B) an organic acid; and (C) a CGRP response promoter.
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公开(公告)号：JP2004337317A
公开(公告)日：2004-12-02
申请号：JP2003136541
申请日：2003-05-14
Inventor： SUGATA KEIICHI , NISHIJIMA TAKASHI , KITAHARA TAKASHI
Abstract: PROBLEM TO BE SOLVED: To evaluate a conspicuity of pores with high reproducibility.
SOLUTION: The conspicuity of the pores is evaluated by making measurement data on a shape of an interface between the epidermis-dermis of an epidermal structure around the pores serve as an evaluation parameter for evaluating the conspicuity of the pores. In terms of the evaluation parameter, a plurality of images different in measurement depth are acquired as to the pore and a region around them by using a confocal laser scanning microscope. In the images, an islandlike region, which is composed of the dermis, appears in an epidermal region around the pores as the measurement depth gets greater; the islandlike region gets larger as the measurement depth gets further greater; and the image, wherein the outside of the emidermal region including the islandlike region serves as a dermal region, is found out. In the image, an area (area S of a dermal papillae forming region) surrounded by the dermal region can be used.
COPYRIGHT: (C)2005,JPO&NCIPIAbstract translation: 要解决的问题：评估具有高再现性的孔的显着性。 解决方案：通过对孔周围的表皮结构的表皮真皮之间的界面的形状进行测量数据来评估孔的显着性，作为评估孔的明显性的评估参数。 在评价参数方面，通过使用共聚焦激光扫描显微镜，获得与孔相近的测量深度不同的多个图像和周围的区域。 在图像中，由真皮组成的岛状区域随着测量深度的增加而出现在毛孔周围的表皮区域中; 随着测量深度进一步增大，岛状区域变大; 并且发现其中包括岛状区域的表皮区域的外部用作皮肤区域的图像。 在图像中，可以使用由真皮区域包围的区域（真皮乳头形成区域的面积S）。 版权所有（C）2005，JPO＆NCIPI
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Patent Agency Ranking
公开(公告)号：JP2009051835A
公开(公告)日：2009-03-12
申请号：JP2008201166
申请日：2008-08-04
Inventor： NAGASHIMA YOSHINAO , SUGATA KEIICHI , YADA YUKIHIRO , FUKUDA KAZUYUKI
IPC: A61K31/045 , A23G3/34 , A23L1/30 , A61K8/02 , A61K8/34 , A61K9/00 , A61K31/05 , A61P25/02 , A61P25/20 , A61P25/22 , A61Q13/00 , A61Q19/00
CPC classification number: A61K31/045 , A61K9/007
Abstract: PROBLEM TO BE SOLVED: To provide an autonomic nerve regulating agent exhibiting sedative action and the like to a person in a condition of excessively sympathetic nerve ascendant and, conversely, exhibiting actions of returning physiologically most suitable conditions to a person in a condition of excessively parasympathetic nerve ascendant, regardless of individual variation in sensitivity to or preference for fragrance. SOLUTION: The autonomic nerve regulating agent, a sleep improver and a stress relaxing agent, each containing a sesquiterpene alcohol having ≥250°C boiling point individually and having odor practically lower than a threshold level. As the sesquiterpene alcohol, cedrol is preferable. The autonomic nerve regulating agent can be applied to sundries such as an indoor fragrance and a mask, and several kinds of fiber products including seat covers, bedclothes, wall paper, interior materials and clothes. COPYRIGHT: (C)2009,JPO&INPIT
Abstract translation: 要解决的问题：提供一种在过度交感神经上升的情况下向人展示镇静作用等的自主神经调节剂，相反地，表现出将生理上最适合的病症恢复到病情的人的作用 过度副交感神经上升，而不考虑对香味敏感度或偏爱度的个体变化。 解决方案：自主神经调节剂，睡眠改善剂和应激缓解剂，各自含有单独具有≥250℃沸点的倍半萜醇，具有低于阈值水平的气味。 作为倍半萜醇，优选雪松醇。 自主神经调节剂可以应用于诸如室内香料和面膜的杂物，以及包括座椅套，床上用品，墙纸，内部材料和衣服在内的几种纤维制品。 版权所有（C）2009，JPO＆INPIT
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公开(公告)号：JP2012113191A
公开(公告)日：2012-06-14
申请号：JP2010263221
申请日：2010-11-26
Inventor： SUGATA KEIICHI , OSANAI TSUKASA
Abstract: PROBLEM TO BE SOLVED: To provide a method to form an image of a skin structure with which a vascular network can be observed in a high resolution image of the skin structure and also changes in blood flow volume in the vascular network can be observed.SOLUTION: The method captures a laser microscopic moving image of skin, forms plural luminance difference images between frames of the moving image, adds up the luminance difference images, and thereby forms an image of blood flow. The method further combines the image of the blood flow and a confocal laser reflection microscopic image of the same region as the image of the blood flow, and thereby shows the image of the blood flow in the skin structure.
Abstract translation: 要解决的问题：提供一种在皮肤结构的高分辨率图像中形成可以观察到血管网络的皮肤结构的图像的方法，并且还可以在血管网络中的血流量的变化 观察到的。 解决方案：该方法捕获皮肤的激光微观运动图像，在运动图像的帧之间形成多个亮度差分图像，将亮度差分图像相加，从而形成血流图像。 该方法进一步结合血流图像和与血流图像相同区域的共聚焦激光反射显微镜图像，从而显示皮肤结构中血流的图像。 版权所有（C）2012，JPO＆INPIT
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公开(公告)号：JP2004339120A
公开(公告)日：2004-12-02
申请号：JP2003136542
申请日：2003-05-14
Inventor： SUGATA KEIICHI , NISHIJIMA TAKASHI
IPC: A61K8/67 , A61K8/00 , A61K31/593 , A61P17/00 , A61K7/00
Abstract: PROBLEM TO BE SOLVED: To provide a new agent for ameliorating pore conspicuousness.
SOLUTION: The pore conspicuousness-ameliorating agent or pore-contractive agent comprises an activated vitamin D3 or a derivative thereof as active ingredient.
COPYRIGHT: (C)2005,JPO&NCIPI-
公开(公告)号：JP2009142597A
公开(公告)日：2009-07-02
申请号：JP2007325726
申请日：2007-12-18
Inventor： SUGATA KEIICHI , SAKAI SHINGO
Abstract: PROBLEM TO BE SOLVED: To precisely and highly reliably determine melanin in a viable tissue without injuring the viable tissue.
SOLUTION: A melanin distribution visualizing method is the method for visualizing a melanin distribution by allowing the attenuation curve of auto-fluorescence in melanin existing in the viable tissue to approach a secondary attenuation curve through the use of a device, which planarly irradiates the prescribed depth of the viable tissue with a laser beam by planar scanning, and receives the auto-fluorescence from the tissue, and then, determining coefficients
τ1 and
τ2 concerning a fluorescent life and coefficients A
1 and A
2 concerning amplitude with respect to the fluorescent life. The method is characterized by setting 12-33 thresholds in A
1 /A
2 , and determining the fluorescence exceeding the thresholds to be the fluorescence caused by melanin.
COPYRIGHT: (C)2009,JPO&INPITAbstract translation: 要解决的问题：精确和高度可靠地确定活组织中的黑色素而不损伤活组织。 解决方案：黑色素分布可视化方法是通过使存在于活组织中的黑色素中的自身荧光的衰减曲线通过使用平面照射的装置接近二次衰减曲线来显现黑色素分布的方法 通过平面扫描具有激光束的活组织的规定深度，并从组织接收自体荧光，然后确定与荧光体相关的系数
τ1和 τ2 寿命和相对于荧光寿命的振幅的系数A SB <1>和A 2 。 该方法的特征在于在A 1 2 中设定12-33个阈值，并将超过阈值的荧光测定为由黑色素引起的荧光。 版权所有（C）2009，JPO＆INPIT -
公开(公告)号：JP2001112742A
公开(公告)日：2001-04-24
申请号：JP30026499
申请日：1999-10-21
Applicant: KAO CORP
Inventor： NAGASHIMA YOSHINAO , SUGATA KEIICHI , YADA YUKIHIRO
Abstract: PROBLEM TO BE SOLVED: To allow even an ordinary person to noninvasively and easily evaluate the condition of her skin, such as the degree of fatigue, etc. SOLUTION: Laser beams are made to simultaneously impinge on a plurality of measuring points on the skin, and the laser beams reflected from the skin are received and converted into blood flow signals. Signals corresponding to two or more specific frequency bandwidths are extracted from the blood flow signals, and the signal strengths which correspond to the different frequency bandwidths are compared with each other to evaluate the condition of the skin.
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