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    AMELOGENIN SNP ON CHROMOSOME X
    2.
    发明申请
    AMELOGENIN SNP ON CHROMOSOME X 审中-公开
    AMELOGENIN SNP染色体X

    公开(公告)号：WO2011020075A3

    公开(公告)日：2011-04-14

    申请号：PCT/US2010045544

    申请日：2010-08-13

    Applicant: LIFE TECHNOLOGIES CORP

    Inventor： MULERO JULIO ,  GREEN ROBERT ,  LAGACE ROBERT ,  HENNESSY LORI

    IPC: C12Q1/68 ,  C12P19/34 ,  G01N33/48

    CPC classification number: C07H21/04 ,  C12Q1/6879 ,  C12Q2600/156

    Abstract: Disclosed are methods for gender determination in the intron 1 region of the amelogenin locus and a newly discovered single nucleotide polymorphism (SNP) within the X chromosome of the amelogenin locus which can cause allelic dropout. Also disclosed are kits useful in gender determination.

    Abstract translation: 公开了用于在釉原蛋白基因座的内含子1区域中确定性别的方法以及可能导致等位基因辍学的釉原蛋白基因座的X染色体内新发现的单核苷酸多态性（SNP）的方法。 还公开了用于性别决定的试剂盒。

    X-STR MULTIPLEX SYSTEM
    4.
    发明公开
    X-STR MULTIPLEX SYSTEM 审中-公开
    X-STR-MULTIPLEXSYSTEM

    公开(公告)号：EP2561101A4

    公开(公告)日：2013-12-25

    申请号：EP11772824

    申请日：2011-04-22

    Applicant: LIFE TECHNOLOGIES CORP

    Inventor： CHANG CHIEN-WEI ,  HENNESSY LORI

    IPC: C12Q1/68 ,  C12N15/11

    CPC classification number: C12Q1/6876 ,  C12Q1/6888 ,  C12Q2600/16

    Abstract: The methods and compositions provided herein relate to the discovery of several new STR alleles and a 20-plex multiplex assay for markers found on the human X chromosome. These X-STR markers have been found when used in a multiplex reaction to provide higher discriminatory power when compared to existing X-STR assay kits available commercially. Embodiments of the present teachings include methods for allelic determination of X-STR markers, amplification primers for the analysis of X-STR markers in a multiplex reaction, allelic ladders for analysis of X-STR markers, and kits for the analysis of X-STR markers.

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