公开(公告)号：AU2019299339A1

公开(公告)日：2021-01-21

申请号：AU2019299339

申请日：2019-07-01

Applicant: LEIDOS INC

Inventor： CHAPPELL STEPHEN A ,  MAURO VINCENT P ,  DRESIOS JOHN

IPC: C12P21/00 ,  C07H21/04 ,  C12N15/00 ,  C12P21/04 ,  C12P21/06 ,  C12Q1/68

Abstract: The present disclosure provides materials and methods for cell-free expression of epitopes for immunotherapy applications. In particular, the present disclosure provides materials and methods for expressing concatenated epitopes using a cell-free protein synthesis platform for high throughput, large scale, and unbiased epitope screening and the generation of multi-epitope vaccines.

公开(公告)号：CA3104859A1

公开(公告)日：2020-01-09

申请号：CA3104859

申请日：2019-07-01

Applicant: LEIDOS INC

Inventor： CHAPPELL STEPHEN A ,  MAURO VINCENT P ,  DRESIOS JOHN

IPC: C12P21/00 ,  C07H21/04 ,  C12N15/00 ,  C12P21/04 ,  C12P21/06 ,  C12Q1/68

Abstract: The present disclosure provides materials and methods for cell-free expression of epitopes for immunotherapy applications. In particular, the present disclosure provides materials and methods for expressing concatenated epitopes using a cell-free protein synthesis platform for high throughput, large scale, and unbiased epitope screening and the generation of multi-epitope vaccines.