Abstract:
The amide derivative of the present invention is one represented by general formula (I) or (II). The dermatologic preparation of the present invention is one containing said amide derivative. In formula (I), R1 represents a straight-chain or branched, saturated or unsaturated hydrocarbon group carrying 10 to 40 carbon atoms; R2 represents a straight-chain or branched, saturated or unsaturated hydrocarbon group carrying 3 to 39 carbon atoms; R3 represents a group containing at least one group represented by formula (A), wherein R?4 and R5¿ each represents a hydrogen atom or a straight-chain or branched or cyclic, saturated or unsaturated hydrocarbon group, or R?4 and R5¿ may form a hydrocarbon group together; and X represents (B). In formula (II), R11 represents a straight-chain or branched hydrocarbon group carrying 10 to 40 carbon atoms; R12 represents a straight-chain or branched hydrocarcon group carrying 1 to 39 carbon atoms; R13 represents a hydrogen atom or a hydrocarbon group carrying 1 to 6 carbon atoms; and R14 represents a hydrogen atom or a hydrocarbon group having a straight-chain, branched or cyclic structure and carrying 1 to 40 carbon atoms which may contain an oxygen atom.
Abstract:
An amine derivative of following general formula (I) or (II) (wherein R represents a heteroatom-containing C1-C40 hydrocarbon group which may have a ring structure, etc.; R to R each represent a C1-C10 hydrocarbon group, hydrogen, etc.; A represents (i) or R -Z-R (CH2)n-; B represents hydrogen, a C1-C10 hydrocarbon group, nitrogen, etc.; and C represents hydrogen, a C1-C10 hydrocarbon group, nitrogen, alcohol residue, phosphoric acid residue, etc.); a dermatologic preparation containing the same; and a process for producing the amine derivative. The amine derivative has excellent effects of smoothing wrinkles and improving keratodermia.
Abstract:
PCT No. PCT/JP92/01210 Sec. 371 Date Mar. 23, 1994 Sec. 102(e) Date Mar. 23, 1994 PCT Filed Sep. 22, 1992 PCT Pub. No. WO93/05763 PCT Pub. Date Apr. 1, 1993A composition for external skin care comprising an amine derivative represented by the following formula (1), (1) wherein R1 is a linear, branched, or cyclic saturated or unsaturated hydrocarbon group having 4-40 carbon atoms, and R2, R3, R4, R5 and R6 are individually a hydrogen atom or a hydrocarbon group having 1-10 carbon atoms, which may be substituted or unsubstituted by 1 or more hydroxy groups; or an acid addition salt thereof, in an amount from 0.0001 to less than 0.1% by weight; and a method of curing wrinkles and keratinization of the skin characterized by applying said amine derivative or its salt to the skin.
Abstract:
The autonomic nerve regulating agent of the present invention, which has a sedative action, sleep inducing action, and stress mitigating action in individuals, regardless of individual variation in sensitivity to or preference for fragrance, contains as an active ingredient a sesquiterpene alcohol with a boiling point of 250 DEG C or higher, particularly cedrol.
Abstract:
PCT No. PCT/JP92/01210 Sec. 371 Date Mar. 23, 1994 Sec. 102(e) Date Mar. 23, 1994 PCT Filed Sep. 22, 1992 PCT Pub. No. WO93/05763 PCT Pub. Date Apr. 1, 1993A composition for external skin care comprising an amine derivative represented by the following formula (1), (1) wherein R1 is a linear, branched, or cyclic saturated or unsaturated hydrocarbon group having 4-40 carbon atoms, and R2, R3, R4, R5 and R6 are individually a hydrogen atom or a hydrocarbon group having 1-10 carbon atoms, which may be substituted or unsubstituted by 1 or more hydroxy groups; or an acid addition salt thereof, in an amount from 0.0001 to less than 0.1% by weight; and a method of curing wrinkles and keratinization of the skin characterized by applying said amine derivative or its salt to the skin.
Abstract:
The autonomic nerve regulating agent of the present invention, which has a sedative action, sleep inducing action, and stress mitigating action in individuals, regardless of individual variation in sensitivity to or preference for fragrance, contains as an active ingredient a sesquiterpene alcohol with a boiling point of 250 DEG C or higher, particularly cedrol.
Abstract:
A beauty treatment process comprises massage in the direction of the skin fibers. The massage consists of a combination of massage in the arterial and vein blood flow directions.
Abstract:
The autonomic nerve regulating agent of the present invention, which has a sedative action, sleep inducing action, and stress mitigating action in individuals, regardless of individual variation in sensitivity to or preference for fragrance, contains as an active ingredient a sesquiterpene alcohol with a boiling point of 250 DEG C or higher, particularly cedrol.
Abstract:
Methods for easily achieving valuable cosmetic effects through massage even by ordinary people which comprise massaging the skin along the arterial blood flow and then along the venous blood flow, or applying onto the skin surface a cosmetic containing disintegrable particles followed by massage, when the pulse, skin vessels, skin temperature or skin blood flows are not at rest but in a n accelerated state. Further, the methods comprise, in the process of washing the skin with a cleanser or a detergent followed by the application of a skin-care cosmetic, massaging the skin with the use of a massaging cosmetic containing disintegrable particles after washing with the cleanser or the detergent and before the application of the skin-care cosmetic. These methods contribute to the performance of effective skin care.