公开(公告)号：EP3536790A1

公开(公告)日：2019-09-11

申请号：EP17866684.8

申请日：2017-11-03

Applicant: Korea Institute of Science and Technology

Inventor： PAN, Cheol-Ho ,  SHIN, Bok-Kyu ,  ERDENE-OCHIR, Erdenedolgor ,  KIM, Sang Min

IPC: C12N15/79 ,  C12P21/00 ,  C07K14/485 ,  A61K8/64 ,  A61Q19/00 ,  A61Q19/08

Abstract: The present specification relates to: a vector comprising a promoter of SEQ ID NO: 1 and a human epidermal growth factor (hEGF) exon, which includes a gene coding for hEGF; microalgae transformed with the vector; a method for producing a hEGF protein and/or a PTD-hEGF protein by using the transformed microalgae; and a cosmetic composition containing the hEGF and/or PTD-hEGF protein(s) produced according to the production method. The hEGF and PTD-hEGF proteins, produced according to an aspect of the present invention, can fundamentally block the risk of endotoxicity, unlike a hEGF protein produced from conventional E. coli, thereby being usable as a raw material for eco-friendly cosmetic products.